While foundation models have shown promise across a variety of fields, astronomy lacks a unified framework for joint modeling across its highly diverse data modalities. In this paper, we present AION-1, the first large-scale multimodal foundation family of models for astronomy. AION-1 enables arbitrary transformations between heterogeneous data types using a two-stage architecture: modality-specific tokenization followed by transformer-based masked modeling of cross-modal token sequences. Trained on over 200M astronomical objects, AION-1 demonstrates strong performance across regression, classification, generation, and object retrieval tasks. Beyond astronomy, AION-1 provides a scalable blueprint for multimodal scientific foundation models that can seamlessly integrate heterogeneous combinations of real-world observations. Our model release is entirely open source, including the dataset, training script, and weights.

In the natural sciences, a common challenge is to disentangle distinct, unknown sources from observations. Examples of this source separation task include deblending galaxies in a crowded field, distinguishing the activity of individual neurons from overlapping signals, and separating seismic events from the ambient background. Traditional analyses often rely on simplified source models that fail to accurately reproduce the data. Recent advances have shown that diffusion models can directly learn complex prior distributions from noisy, incomplete data. In this work, we show that diffusion models can solve the source separation problem without explicit assumptions about the source. Our method relies only on multiple views, or the property that different sets of observations contain different linear transformations of the unknown sources. We show that our method succeeds even when no source is individually observed and the observations are noisy, incomplete, and vary in resolution. The learned diffusion models enable us to sample from the source priors, evaluate the probability of candidate sources, and draw from the joint posterior of our sources given an observation. We demonstrate the effectiveness of our method on a range of synthetic problems as well as real-world galaxy observations.

JPEG is one of the most widely used image formats, but in some ways remains surprisingly unoptimized, perhaps because some natural optimizations would go outside the standard that defines JPEG. We show how to improve JPEG compression in a standard-compliant, backward-compatible manner, by finding improved default quantization tables. We describe a simulated annealing technique that has allowed us to find several quantization tables that perform better than the industry standard, in terms of both compressed size and image fidelity. Specifically, we derive tables that reduce the FSIM error by over 10% while improving compression by over 20% at quality level 95 in our tests; we also provide similar results for other quality levels. While we acknowledge our approach can in some images lead to visible artifacts under large magnification, we believe use of these quantization tables, or additional tables that could be found using our methodology, would significantly reduce JPEG file sizes with improved overall image quality.