Yan Qiang 0001

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50ranked-venue papers
3as first author
33since 2021 · last 2026
—ORCID · conflict

Domains — the database's venue-derived domains; a paper can count in several

Graphics, computer vision, multimedia, augmented reality and games · 15 · 8 since 2021Applied, interdisciplinary, general and emerging computing · 14 · 9 since 2021Artificial intelligence and machine learning · 11 · 1 first-author · 9 since 2021Systems, architecture and hardware · 5 · 5 since 2021Human-computer interaction and ubiquitous computing · 4 · 4 since 2021Computer networks · 2 · 1 first-authorTheory of computation · 2 · 1 first-authorDatabases, data management, data science and information retrieval · 1
YearPublicationVenuePosition
2026 Augmentation-invariant Learning Strategy via Data Augmentation for Improving Model Generalization
abstract
Data augmentation is an effective technique for regularizing deep networks, which helps to enhance the generalizability and robustness of the model. However, in the field of medical imaging, traditional data augmentation techniques such as cropping, rotation, and degradation may inadvertently alter the critical characteristics of pathological lesions. Conventional semantic augmentation methods, such as altering the color and contrast of the object background, may also affect the structural features of medical images in uncontrolled semantic directions. Such operational conditions compromise the model's diagnostic reliability in medical contexts. To address this issue, we propose a surprisingly efficient implicit augmentation-invariant learning strategy (AILS) via variational Bayesian inference on differentially constrained feature manifolds. Parameterizing probability measures over tangent space through deep networks enables precise estimation of semantic direction distributions. Subsequently, geodesic-aware semantic features are sampled from the reparameterized variational posterior, achieving semantic-consistent augmentation. Simultaneously, to mine augmentation distribution invariance, we design the AiHLoss, which constrains the augmentation distribution to facilitate the network to learn augmentation invariance. Extensive experiments demonstrate that AILS exhibits high performance on public medical image datasets, outperforming existing augmentation methods.
Juanjuan Zhao 0002, Sijie Song, Yuanqian Zhu, Lusha Qi, Yan Qiang 0001
AAAI7
2026 Learning-Augmented Cluster-Wise Prediction for Dynamic Multi-Objective Optimization
Yan Qiang 0001, Juanjuan Zhao 0002
PPSN (2)2
2026 Coordinating Challenge and Engagement: A Cross-Domain Virtual Reality Intervention with Adaptive Difficulty for Cognitive and Physical Enhancement in Cognitively Impaired Older Adults
abstract
As individuals age, simultaneous declines in cognitive function, physical ability, and visual capacity (e.g., dynamic visual acuity) pose challenges to maintaining functional independence in later life. Despite advances in immersive virtual environments for age-related functional support, dynamic visual acuity remains underexplored, particularly in relation to its interaction with cognitive and motor processes. Meanwhile, existing interventions often rely solely on performance-based difficulty adjustment, neglecting the dual need to maintain engagement and promote skill progression. To address these gaps, we developed the Pareto-based Dynamic Difficulty Adjustment for Cross-domain Co-training in Virtual Reality (CCVR-PDDA) system, integrating psychology paradigm (e.g., Stroop task), upper-limb motor training (e.g., arm lifting and raising), and dynamic visual exercises (e.g., multi-directional eye movements). A 12-week longitudinal study involving 60 older adults (≥65 years) demonstrated significant cognitive improvements, sustained at six-month follow-up. Qualitative feedback further supported the system’s usability, motivation enhancement, and long-term engagement potential. These findings underscore the efficacy and acceptability of CCVR-PDDA in promoting cognitive health in aging populations.
Aoyu Li, Yan Geng, Yan Qiang 0001, Juanjuan Zhao 0002
Int. J. Hum. Comput. Interact.4
2026 Spatial position association-based 3D CT reconstruction from biplanar X-rays
Yang Li 0010, Xueting Ren, Yan Qiang 0001, Juanjuan Zhao 0002, Huajie Yue
J. Vis. Commun. Image Represent.5
2025 DFEFNet: Dual Frequency Domain Enhanced Fusion by Physiological Synchronization for Facial Video-Based Physiological Measurement
abstract
Facial video-based physiological measurement primarily estimates heart rate by analyzing subtle skin color variations or global pixel motion patterns, which is a critical research direction of remote objective signal evaluation in human-computer interaction. However, accurate physiological signal extraction from facial videos remains challenging due to motion artifacts and large-scale motion interference. To address these issues, inspired by physiological synchronization phenomena, we propose a novel dual-domain perception enhanced fusion network for video-based physiological measurement. The model employs a dual-branch architecture that jointly explores the correlation and periodic consistency between intrinsic physiological processes and pixel-level facial variations through synchronized spectral skin reflectance analysis and extemporization motion modeling. The network extracts multi-semantic physiological features from facial video sequences, and introduces a spectral frequency attention module to refine discriminative frequency components in the spectral domain. Additionally, the local shift convolution module is designed to capture fine-grained global features in sparse temporal data via learnable shift operations, enhancing sensitivity to periodic physiological fluctuations. Furthermore, we propose a frequency complementary fusion mechanism, which adaptively retain and fuse high and low frequency components as-sociated with physiological signals. This fusion strategy strength-ens the relationship between latent physiological processes and multi-dimensional frequency-domain representations, improving measurement robustness and accuracy. Extensive experiments on multiple benchmark datasets demonstrate that our method achieves state-of-the-art performance in physiological signal es-timation.
