The existence of native code in Android apps plays an important role in triggering inconspicuous propagation of secrets and circumventing malware detection. However, the state-of-the-art information-flow analysis tools for Android apps all have limited capabilities of analyzing native code. Due to the complexity of binary-level static analysis, most static analyzers choose to build conservative models for a selected portion of native code. Though the recent inter-language analysis improves the capability of tracking information flow in native code, it is still far from attaining similar effectiveness of the state-of-the-art information-flow analyzers that focus on non-native Java methods. To overcome the above constraints, we propose a new analysis framework,$\mu$Dep, to detect sensitive information flows of the Android apps containing native code. In this framework, we combine a control-flow based static binary analysis with a mutation-based dynamic analysis to model the tainting behaviors of native code in the apps. Based on the result of the analyses,$\mu$Dep conducts a stub generation for the related native functions to facilitate the state-of-the-art analyzer DroidSafe with fine-grained tainting behavior summaries of native code. The experimental results show that our framework is competitive on the accuracy, and effective in analyzing the information flows in real-world apps and malware compared with the state-of-the-art inter-language static analysis.