Demo Data from VLDB 2026 / reviewers in the wild / expert
Bowen Tan
dblp:193/7851
· DBLP profile ↗
17ranked-venue papers
10as first author
10since 2021 · last 2025
—ORCID · conflict
Domains — the database's venue-derived domains; a paper can count in several
Artificial intelligence and machine learning · 10 · 4 first-author · 5 since 2021Computer networks · 3 · 3 first-author · 3 since 2021Graphics, computer vision, multimedia, augmented reality and games · 3 · 1 first-author · 1 since 2021Systems, architecture and hardware · 1 · 1 first-author · 1 since 2021Applied, interdisciplinary, general and emerging computing · 1 · 1 first-author
Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.
| Artificial intelligence
8 papers |
Efficient and distributed learning · 25% Language models and text generation · 24% Question answering and dialogue systems · 16% | |
| Network and information security
1 paper |
Privacy and data protection · 100% | |
| Databases, data mining, and information retrieval
1 paper |
Data models and query languages · 100% |
Topics — the 20 heaviest of 23, each with the papers that count most for it
| Topic | Weight | Papers | Last | Evidence papers |
|---|---|---|---|---|
Machine learning › Efficient and distributed learning
model compression |
0.9 | 2 | 2025 | Cappy: Outperforming and Boosting Large Multi-Task LMs with a Small Scorer · NeurIPS 2023 Synthesizing Privacy-Preserving Text Data via Finetuning *without* Finetuning Billion-Scale LLMs · ICML 2025 |
Privacy and data protection
differential privacy |
0.9 | 1 | 2025 | Synthesizing Privacy-Preserving Text Data via Finetuning *without* Finetuning Billion-Scale LLMs · ICML 2025 |
Privacy and data protection
synthetic text generation |
0.9 | 1 | 2025 | Synthesizing Privacy-Preserving Text Data via Finetuning *without* Finetuning Billion-Scale LLMs · ICML 2025 |
Machine learning › Efficient and distributed learning › large-scale learning
model scaling |
0.8 | 1 | 2024 | Model-GLUE: Democratized LLM Scaling for A Large Model Zoo in the Wild · NeurIPS 2024 |
Machine learning › Learning paradigms › multi-task learning
multi-task language model |
0.7 | 1 | 2023 | Cappy: Outperforming and Boosting Large Multi-Task LMs with a Small Scorer · NeurIPS 2023 |
Natural language and speech › Language models and text generation
text generation evaluation |
0.5 | 1 | 2021 | Compression, Transduction, and Creation: A Unified Framework for Evaluating Natural Language Generation · EMNLP (1) 2021 |
Natural language and speech › Language models and text generation › text summarization › opinion summarization
aspect-based summarization |
0.4 | 1 | 2020 | Summarizing Text on Any Aspects: A Knowledge-Informed Weakly-Supervised Approach · EMNLP (1) 2020 |
Natural language and speech › Question answering and dialogue systems › task-oriented dialogue
dialogue state tracking |
0.4 | 1 | 2020 | Schema-Guided Multi-Domain Dialogue State Tracking with Graph Attention Neural Networks · AAAI 2020 |
Natural language and speech › Question answering and dialogue systems › task-oriented dialogue › dialogue state tracking
multi-domain dialogue state tracking |
0.4 | 1 | 2020 | Schema-Guided Multi-Domain Dialogue State Tracking with Graph Attention Neural Networks · AAAI 2020 |
Natural language and speech › Language models and text generation
text summarization |
0.4 | 1 | 2020 | Summarizing Text on Any Aspects: A Knowledge-Informed Weakly-Supervised Approach · EMNLP (1) 2020 |
Data models and query languages
schema graph |
0.4 | 1 | 2020 | Schema-Guided Multi-Domain Dialogue State Tracking with Graph Attention Neural Networks · AAAI 2020 |
Natural language and speech › Question answering and dialogue systems
dialogue management |
0.4 | 1 | 2019 | AgentGraph: Toward Universal Dialogue Management With Structured Deep Reinforcement Learning · IEEE ACM Trans. Audio Speech Lang. Process. 2019 |
Machine learning › Reinforcement learning
multi-agent reinforcement learning |
0.4 | 1 | 2019 | AgentGraph: Toward Universal Dialogue Management With Structured Deep Reinforcement Learning · IEEE ACM Trans. Audio Speech Lang. Process. 2019 |
Machine learning › Reinforcement learning
reward learning |
0.4 | 1 | 2019 | Learning Data Manipulation for Augmentation and Weighting · NeurIPS 2019 |
Natural language and speech › Language models and text generation
large language model |
0.3 | 1 | 2025 | Synthesizing Privacy-Preserving Text Data via Finetuning *without* Finetuning Billion-Scale LLMs · ICML 2025 |
Natural language and speech › Language models and text generation › trustworthy language model › privacy-preserving inference
privacy-preserving text generation |
0.3 | 1 | 2025 | Synthesizing Privacy-Preserving Text Data via Finetuning *without* Finetuning Billion-Scale LLMs · ICML 2025 |
Machine learning › Efficient and distributed learning