Yishan Hu, Yan Qiang 0001, Juanjuan Zhao 0002, Baoping Jia
BIBM2
2025 EVLM-Net: Vision-Language Fusion with Efficient Upsampling for Accurate Polyp Segmentation
abstract
The Efficient Vision-Language Modulation Network (EVLM) aims to achieve accurate polyp segmentation, which is crucial for the early detection and prevention of colorectal cancer. However, the implementation of EVLM remains challenging due to the morphological differences, blurred boundaries, and complex visual background in colonoscopy images. Existing purely visual methods often fail to capture subtle contextual cues and lack the semantic guidance of clinical text, resulting in poor generalization performance across datasets. To overcome these limitations, we propose a novel EVLM that integrates BiomedCLIP text embeddings with SAM2-UNet via progressive, layer-by-layer feature linear modulation (FiLM). An efficient upconvolutional block (EUCB) is introduced to improve upsampling fidelity and boundary reconstruction. Comprehensive evaluation on three benchmark datasets (CVC-ClinicDB, Kvasir-SEG, and CVC-300) demonstrates that EVLM achieves superior performance, achieving mDice scores of 94%, 91.8%, and 89.5 %, respectively, consistently outperforming state-of-the-art methods. These findings highlight the potential of EVLM in real-time clinical deployment to provide robust and accurate polyp segmentation, thereby supporting enhanced colorectal cancer screening and early intervention.
Jiangpeng Shi, Lina Pang, Juanjuan Zhao 0002, Yan Qiang 0001
BIBM4
2025 RM-SSNet: An Ultra-Lightweight Medical Image Segmenter With Recursive Multi-Scale Reasoning and Boundary Enhancement
abstract
Deploying deep segmentation models in clinical settings is hindered by their excessive computational demands, which exceed the capabilities of mobile and edge devices widely used in low-resource healthcare. We propose RM-SSNet, an ultra-lightweight medical image segmentation framework that achieves 2,612 parameters-a 99.97 % reduction compared to standard UNet-while maintaining competitive accuracy. First, a recursive multi-scale pyramid architecture reuses identical transformation functions across different spatial resolutions, achieving multiresolution modeling capabilities while maintaining efficient parameter sharing. Second, a dynamic state space fusion module captures long-range spatial dependencies with linear computational complexity, replacing the quadratic complexity of traditional attention mechanisms. Third, a boundary-aware knowledge-guided refinement mechanism leverages parameterfree classical edge detection combined with learnable anatomical constraints to enhance segmentation precision without additional computational overhead. This integrated design enables clinically viable accuracy across multiple medical imaging datasets, including skin lesions, breast ultrasound, and retinal images. The framework supports real-time segmentation on mobile devices, making advanced AI-assisted diagnostic screening accessible in low-resource clinical settings.
Jiangpeng Shi, Juanjuan Zhao 0002, Yan Qiang 0001
BIBM3
2025 A Segmentation-Based Spatial Continuity Intensifying State Space Model for KRAS Mutation Identification in Colorectal Cancer
Sijie Song, Yulan Ma, Wensong Yue, Yan Qiang 0001, Juanjuan Zhao 0002
ICIC (14)5
2025 DTI Prediction Based on Lightweight MoE
Fang Zheng 0021, Juanjuan Zhao 0002, Yan Qiang 0001, Zihang Yuan, Yaheng Li, Yan Geng, Yifang Zheng, Yuanchen Gao
ICIC (25)3
2025 Anatomy-Based Self-supervised Pre-training for Scale-Robust Hierarchical Representations in Chest X-Rays
Surong Chu, Yan Qiang 0001, Guohua Ji, Xueting Ren, Baoping Jia, Yangyang Wei, Juanjuan Zhao 0002, Shuo Li 0001
MICCAI (10)2
2025 UM-DNA: A Unified Memory Bank for Discerning Near-Distribution Anomaly in Industrial Anomaly Detection and Localization
Yang Li 0010, Yishan Hu, Meiling Cai, Yan Qiang 0001, Juanjuan Zhao 0002
PRCV (4)7
2025 SFPM2: Industrial Visual Anomaly Localization with Spatial-Frequency Dual-Domain Parallel Mamba Network
Juanjuan Zhao 0002, Yishan Hu, Yang Li 0010, Chan Yi, Yan Qiang 0001
PRCV (16)6
2025 An Echo Pressure Model Based on Mutil-Gaussian Beam Theory for Measuring the Liquid Level in Special Field
abstract
ABSTRACT In aviation, petroleum and chemical industries and other special areas of production, since the liquid in containers mostly are flammable, explosive, volatile, and corrosive mixtures, the accurate measurement of the liquid level is essential to the real‐time control and production process. In this study, an approximation algorithm based on echo pressure model for measuring the liquid level in special field is proposed in this paper. According to the model, a complete lateral incident ultrasonic measurement system is constructed for the inductive liquid level detection technology in special applications, an algorithm model of the echo pressure is established, which provides the determination of the liquid level relying on the characteristic curve of the echo pressure. The model in this study converts complex interaction problems of sound fields into the echo pressure calculation, which quickly determines performance parameters of sound fields, and a virtual reflection method is used to calculate the sound pressure of the receiving transducer in different states, which reduces computational complexity, finally, through the simulation and experiment, the algorithm is validated. The results are consistent with expectations, and the algorithm can be further applied in practice.
