Makeup transfer involves transferring makeup from a reference image to a target image while maintaining the target’s identity. Existing methods, which use Generative Adversarial Networks, often transfer not just makeup but also the reference image’s skin tone. This limits their use to similar skin tones and introduces bias. Our solution introduces a skin tone-robust makeup embedding achieved by augmenting the reference image with varied skin tones. Using Graph Neural Networks, we establish connections between target, reference, and augmented images to create this robust representation that preserves the target’s skin tone. In a user study, our approach outperformed other methods 66% of the time, showcasing its resilience to skin tone variations.

Localization of anatomical landmarks to perform two-dimensional measurements in echocardiography is part of routine clinical workflow in cardiac disease diagnosis. Automatic localization of those landmarks is highly desirable to improve workflow and reduce interobserver variability. Training a machine learning framework to perform such localization is hindered given the sparse nature of gold standard labels; only few percent of cardiac cine series frames are normally manually labeled for clinical use. In this paper, we propose a new end-to-end reciprocal detection and tracking model that is specifically designed to handle the sparse nature of echocardiography labels. The model is trained using few annotated frames across the entire cardiac cine sequence to generate consistent detection and tracking of landmarks, and an adversarial training for the model is proposed to take advantage of these annotated frames. The superiority of the proposed reciprocal model is demonstrated using a series of experiments.

In echocardiography (echo), an electrocardiogram (ECG) is conventionally used to temporally align different cardiac views for assessing critical measurements. However, in emergencies or point-of-care situations, acquiring an ECG is often not an option, hence motivating the need for alternative temporal synchronization methods. Here, we propose Echo-SyncNet, a self-supervised learning framework to synchronize various cross-sectional 2D echo series without any human supervision or external inputs. The proposed framework takes advantage of two types of supervisory signals derived from the input data: spatiotemporal patterns found between the frames of a single cine (intra-view self-supervision) and interdependencies between multiple cines (inter-view self-supervision). The combined supervisory signals are used to learn a feature-rich and low dimensional embedding space where multiple echo cines can be temporally synchronized. Two intra-view self-supervisions are used, the first is based on the information encoded by the temporal ordering of a cine (temporal intra-view) and the second on the spatial similarities between nearby frames (spatial intra-view). The inter-view self-supervision is used to promote the learning of similar embeddings for frames captured from the same cardiac phase in different echo views. We evaluate the framework with multiple experiments: 1) Using data from 998 patients, Echo-SyncNet shows promising results for synchronizing Apical 2 chamber and Apical 4 chamber cardiac views, which are acquired spatially perpendicular to each other; 2) Using data from 3070 patients, our experiments reveal that the learned representations of Echo-SyncNet outperform a supervised deep learning method that is optimized for automatic detection of fine-grained cardiac cycle phase; 3) We go one step further and show the usefulness of the learned representations in a one-shot learning scenario of cardiac key-frame detection. Without any fine-tuning, key frames in 1188 validation patient studies are identified by synchronizing them with only one labeled reference cine. We do not make any prior assumption about what specific cardiac views are used for training, and hence we show that Echo-SyncNet can accurately generalize to views not present in its training set. Project repository: github.com/fatemehtd/Echo-SyncNet>.

Accurate detection of end-systolic (ES) and end-diastolic (ED) frames in an echocardiographic cine series can be difficult but necessary pre-processing step for the development of automatic systems to measure cardiac parameters. The detection task is challenging due to variations in cardiac anatomy and heart rate often associated with pathological conditions. We formulate this problem as a regression problem and propose several deep learning-based architectures that minimize a novel global extrema structured loss function to localize the ED and ES frames. The proposed architectures integrate convolution neural networks (CNNs)-based image feature extraction model and recurrent neural networks (RNNs) to model temporal dependencies between each frame in a sequence. We explore two CNN architectures: DenseNet and ResNet, and four RNN architectures: long short-term memory, bi-directional LSTM, gated recurrent unit (GRU), and Bi-GRU, and compare the performance of these models. The optimal deep learning model consists of a DenseNet and GRU trained with the proposed loss function. On average, we achieved 0.20 and 1.43 frame mismatch for the ED and ES frames, respectively, which are within reported inter-observer variability for the manual detection of these frames.