model reuse |
0.2 | 1 | 2024 | Model-GLUE: Democratized LLM Scaling for A Large Model Zoo in the Wild · NeurIPS 2024 |
Knowledge, reasoning and agents › Knowledge representation and reasoning › knowledge graph
conceptnet |
0.1 | 1 | 2020 | Summarizing Text on Any Aspects: A Knowledge-Informed Weakly-Supervised Approach · EMNLP (1) 2020 |
Knowledge, reasoning and agents › Knowledge representation and reasoning
knowledge graph |
0.1 | 1 | 2020 | Summarizing Text on Any Aspects: A Knowledge-Informed Weakly-Supervised Approach · EMNLP (1) 2020 |
Machine learning › Reinforcement learning › transfer learning in reinforcement learning
policy transfer |
0.1 | 1 | 2019 | AgentGraph: Toward Universal Dialogue Management With Structured Deep Reinforcement Learning · IEEE ACM Trans. Audio Speech Lang. Process. 2019 |
Methods — techniques the papers use, named apart from their topics
differential privacy · 1.7conditional generator · 1.7clustering-based topic model · 1.7DP histogram · 1.7recurrent graph attention network · 0.9graph attention network · 0.9prompt tuning · 0.7instruction tuning · 0.7in-context learning · 0.7alignment prediction · 0.5
| Year | Publication | Venue | Position |
|---|---|---|---|
| 2025 | The Low-Latency UCIe-Compliant Spiral Layouts of TSV Arrays Against the Clustered FaultsabstractThe chiplet based integrated system contains lots of inter-die interconnections. The through silicon vias (TSVs) and micro bumps are the common components of the vertical electrical interconnections in the $2.5 \mathrm{D} / 3 \mathrm{D}$ multi-die integration circuits. They are usually laid out as arrays to regulate the routing rules. Faults may occur in the TSVs, and the redundant resources based self-repair mechanisms are introduced to improve the yield of the entire integrated chip. In the Universal Chiplet Interconnect Express (UCIe) standard, each advanced package module contains 32 data lanes and 2 redundant lanes, and the shift chain based intra-module self-repair mechanism is defined. However, the faults are usually clustered in certain region of the TSV array. The intra-module self-repair mechanism of UCIe standard is not able to cope with the cases that more than 2 clustered faults occur simultaneously in one module. An effective idea to improve the repair rate is to distribute the faults into different modules by regrouping the layout of TSV array. This work reports some new spiral layouts of rectangular and hexagonal TSV arrays. The self-repair schemes based on the proposed layouts are UCIe-compliant. Simulation results present that the proposed self-repair schemes are able to repair the clustered faults in TSV array with the low repair latencies. Bowen Tan, Xiaole Cui, Zhaohong Lin |
ATS | 1 |
| 2025 | Synthesizing Privacy-Preserving Text Data via Finetuning *without* Finetuning Billion-Scale LLMsabstractSynthetic data offers a promising path to train models while preserving data privacy. Differentially private (DP) finetuning of large language models (LLMs) as data generator is effective, but is impractical when computation resources are limited. Meanwhile, prompt-based methods such as private evolution depend heavily on the manual prompts, and ineffectively use private information in their iterative data selection process. To overcome these limitations, we propose CTCL (Data Synthesis with ConTrollability and CLustering), a novel framework for generating privacy-preserving synthetic data without extensive prompt engineering or billion-scale LLM finetuning. CTCL pretrains a lightweight 140M conditional generator and a clustering-based topic model on large-scale public data. To further adapt to the private domain, the generator is DP finetuned on private data for fine-grained textual information, while the topic model extracts a DP histogram representing distributional information. The DP generator then samples according to the DP histogram to synthesize a desired number of data examples. Evaluation across five diverse domains demonstrates the effectiveness of our framework, particularly in the strong privacy regime. Systematic ablation validates the design of each framework component and highlights the scalability of our approach. Bowen Tan, Eric P. Xing, Zhiting Hu |
ICML | 1 |