Yue-Juan Wei, Shuqui Zang, Qing Li 0078, Yan Qiang 0001
Concurr. Comput. Pract. Exp.5
2025 Frequency domain nuances guided parallel transformer model for industrial anomaly localization
Kaixuan Yu, Yingsen Wang, Juanjuan Zhao 0002, Yan Qiang 0001, Bo Pei
Eng. Appl. Artif. Intell.8
2025 Unearthing Subtle Cognitive Variations: A Digital Screening Tool for Detecting and Monitoring Mild Cognitive Impairment
abstract
Early diagnosis of mild cognitive impairment (MCI) is pivotal in mitigating the risk of cognitive impairment and the onset of dementia. However, prevailing clinical cognitive screening tests and biomarker assessment approaches often suffer from drawbacks such as high cost, invasiveness, time consumption, or subjectivity. In China, existing digital cognitive assessment tools face multiple challenges due to their distinctive cultural, language, and healthcare landscape. Therefore, we embarked on a study to develop a digital cognitive assessment tool, evaluate its efficacy in distinguishing between healthy individuals and MCI patients, and examine its acceptability among Chinese older adults. Through a series of symposiums, programming, and interviews with stakeholders, we iteratively designed the "BrainNursing" mobile application. The system consists of eleven single tasks and three dual tasks, each taking only 1–3 minutes. Subsequently, we conducted statistical comparisons of movement kinetics and physiological signals recorded during cognitive testing in 181 older adults to investigate which parameters could serve as effective digital biomarkers for MCI screening. Leveraging machine learning classifiers and a majority voting principle, we evaluated the classification performance of the BrainNursing system in detecting MCI, yielding an accuracy rate of 90.3%. Furthermore, our analysis of movement kinetics revealed that time, score, and sequence features are crucial in cognitive assessment. Contrasting with their healthy counterparts, MCI patients exhibited decreased heart rate variability, increased sympathetic nervous system activity, and weakened autonomic nervous system regulation in response to stimuli during cognitive testing. Finally, user experience feedback indicated that participants universally perceived BrainNursing as a convenient and user-friendly cognitive screening tool and provided valuable insights for further improvement.
Aoyu Li, Ruixuan Wu, Wei Wu 0061, Juanjuan Zhao 0002, Yan Qiang 0001
Int. J. Hum. Comput. Interact.6
2025 VC-Mamba: Causal Mamba representation consistency for video implicit understanding
Yishan Hu, Chen Qi, Yan Qiang 0001, Juanjuan Zhao 0002, Bo Pei
Knowl. Based Syst.4
2025 Dual-Domain Optimization Model Based on Discrete Fourier Transform and Frequency-Domain Fusion for Remote Sensing Single-Image Super-Resolution
abstract
Deep neural network models generally enhance super-resolution (SR) reconstruction of remote sensing images but may distort feature edge details. Recovering low-resolution (LR) remote sensing images with clear texture and high-fidelity edge details is challenging. Recent approaches improve feature fusion in the frequency domain, yielding promising results. We propose a dual-domain optimization network (DDOM) based on discrete Fourier transform (DFT) and frequency-domain complex-valued neural networks. Unlike end-to-end approaches in the image domain, DDOM incorporates frequency-domain information via DFT transformation operators, preserving high-level semantics (phase) and low-level statistical information (magnitude). Using lightweight complex neural networks and Swin Transformer architecture, the frequency-domain and image-domain subnetworks are designed. The dual-domain data consistency constraints ensure the positivity of model optimization. Extensive experiments show superior performance over existing methods in quantitative and qualitative evaluations. The proposed scheme’s robustness is verified on additional datasets. Code and model configurations are available athttp://github.com/YB-Cheng/DDOM.
