The present paper investigates the trade‐offs between the energy efficiency (EE) and spectral efficiency (SE) in the full‐duplex (FD) multiuser multi‐input multioutput (MU‐MIMO) cloud radio access networks (CRANs) with simultaneous wireless information and power transfer (SWIPT). In the considered network, the central unit (CU) intends to concurrently not only transfer both energy and information toward downlink (DL) users using power splitting structures but also receive signals from uplink (UL) users. This communication is executed via FD radio units (RUs) which are distributed nearby users and connected to the CU through limited capacity fronthaul (FH) links. In order to unveil interesting trade‐offs between the EE and SE metrics, we first introduce three conventional single‐objective optimization problems (SOOPs) including (i) system sum rate maximization, (ii) total power minimization, and (iii) fractional energy efficiency maximization. Then, by making use of the multiobjective optimization (MOO) framework, the MOO problem (MOOP) with the objective vector of the achievable rate and power consumption is addressed. All considered problems are nonconvex with respect to designing variables comprising precoding matrices, compression matrices, and DL power splitting factors; thus, it is extremely intractable to solve these problems directly. To overcome these issues, we develop iterative algorithms by utilizing the sequential convex approximation (SCA) approach for the first two SOO problems and the SCA‐based Dinkelbach method for the fractional EE problem. Regarding the MOOP, we first rewrite it as an SOOP by applying the modified weighted Tchebycheff method and, then, propose the iterative algorithm‐based SCA to find its optimal Pareto set. Various numerical simulations are conducted to study the system performance and appealing EE‐SE trade‐offs in the considered system.