| 2025 | Throughput-Optimal Multi-Link Access for Wi-Fi 7 via Multi-Agent Reinforcement LearningabstractMulti-link operation (MLO) is one of the pivotal new features in the upcoming IEEE 802.11be Wi-Fi 7 networks. To break the performance limit of traditional random-access-based Wi-Fi, we propose a novel distributed multi-link access scheme for Wi-Fi 7, leveraging the Multi-Agent Deep Deterministic Policy Gradient (MADDPG) algorithm. Specifically, a novel parameter, denoted as access opportunity, is introduced as the state transition time step in the decentralized partially observable Markov decision process, which enables the unified modeling of multiple links with varying transmission rates. With the proposed scheme, agents trained in a specific single-link network environment can be directly deployed in multi-link scenarios with varying link transmission parameters, significantly reducing training complexity. The proposed scheme undergoes evaluation in diverse network scenarios, which outperforms the throughput limit of standard multi-link Wi-Fi networks by up to 23.9%, ensures fairness among devices and is robust to environment dynamics. Bowen Tan, Yayu Gao, Xinghua Sun |
WCNC | 1 |
| 2025 | Fast MLE and MAPE-Based Device Activity Detection for Grant-Free Access via PSCA and PSCA-NetabstractFast and accurate device activity detection is the critical challenge in grant-free access for supporting massive machine-type communications (mMTC) and ultra-reliable low-latency communications (URLLC) in 5G and beyond. The state-of-the-art methods have unsatisfactory error rates or computation times. To address these outstanding issues, we propose new maximum likelihood estimation (MLE) and maximum a posterior estimation (MAPE) based device activity detection methods for known and unknown pathloss that achieve superior error rate and computation time tradeoffs using optimization and deep learning techniques. Specifically, we investigate four non-convex optimization problems for MLE and MAPE in the two pathloss cases, with one MAPE problem being formulated for the first time. For each non-convex problem, we develop an innovative parallel iterative algorithm using the parallel successive convex approximation (PSCA) method. Each PSCA-based algorithm allows parallel computations, uses up to the objective function’s second-order information, converges to the problem’s stationary points, and has a low per-iteration computational complexity compared to the state-of-the-art algorithms. Then, for each PSCA-based iterative algorithm, we present a deep unrolling neural network implementation, called PSCA-Net, to further reduce the computation time. Each PSCA-Net elegantly marries the underlying PSCA-based algorithm’s parallel computation mechanism with the parallelizable neural network architecture and effectively optimizes its step sizes based on vast data samples to speed up the convergence. Numerical results demonstrate that the proposed methods can significantly reduce the error rate and computation time compared to the state-of-the-art methods, revealing their significant values for grant-free access. Bowen Tan, Ying Cui 0001 |
IEEE Trans. Wirel. Commun. | 1 |
| 2024 | Fast MLE-Based Device Activity Detection for Massive Grant-Free Access via PSCA and PSCANetabstractFast and accurate device activity detection is the critical challenge in grant-free access for supporting massive machine-type communications (mMTC). The state-of-the-art methods have an unsatisfactory error rate or computation time. To address these outstanding issues, we propose new maximum likelihood estimation (MLE)-based device activity detection methods that achieve superior tradeoffs between the error rate and computation time using optimization and deep learning techniques. Specifically, we propose an innovative parallel successive convex approximation (PSCA) algorithm for solving the noncon-vex MLE problem. We show that it allows parallel computations, uses up to the objective function’s second-order information, converges to the problem’s stationary points, and has a low per-iteration computational complexity compared to the state-of-the-art algorithms for the MLE problem. Then, we propose a PSCA-driven deep unrolling neural network implementation, called PSCANet, to reduce the overall computation time of PSCA. PSCANet elegantly marries PSCA’s parallel computation mechanism with the parallelizable neural network architecture and effectively optimizes its step sizes based on vast data samples. Numerical results demonstrate that PSCA and PSCANet can significantly reduce the error rate and computation time compared to the state-of-the-art methods, revealing their significant values for mMTC in 5G and beyond. Bowen Tan, Ying Cui 0001 |
GLOBECOM | 1 |
| 2024 | Model-GLUE: Democratized LLM Scaling for A Large Model Zoo in the Wild
Guoheng Sun, Ruisi Cai, Pingzhi Li, Peihao Wang, Bowen Tan, Yexiao He, Beidi Chen, Binhang Yuan, Hongyi Wang 0001, Ang Li 0005, Zhangyang Wang, Tianlong Chen 0001 |
NeurIPS | 7 |