Yubin Cheng, Runrui Li, Hexi Wang, Yan Qiang 0001, Juanjuan Zhao 0002
IEEE Trans. Geosci. Remote. Sens.6
2025 Learning Consistent Semantic Representation for Chest X-ray via Anatomical Localization in Self-Supervised Pre-Training
abstract
Despite the similar global structures in Chest X-ray (CXR) images, the same anatomy exhibits varying appearances across images, including differences in local textures, shapes, colors, etc. Learning consistent representations for anatomical semantics through these diverse appearances poses a great challenge for self-supervised pre-training in CXR images. To address this challenge, we propose two new pre-training tasks: inner-image anatomy localization (IIAL) and cross-image anatomy localization (CIAL). Leveraging the relatively stable positions of identical anatomy across images, we utilize position information directly as supervision to learn consistent semantic representations. Specifically, IIAL adopts a coarse-to-fine heatmap localization approach to correlate anatomical semantics with positions, while CIAL leverages feature affine alignment and heatmap localization to establish a correspondence between identical anatomical semantics across varying images, despite their appearance diversity. Furthermore, we introduce a unified end-to-end pre-training framework, anatomy-aware representation learning (AARL), integrating IIAL, CIAL, and a pixel restoration task. The advantages of AARL are: 1) preserving the appearance diversity and 2) training in a simple end-to-end way avoiding complicated preprocessing. Extensive experiments on six downstream tasks, including classification and segmentation tasks in various application scenarios, demonstrate that our AARL: 1) has more powerful representation and transferring ability; 2) is annotation-efficient, reducing the demand for labeled data and 3) improves the sensitivity to detecting various pathological and anatomical patterns.
Surong Chu, Xueting Ren, Guohua Ji, Juanjuan Zhao 0002, Jinwei Shi, Yangyang Wei, Bo Pei, Yan Qiang 0001
IEEE J. Biomed. Health Informatics8
2025 An interpretable two-branch network based on an prototype to promote group gene biomarkers discovery
Fang Zheng 0021, Juanjuan Zhao 0002, Yuanchen Gao, Yaheng Li, Yan Geng, Yan Qiang 0001, Yifang Zheng
J. Supercomput.7
2024 CHNet: A multi-task global-local Collaborative Hybrid Network for KRAS mutation status prediction in colorectal cancer
Meiling Cai, Lin Zhao 0018, Yan Qiang 0001, Juanjuan Zhao 0002
Artif. Intell. Medicine3
2024 MFSynDCP: multi-source feature collaborative interactive learning for drug combination synergy prediction
abstract
Drug combination therapy is generally more effective than monotherapy in the field of cancer treatment. However, screening for effective synergistic combinations from a wide range of drug combinations is particularly important given the increase in the number of available drug classes and potential drug-drug interactions. Existing methods for predicting the synergistic effects of drug combinations primarily focus on extracting structural features of drug molecules and cell lines, but neglect the interaction mechanisms between cell lines and drug combinations. Consequently, there is a deficiency in comprehensive understanding of the synergistic effects of drug combinations. To address this issue, we propose a drug combination synergy prediction model based on multi-source feature interaction learning, named MFSynDCP, aiming to predict the synergistic effects of anti-tumor drug combinations. This model includes a graph aggregation module with an adaptive attention mechanism for learning drug interactions and a multi-source feature interaction learning controller for managing information transfer between different data sources, accommodating both drug and cell line features. Comparative studies with benchmark datasets demonstrate MFSynDCP's superiority over existing methods. Additionally, its adaptive attention mechanism graph aggregation module identifies drug chemical substructures crucial to the synergy mechanism. Overall, MFSynDCP is a robust tool for predicting synergistic drug combinations. The source code is available from GitHub at https://github.com/kkioplkg/MFSynDCP .
Yunyun Dong, Yunqing Chang, Qixuan Han, Xiaoyuan Wen, Ziting Yang, Yan Qiang 0001, Kun Wu 0005, Xiaole Fan, Xiaoqiang Ren
BMC Bioinform.8
2024 Effect of Virtual Reality Training on Cognitive Function and Motor Performance in Older Adults With Cognitive Impairment Receiving Health Care: A Randomized Controlled Trial
abstract
Given the prevalence of cognitive impairment in older adults and its frequent misdiagnosis or delayed diagnosis, non-pharmacological interventions have been proposed as solutions, which include cognitive training, prevention or risk reduction of dementia using virtual reality (VR) technology. This study aimed to investigate the effects of a virtual reality cognitive-motor training intervention (VRCMTI) on improving cognitive and physical function in older adults with cognitive impairment. We co-designed the VRCMTI system with multiple stakeholders by organizing symposiums and conducting pilot evaluations. The VRCMTI consisted of three virtual cognitive tasks and three upper limb movement tasks focused on improving working memory, spatial cognition, attention shifting, executive control, joint flexibility, and coordination. One hour of brain cognition and upper limb motor training was performed each week during the 12-week intervention. Sixty older adults were included in the study and randomly assigned to either the VR group or the control group. Participants in the control group received usual care and would not undergo any intervention training. Task independence, accuracy and time were measured during each session. The results showed that the VR group significantly improved global cognitive ability scores compared to the control group, especially in attention and verbal cognition. In addition, older adults in the VR group also showed significant improvements in upper limb motor skills, driven primarily by movement quality and processing speed. The findings suggest that VRCMTI could improve cognitive function and enhance motor performance. When implemented with routine health care for older adults, this practical and effective intervention may be an appropriate complementary strategy for maintaining cognitive health and preventing motor deterioration.
