Current state-of-the-art two-stage detectors heavily rely on region proposals to guide the accurate detection for objects. In previous region proposal approaches, the interaction between different functional modules is correlated weakly, which limits or decreases the performance of region proposal approaches. In this paper, we propose a novel two-stage strong correlation learning framework, abbreviated as SC-RPN, which aims to set up stronger relationship among different modules in the region proposal task. Firstly, we propose a Light-weight IoU-Mask branch to predict intersection-over-union (IoU) mask and refine region classification scores as well, it is used to prevent high-quality region proposals from being filtered. Furthermore, a sampling strategy named Size-Aware Dynamic Sampling (SADS) is proposed to ensure sampling consistency between different stages. In addition, point-based representation is exploited to generate region proposals with stronger fitting ability. Without bells and whistles, SC-RPN achieves AR100014.5% higher than that of Region Proposal Network (RPN), surpassing all the existing region proposal approaches. We also integrate SC-RPN into Fast R-CNN and Faster R-CNN to test its effectiveness on object detection task, the experimental results achieve a gain of 3.2% and 3.8% in terms of mAP compared to the original ones.