| 2023 | MFAT: A Multi-Level Feature Aggregated Transformer for Person Re-IdentificationabstractRecently, with the development of the Transformer, re-identification (ReID) has great success in various applications. Existing works prefer to utilize the Transformer’s highest-level information as its discriminative feature, which focuses on a few concentrated parts or areas. However, in ReID filed, under such various scenes and camera views, only using a few concentrated parts to distinguish the query person is insufficient. Meanwhile, we find that Transformer’s lower-level information is also helpful for the recognition accuracy of the query person, especially, when the scene changes greatly. Therefore, we propose a Multi-level Feature Aggregated Transformer for person re-identification (MFAT) with high performance. To aggregate multi-level information, two novel modules are carefully designed. (i) The Global Content and Structure Aggregation (GCSA) module is proposed to aggregate multi-level information in a global manner. (ii) The Local Convolution Aggregation (LCA) module which consists of a series of convolutional blocks, is introduced to aggregate multi-level features with local operations. To the best of our knowledge, this is the first work to aggregate multi-level features with a Transformer backbone for person ReID task. Experiment results show that our method has achieved state-of-the-art on three person ReID benchmarks, with both Pyramid Vision Transformer (PVT) and Vision Transformer (ViT) backbones. Bowen Tan, Linfeng Xu 0001, Zihuan Qiu, Qingbo Wu 0001, Fanman Meng |
ICASSP | 1 |
| 2023 | Cappy: Outperforming and Boosting Large Multi-Task LMs with a Small ScorerabstractLarge language models (LLMs) such as T0, FLAN, and OPT-IML excel in multi-tasking under a unified instruction-following paradigm, where they also exhibit remarkable generalization abilities to unseen tasks. Despite their impressive performance, these LLMs, with sizes ranging from several billion to hundreds of billions of parameters, demand substantial computational resources, making their training and inference expensive and inefficient. Furthermore, adapting these models to downstream applications, particularly complex tasks, is often unfeasible due to the extensive hardware requirements for finetuning, even when utilizing parameter-efficient approaches such as prompt tuning. Additionally, the most powerful multi-task LLMs, such as OPT-IML-175B and FLAN-PaLM-540B, are not publicly accessible, severely limiting their customization potential. To address these challenges, we introduce a pretrained small scorer, \textit{Cappy}, designed to enhance the performance and efficiency of multi-task LLMs. With merely 360 million parameters, Cappy functions either independently on classification tasks or serve as an auxiliary component for LLMs, boosting their performance. Moreover, Cappy enables efficiently integrating downstream supervision without requiring LLM finetuning nor the access to their parameters. Our experiments demonstrate that, when working independently on 11 language understanding tasks from PromptSource, Cappy outperforms LLMs that are several orders of magnitude larger. Besides, on 45 complex tasks from BIG-Bench, Cappy boosts the performance of the advanced multi-task LLM, FLAN-T5, by a large margin. Furthermore, Cappy is flexible to cooperate with other LLM adaptations, including finetuning and in-context learning, offering additional performance enhancement. Bowen Tan, Eric P. Xing, Zhiting Hu, Jindong Chen |
NeurIPS | 1 |
| 2021 | Compression, Transduction, and Creation: A Unified Framework for Evaluating Natural Language GenerationabstractNatural language generation (NLG) spans a broad range of tasks, each of which serves for specific objectives and desires different properties of generated text.The complexity makes automatic evaluation of NLG particularly challenging.Previous work has typically focused on a single task and developed individual evaluation metrics based on specific intuitions.In this paper, we propose a unifying perspective based on the nature of information change in NLG tasks, including compression (e.g., summarization), transduction (e.g., text rewriting), and creation (e.g., dialog).Information alignment between input, context, and output text plays a common central role in characterizing the generation.With automatic alignment prediction models, we develop a family of interpretable metrics that are suitable for evaluating key aspects of different NLG tasks, often without need of gold reference data.Experiments show the uniformly designed metrics achieve stronger or comparable correlations with human judgement compared to state-of-the-art metrics in each of diverse tasks, including text summarization, style transfer, and knowledgegrounded dialog. 1 Mingkai Deng, Bowen Tan, Zhengzhong Liu 0001, Eric P. Xing, Zhiting Hu |
EMNLP (1) | 2 |
| 2021 | Progressive Generation of Long Text with Pretrained Language ModelsabstractBowen Tan, Zichao Yang, Maruan Al-Shedivat, Eric Xing, Zhiting Hu. Proceedings of the 2021 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies. 2021. Bowen Tan, Maruan Al-Shedivat, Eric P. Xing, Zhiting Hu |