Aoyu Li, Wei Wu 0061, Juanjuan Zhao 0002, Yan Qiang 0001
Int. J. Hum. Comput. Interact.5
2024 VRNPT: A Neuropsychological Test Tool for Diagnosing Mild Cognitive Impairment Using Virtual Reality and EEG Signals
abstract
Mild cognitive impairment is associated with many neurodegenerative diseases. It is essential to detect mild cognitive impairment on time to reduce the prevalence of such disorders. Nevertheless, present clinically employed test scales and biomarkers are time-consuming, user-unfriendly, and expensive. Hence, we developed a neuropsychological test system based on virtual reality in this study, the Virtual Reality Neuropsychological Mild Cognitive Impairment Test (VRNPT). The diagnosis and classification of MCI were achieved by effectively combining digital cognitive parameters and EEG signal features obtained during the VRNPT cognitive task. The VRNPT contains three head-mounted display-based cognitive tasks that assess participants’ attention, memory, spatial perception, working memory, and visuospatial executive ability across multiple cognitive domains of functioning. We investigated how to design and optimize these tasks. We conducted a field study by recruiting 80 participants (40 MCI patients and 40 normal older adults). The results showed that the classification accuracy of combining digitized cognitive parameters and EEG signals during VRNPT was 91.3%, higher than using only digitized parameters from VRNPT and applying EEG signals alone, demonstrating the validity and feasibility of this method for diagnosing MCI. The user satisfaction survey showed that the subjects were satisfied with VRNPT.
Aoyu Li, Ruixuan Wu, Jiali Chai, Yan Qiang 0001, Juanjuan Zhao 0002
Int. J. Hum. Comput. Interact.5
2023 A segmentation-based sequence residual attention model for KRAS gene mutation status prediction in colorectal cancer
Lin Zhao 0018, Kai Song 0004, Yulan Ma, Meiling Cai, Yan Qiang 0001, Jingyu Sun, Juanjuan Zhao 0002
Appl. Intell.5
2023 Deep learning approach for predicting lymph node metastasis in non-small cell lung cancer by fusing image-gene data
Guojie Hou, Liye Jia, Wei Wu 0061, Lin Zhao 0018, Juanjuan Zhao 0002, Yan Qiang 0001
Eng. Appl. Artif. Intell.8
2023 Residual neural network with mixed loss based on batch training technique for identification of EGFR mutation status in lung cancer
Liye Jia, Wei Wu 0061, Guojie Hou, Juanjuan Zhao 0002, Yan Qiang 0001, Meiling Cai
Multim. Tools Appl.5
2022 DAS-Net: A lung nodule segmentation method based on adaptive dual-branch attention and shadow mapping
Shichao Luo, Jina Zhang, Yan Qiang 0001, Keqin Li 0001, Juanjuan Zhao 0002
Appl. Intell.4
2022 BAC: A block alliance consensus mechanism for the mine consortium blockchain
abstract
Abstract Safety is an important issue in the mining industry and the Internet of Things (IoT) plays an important role to enhance the safety of the underground working environment. The IoT is used to transfer data generated by underground sensors to cloud storage for further processing. However, third‐party platforms are often a target for cyber attacks. Serious mining accidents might occur if the data were tampered with. In the overground scenario, the security of trading data is also an important issue. The Mine Consortium Blockchain (MCB) is proposed to solve the above problems. The MCB avoids the risk of centralized storage and enables data security, provenance and transparency by taking advantage of blockchain technology. The MCB platform ensures that only designated participants can process mineral data. Any violation is immutably recorded in the MCB and is easily traced back by other participants. Classical consensus mechanisms as the core technology of the blockchain cannot be directly and appropriately applied to the mining industry. A Block Alliance Consensus (BAC) mechanism, which is suitable for all consortium blockchain scenarios, is proposed to improve the performance of the MCB. In addition, the block structure of the underground sensor data is optimized: the blocks only contain a hash of the sensor data and the data being stored in the cloud. The efficiency of the BAC is demonstrated by simulation experiments where the performance of the BAC consensus mechanism is compared with with the performance of classical consensus mechanisms. The MCB and the BAC consensus mechanism were also implemented on Hyperledger Fabric. Finally the Hyperledger Caliper evaluation tool was used to evaluate the performance of the system.
Yingsen Wang, Yulan Ma, Yan Qiang 0001, Juanjuan Zhao 0002, Yi Li 0081, Keqin Li 0001
Concurr. Comput. Pract. Exp.3
2022 Improved heterogeneous data fusion and multi-scale feature selection method for lung cancer subtype classification
abstract
Summary The diagnosis of the disease requires a variety of data and indicators. In order to make the computer perform intelligent computation and diagnosis from a doctor's perspective, complementary information between different modal data needs to be taken into account. Meanwhile, the redundancy features with key information should be selected in order to reduce the complexity of calculation. In this study, an adaptive dynamic loss function is proposed to weight different scales in the multi‐scale expansion network of pathological images according to the doctor's diagnosis process. And an ant colony algorithm based on maximum information coefficient correlation was designed for unsupervised feature selection of fusion features combined image feature and patient differential genes. Experimental results show that the addition of pathological image information and genetic information plays an important role in the classification of lung cancer subtypes. Compared with other feature selection methods, the proposed algorithm can quickly converge. Combining pathological image and gene expression matrix for cancer diagnosis can improve the diagnostic accuracy of specific patients, with an accuracy of 95.62 and AUC achieves 0.897. The proposed method has high effectiveness and superior performance in the classification of lung cancer.