NAACL-HLT | 1 |
| 2020 | Schema-Guided Multi-Domain Dialogue State Tracking with Graph Attention Neural NetworksabstractDialogue state tracking (DST) aims at estimating the current dialogue state given all the preceding conversation. For multi-domain DST, the data sparsity problem is also a major obstacle due to the increased number of state candidates. Existing approaches generally predict the value for each slot independently and do not consider slot relations, which may aggravate the data sparsity problem. In this paper, we propose a Schema-guided multi-domain dialogue State Tracker with graph attention networks (SST) that predicts dialogue states from dialogue utterances and schema graphs which contain slot relations in edges. We also introduce a graph attention matching network to fuse information from utterances and graphs, and a recurrent graph attention network to control state updating. Experiment results show that our approach obtains new state-of-the-art performance on both MultiWOZ 2.0 and MultiWOZ 2.1 benchmarks. Lu Chen 0002, Boer Lv, Su Zhu, Bowen Tan, Kai Yu 0004 |
AAAI | 5 |
| 2020 | Summarizing Text on Any Aspects: A Knowledge-Informed Weakly-Supervised ApproachabstractGiven a document and a target aspect (e.g., a topic of interest), aspect-based abstractive summarization attempts to generate a summary with respect to the aspect.Previous studies usually assume a small pre-defined set of aspects and fall short of summarizing on other diverse topics.In this work, we study summarizing on arbitrary aspects relevant to the document, which significantly expands the application of the task in practice.Due to the lack of supervision data, we develop a new weak supervision construction method and an aspect modeling scheme, both of which integrate rich external knowledge sources such as Concept-Net and Wikipedia.Experiments show our approach achieves performance boosts on summarizing both real and synthetic documents given pre-defined or arbitrary aspects. 1 Bowen Tan, Lianhui Qin, Eric P. Xing, Zhiting Hu |
EMNLP (1) | 1 |
| 2019 | Learning Data Manipulation for Augmentation and WeightingabstractManipulating data, such as weighting data examples or augmenting with new instances, has been increasingly used to improve model training. Previous work has studied various rule- or learning-based approaches designed for specific types of data manipulation. In this work, we propose a new method that supports learning different manipulation schemes with the same gradient-based algorithm. Our approach builds upon a recent connection of supervised learning and reinforcement learning (RL), and adapts an off-the-shelf reward learning algorithm from RL for joint data manipulation learning and model training. Different parameterization of the ``data reward'' function instantiates different manipulation schemes. We showcase data augmentation that learns a text transformation network, and data weighting that dynamically adapts the data sample importance. Experiments show the resulting algorithms significantly improve the image and text classification performance in low data regime and class-imbalance problems. Zhiting Hu, Bowen Tan, Ruslan Salakhutdinov, Tom M. Mitchell, Eric P. Xing |
NeurIPS | 2 |
| 2019 | AgentGraph: Toward Universal Dialogue Management With Structured Deep Reinforcement LearningabstractDialogue policy plays an important role in task-oriented spoken dialogue systems. It determines how to respond to users. The recently proposed deep reinforcement learning (DRL) approaches have been used for policy optimization. However, these deep models are still challenging for two reasons: first, many DRL-based policies are not sample efficient; and second, most models do not have the capability of policy transfer between different domains. In this paper, we propose a universal framework, AgentGraph, to tackle these two problems. The proposed AgentGraph is the combination of graph neural network (GNN) based architecture and DRL-based algorithm. It can be regarded as one of the multi-agent reinforcement learning approaches. Each agent corresponds to a node in a graph, which is defined according to the dialogue domain ontology. When making a decision, each agent can communicate with its neighbors on the graph. Under AgentGraph framework, we further propose dual GNN-based dialogue policy, which implicitly decomposes the decision in each turn into a high-level global decision and a low-level local decision. Experiments show that AgentGraph models significantly outperform traditional reinforcement learning approaches on most of the 18 tasks of the PyDial benchmark. Moreover, when transferred from the source task to a target task, these models not only have acceptable initial performance but also converge much faster on the target task. Lu Chen 0002, Zhi Chen 0006, Bowen Tan, Sishan Long, Milica Gasic, Kai Yu 0004 |