Juanjuan Zhao 0002, Yan Qiang 0001, Xiaotang Yang, Wei Wu 0061, Liye Jia
Concurr. Comput. Pract. Exp.3
2022 Multi-level learning based on 3D CT image integrated medical clinic information for accurate diagnosis of pulmonary nodules
abstract
Abstract The diagnosis of pulmonary nodules by clinicians depends not only on radiological imaging but also on the patient's own clinical record information and other factors. However, exploring the guiding role of clinical information is a major challenge. In this article, an intelligent personalized diagnosis decision‐making model is proposed, which combines radiology images with patient information. First, the 3D image cube of the pulmonary nodule is constructed. Then, a 3D multi‐level fusion ResNet is designed to extract the features of the nodule by making full use of the spatial context information. Finally, a kind of classification model based on feature‐related analysis was proposed, which fused clinical information features and image features and realized a nonlinear radial basis feature mapping. We tested this method on the public dataset and a cooperation hospital dataset. Experiments show that this method can effectively improve the classification accuracy of unstable nodules at the classification boundary. Our model showed significant improvements in sensitivity, specificity, and accuracy. Meanwhile, compared with other deep learning diagnosis methods, our method achieves better discriminative results and is highly suited to be used for pulmonary nodule diagnosis.
Juanjuan Zhao 0002, Wei Wu 0061, Yan Qiang 0001, Liye Jia
Concurr. Comput. Pract. Exp.4
2021 DPACN: Dual Prior-Guided Astrous Convolutional Network for Adhesive Pulmonary Nodules Segmentation on CT Sequence
Shichao Luo, Yan Qiang 0001, Juanjuan Zhao 0002, Jianhong Lian
PRCV (3)3
2021 Integrate domain knowledge in training multi-task cascade deep learning model for benign-malignant thyroid nodule classification on ultrasound images
Wenkai Yang, Yunyun Dong, Yan Qiang 0001, Kun Wu 0005, Juanjuan Zhao 0002, Xiaotang Yang, Muhammad Bilal Zia
Eng. Appl. Artif. Intell.4
2021 DART: a visual analytics system for understanding dynamic association rule mining
Yan Qiang 0001, Juanjuan Zhao 0002, Jiangyang Xu, Xiaobo Fan, Yemin Yang, Xiaolong Zhang 0001
Vis. Comput.3
2020 Multi-branch cross attention model for prediction of KRAS mutation in rectal cancer with t2-weighted MRI
Yanfen Cui, Guohua Shi, Juanjuan Zhao 0002, Xiaotang Yang, Yan Qiang 0001, Ntikurako Guy-Fernand Kazihise
Appl. Intell.6
2020 DRGAN: a deep residual generative adversarial network for PET image reconstruction
abstract
Positron emission tomography (PET) image reconstruction from low‐count projection data and physical effects is challenging because the inverse problem is ill‐posed and the resultant image is usually noisy. Recently, generative adversarial networks (GANs) have also shown their superior performance in many computer vision tasks and attracted growing interests in medical imaging. In this work, the authors proposed a novel model [deep residual generative adversarial network (DRGAN)] based on GANs for the reduction of streaking artefacts and the improvement of PET image quality. An innovative feature of the proposed method is that the authors trained a generator to produce ‘residual PET map’ (RPM) for image representation, rather than generate PET images directly. DRGAN used two discriminators (critics) to enforce anatomically realistic PET images and RPM. To better boost the contextual information, the authors designed residual dense connections followed with pixel shuffle operations (RDPS blocks) that encourage feature reuse and prevent losing resolution. Both simulation data and real clinical PET data are used to evaluate the proposed method. Compared with other state‐of‐the‐art methods, the quantification results show that DRGAN can achieve better performance in bias–variance trade‐off and provide comparable image quality. Their results were rigorously evaluated by one radiologist at the Shanxi Cancer Hospital.
Yan Qiang 0001, Wenkai Yang, Muhammad Bilal Zia
IET Image Process.2
2020 Iterative PET image reconstruction using cascaded data consistency generative adversarial network
abstract
This study proposed a GAN‐based reconstruction method‐cascaded data consistency generative adversarial network (CDCGAN) to recover high‐quality PET images from filtered back projection PET images with streaking artifacts and high noise. First, the authors embed defined data consistency layer (DC layer) in their generator network to constrain the reconstruction process and adjust accurately generated faked PET images. Second, to improve the accuracy of reconstruction on average, their generator network was built iteratively to achieve better performance with simple structures. They observed that the proposed CDCGAN allows the preservation of fine anomalous features while eliminating the streaking artifacts and noise. Experimental results show that the reconstructed PET images by their methods perform well comparably to other state‐of‐the‐art methods but at a faster speed. A clinical experiment was also performed to show the validity of the CDCGAN for artifacts reduction.