IEEE ACM Trans. Audio Speech Lang. Process. | 3 |
| 2018 | Structured Dialogue Policy with Graph Neural NetworksabstractRecently, deep reinforcement learning (DRL) has been used for dialogue policy optimization. However, many DRL-based policies are not sample-efficient. Most recent advances focus on improving DRL optimization algorithms to address this issue. Here, we take an alternative route of designing neural network structure that is better suited for DRL-based dialogue management. The proposed structured deep reinforcement learning is based on graph neural networks (GNN), which consists of some sub-networks, each one for a node on a directed graph. The graph is defined according to the domain ontology and each node can be considered as a sub-agent. During decision making, these sub-agents have internal message exchange between neighbors on the graph. We also propose an approach to jointly optimize the graph structure as well as the parameters of GNN. Experiments show that structured DRL significantly outperforms previous state-of-the-art approaches in almost all of the 18 tasks of the PyDial benchmark. Lu Chen 0002, Bowen Tan, Sishan Long, Kai Yu 0004 |
COLING | 2 |
| 2018 | Policy Adaptation for Deep Reinforcement Learning-Based Dialogue ManagementabstractPolicy optimization is the core part of statistical dialogue management. Deep reinforcement learning has been successfully used for dialogue policy optimization for a static pre-defined domain. However, when the domain changes dynamically, e.g. a new previously unseen concept (or slot) which can be then used as a database search constraint is added, or the policy for one domain is transferred to another domain, the dialogue state space and action sets both will change. Therefore, the model structures for different domains have to be different. This makes dialogue policy adaptation/transfer challenging. Here a multi -agent dialogue policy (MADP) is proposed to tackle these problems. MADP consists of some slot-dependent agents (S-Agents) and a slot-independent agent (G-Agent). S-Agents have shared parameters in addition to private parameters for each one. During policy transfer, the shared parameters in S-Agents and the parameters in G-Agent can be directly transferred to the agents in extended/new domain. Simulation experiments showed that MADP can significantly speed up the policy learning and facilitate policy adaptation. Lu Chen 0002, Zhi Chen 0006, Bowen Tan, Milica Gasic, Kai Yu 0004 |
ICASSP | 4 |
| 2016 | Finding more effective microsatellite markers for forensicsabstractPublished by the Combined DNA Index System (CODIS) program of the Federal Bureau of Investigation (FBI) in 1997, the 13 core short tandem repeat (STR) loci are widely adopted as genetic markers in forensic applications, e.g., identity testing and paternity testing. However, these loci may be biased and suffer from reduced sensitivities towards specific population groups. In addition, the rapid growth of entries in forensic databases raises the chance of random hits, which can cause false judgments of innocents as criminals. A solution to these problems is to introduce more effective STR markers. The availability of whole genome sequencing enables us to identify more reliable STR markers for forensic applications computationally. In this study, we proposed an algorithm to identify STR markers with high discriminative abilities from the next-generation sequencing (NGS) data. Our algorithm could select a customized set of loci for a given population with pre-specified discriminative thresholds. We have applied the method to 320 Chinese individuals from the 1,000 Genomes Project and obtained various numbers of loci, which were able to statistically identify an individual worldwide and had higher combined powers of discrimination (CPD) and combined probabilities of exclusion (CPE) than the existing CODIS 13 loci. For identity testing, the mean frequency of DNA profile (FDP) with the selected 11 STRs was smaller than that with CODIS 13 STRs by student's t-test. With more loci, much smaller FDPs were obtained. The database matching probabilities (DMP) for selected loci were also lower than that for CODIS 13 STRs in a database with 10 billion entries. Moreover, the selected loci were able to provide considerably low chance of random profile matches so that statistically no false judgments could occur. The selected loci also reduced the risk of random allele matches when doing the familial search, with lower random allele matching probabilities. In addition, the selected STRs were statistically better than CODIS STRs for paternity testing in our simulated data, with lower probabilities of false inclusions and exclusions. Bowen Tan, Zicheng Zhao, Shengbin Li, Shuaicheng Li 0001 |
BIBM | 1 |