Xueting Ren, Yan Qiang 0001, Xiaotang Yang, Ntikurako Guy-Fernand Kazihise
IET Image Process.4
2020 Tumour growth prediction of follow-up lung cancer via conditional recurrent variational autoencoder
abstract
The prediction of lung tumour growth is the key to early treatment of lung cancer. However, the lack of intuitive and clear judgments about the future development of the tumour often leads patients to miss the best treatment opportunities. Combining the characteristics of the variational autoencoder and recurrent neural networks, this study proposes a tumour growth prediction via a conditional recurrent variational autoencoder. The proposed model uses a variational autoencoder to reconstruct tumour images at different times. Meanwhile, the recurrent units are proposed to infer the relationship between tumour images according to the chronological order. The different tumour development varies in different patients, patients' condition is adopted to achieve personalised prediction. To solve the problem of blurred results, the authors add the total variation regularisation term into the object function. The proposed method was tested on longitudinal studies, National Lung Screening Trial and cooperative hospital dataset, with three points on lung tumours. The precision, recall, and dice similarity coefficient reach 82.22, 79.89 and 82.49%, respectively. Both quantitative and qualitative experimental results show that the proposed method can produce realistic tumour images.
Yan Qiang 0001, Zijuan Zhao, Juanjuan Zhao 0002, Jianhong Lian
IET Image Process.2
2020 An improved supervoxel 3D region growing method based on PET/CT multimodal data for segmentation and reconstruction of GGNs
Yunyun Dong, Wenkai Yang, Zijuan Zhao, Sanhu Wang, Yan Qiang 0001
Multim. Tools Appl.7
2019 Radiomics-guided GAN for Segmentation of Liver Tumor Without Contrast Agents
Xiaojiao Xiao, Juanjuan Zhao 0002, Yan Qiang 0001, Jaron Chong, Xiaotang Yang, Ntikurako Guy-Fernand Kazihise, Bo Chen 0013, Shuo Li 0001
MICCAI (2)3
2019 DScGANS: Integrate Domain Knowledge in Training Dual-Path Semi-supervised Conditional Generative Adversarial Networks and S3VM for Ultrasonography Thyroid Nodules Classification
Wenkai Yang, Juanjuan Zhao 0002, Yan Qiang 0001, Xiaotang Yang, Yunyun Dong, Guohua Shi, Muhammad Bilal Zia
MICCAI (4)3
2019 MLW-gcForest: a multi-weighted gcForest model towards the staging of lung adenocarcinoma based on multi-modal genetic data
abstract
BACKGROUND: Lung cancer is one of the most common types of cancer, among which lung adenocarcinoma accounts for the largest proportion. Currently, accurate staging is a prerequisite for effective diagnosis and treatment of lung adenocarcinoma. Previous research has used mainly single-modal data, such as gene expression data, for classification and prediction. Integrating multi-modal genetic data (gene expression RNA-seq, methylation data and copy number variation) from the same patient provides the possibility of using multi-modal genetic data for cancer prediction. A new machine learning method called gcForest has recently been proposed. This method has been proven to be suitable for classification in some fields. However, the model may face challenges when applied to small samples and high-dimensional genetic data. RESULTS: In this paper, we propose a multi-weighted gcForest algorithm (MLW-gcForest) to construct a lung adenocarcinoma staging model using multi-modal genetic data. The new algorithm is based on the standard gcForest algorithm. First, different weights are assigned to different random forests according to the classification performance of these forests in the standard gcForest model. Second, because the feature vectors generated under different scanning granularities have a diverse influence on the final classification result, the feature vectors are given weights according to the proposed sorting optimization algorithm. Then, we train three MLW-gcForest models based on three single-modal datasets (gene expression RNA-seq, methylation data, and copy number variation) and then perform decision fusion to stage lung adenocarcinoma. Experimental results suggest that the MLW-gcForest model is superior to the standard gcForest model in constructing a staging model of lung adenocarcinoma and is better than the traditional classification methods. The accuracy, precision, recall, and AUC reached 0.908, 0.896, 0.882, and 0.96, respectively. CONCLUSIONS: The MLW-gcForest model has great potential in lung adenocarcinoma staging, which is helpful for the diagnosis and personalized treatment of lung adenocarcinoma. The results suggest that the MLW-gcForest algorithm is effective on multi-modal genetic data, which consist of small samples and are high dimensional.
Yunyun Dong, Wenkai Yang, Juanjuan Zhao 0002, Yan Qiang 0001, Zijuan Zhao, Ntikurako Guy-Fernand Kazihise, Yanfen Cui
BMC Bioinform.5
2019 A feature extraction method for lung nodules based on a multichannel principal component analysis network (PCANet)
Xiaojiao Xiao, Zilin Qiang, Juanjuan Zhao 0002, Yan Qiang 0001, Pan Wang 0014
Multim. Tools Appl.4
2018 Double Attention Mechanism for Sentence Embedding
Miguel Kakanakou, Hongwei Xie, Yan Qiang 0001
WISA3
2017 A Bird Flock Gravitational Search Algorithm Based on the Collective Response of Birds
abstract
Gravitational search algorithm (GSA) is a stochastic search algorithm based on the law of gravity and mass which is widely used nowadays for efficient solution of optimization problems. For the purpose of enhancing the performance of original GSA, this paper proposes a new GSA called Bird Flock Gravitational Search Algorithm (BFGSA) based on the collective response of birds. Although GSA performs well in many problems, algorithms in this category lack mechanisms which add diversity to exploration in the search process. Our proposed algorithm introduces a new mechanism into GSA to add diversity, a mechanism which is inspired by the collective response behavior of birds. This mechanism performs its diversity enhancement through three main major steps including initialization, identification of the nearest neighbors and orientation change. The initialization is to generate candidate populations for the second steps and the orientation change updates the position of objects based on the nearest neighbors. Due to the collective response mechanism, the BFGSA explores a wider range of the search space and thus escapes suboptimal solutions. The efficiency and robustness of the proposed algorithm is demonstrated using multiple traditional and newly composed benchmark functions presented in CEC2005 competition and the results are compared with recent variants of the original particle swarm optimization and state-of-the-art GSA algorithms. Furthermore, we applied BFGSA to a real-world application of data clustering. The results show that BFGSA improves the performance of the original GSA and obtains the best results compared with our selected GSA-type algorithms in benchmarking experiments and clustering experiments.
XiaoHong Han, Yan Qiang 0001, Yuan Lan
Comput. J.2
2017 Pulmonary nodule diagnosis using dual-modal supervised autoencoder based on extreme learning machine
abstract
Abstract In recent years, deep learning techniques have been applied to the diagnosis of pulmonary nodules. In order to improve the pulmonary nodule diagnostic performance effectively, we propose a novel pulmonary nodule diagnosis method using dual‐modal deep supervised autoencoder based on extreme learning machine for which discriminative features are automatically learnt from the input data. The network is fed with nodule images in pairs obtained from computed tomography and positron emission tomography respectively. For each pair image, the high‐level discriminative features of nodules in computed tomography and positron emission tomography are extracted from stacked supervised autoencoder layers. The outputs of the proposed architecture are combined using an ideal fusion method to get the final classification. In the experiments, 5‐fold cross‐validation method is used to validate the proposed method on 1,600 pulmonary nodule images and our method reaches high‐classification sensitivities of 91.75% at 1.58 false positives per scan. Meanwhile, compared with other deep learning diagnosis methods, our method achieves better discriminative results and is highly suited to be used for pulmonary nodule diagnosis.
Yan Qiang 0001, Xiaolong Zhang 0001, Xiaoxian Tang
Expert Syst. J. Knowl. Eng.1
2016 An automated pulmonary parenchyma segmentation method based on an improved region growing algorithmin PET-CT imaging
Juanjuan Zhao 0002, Guohua Ji, XiaoHong Han, Yan Qiang 0001, Xiaolei Liao
Frontiers Comput. Sci.4
2014 A New Energy Reduction Method Based on Fire Probability Threshold Switch for WSN
abstract
To solve the energy limitation problems of wireless sensor networks used in forest fire detection applications, a new algorithm based on a fire probability threshold switch is proposed. The method uses the weighted average method to obtain the weights of each sensor node, and then calculates the fire probability for each node based on a logistic regression to obtain the fire probability threshold, based on this, the numbers of sensor nodes sending data to the sink node are obtained. The proposed algorithm is applied to detection of a wood fire in a simulated situation. The results show that the proposed method reduced the transmission energy used by 34%. These results indicate that the method can reduce the unnecessary energy usage effectively while guaranteeing the reliability of the transmission data.
Yan Qiang 0001, Xiaomin Chang, Juanjuan Zhao 0002, Xiaolong Zhang 0001, Xiaofei Yan
MSN1
2014 Multisensor Data Fusion for Wildfire Warning
abstract
Wildfires are highly destructive disasters that spread quickly. The use of advanced technology to achieve early warnings of wildfires is essential for the protection of wilderness resources. Nowadays, the method of using wireless sensor networks for wildfire warning has been extensively studied by many researchers. In this paper, we propose and have implemented a multi-sensor data fusion algorithm for wildfire monitoring and warning based on adaptive weighted fusion algorithm (AWFA) and Dempster -- Shafer theory (DST) of evidence. At the same time, we also have put forward some auxiliary algorithms for fire warning, including heterogeneous sensor data homogenization methods, a judgment algorithm for sensor numerical errors, and an evidence conflict solution of Dempster -- Shafer theory of evidence. Experimental results show that this algorithm can ensure the timeliness and accuracy of the wildfire warning, effectively reduce the amount of data transmission of sensor nodes and the whole network, and reduce the energy consumption, thus prolonging the network lifetime.
Juanjuan Zhao 0002, Yongxing Liu, Yongqiang Cheng 0003, Yan Qiang 0001, Xiaolong Zhang 0001
MSN4
2013 Social Network Path Analysis Based on HBase
Yan Qiang 0001, Junzuo Lu, Weili Wu 0001, Juanjuan Zhao 0002, Xiaolong Zhang 0001, Lidong Wu
COCOON1
2013 A Short-Term Prediction Model of Topic Popularity on Microblogs
Juanjuan Zhao 0002, Weili Wu 0001, Xiaolong Zhang 0001, Yan Qiang 0001, Lidong Wu
COCOON4