Web attacks penetrate the web applications’ security through unauthorized access to sensitive information, disrupting services, and stealing data. Conventionally, rule-based statistical methods distinguish attackers from legitimate users. However, the training through manually extracted weblog features is time-consuming and requires subject expertise. Additionally, the supervised attack classification method needs massive, labeled weblog data, which is expensive and unfeasible. Also, the unsupervised classification techniques have resolved the labeled data insufficiency problem, but their detection performance is unreliable. Recent studies focus on recognizing web attacks through deep neural network-based anomaly detection. Hence, this study proposes an anomaly detection-based Variational LSTM Autoencoder Deviation Network (VLADEN) for recognizing web attacks from weblogs. This work resolves the aforementioned issues by extracting the aberrant information encoded in weblog request data to detect web attacks. VLADEN works in three stages: data preprocessing, anomaly and reference score generation, and classification. The variational LSTM self-encoding-based reference score generation ensures that the anomaly score deviates from the normal data. The proposed model is experimentally validated on three publicly available datasets (CSIS2010, FWAF, and HTTPParams) and evaluated using AUC-ROC and AUC-PR-based evaluation metrics. The results demonstrate the models’ superior performance in detecting attack requests with minimum domain knowledge and labeled data.

Automated classification of breast cancer can often save lives, as manual detection is usually time-consuming & expensive. Since the last decade, deep learning techniques have been most widely used for the automatic classification of breast cancer using histopathology images. This paper has performed the binary and multi-class classification of breast cancer using a transfer learning-based ensemble model. To analyze the correctness and reliability of the proposed model, we have used an imbalance IDC dataset, an imbalance BreakHis dataset in the binary class scenario, and a balanced BACH dataset for the multi-class classification. A lightweight shallow CNN model with batch normalization technology to accelerate convergence is aggregated with lightweight MobileNetV2 to improve learning and adaptability. The aggregation output is fed into a multilayer perceptron to complete the final classification task. The experimental study on all three datasets was performed and compared with the recent works. We have fine-tuned three different pre-trained models (ResNet50, InceptionV4, and MobilNetV2) and compared it with the proposed lightweight ensemble model in terms of execution time, number of parameters, model size, etc. In both the evaluation phases, it is seen that our model outperforms in all three datasets.

The explosion of the high-dimensional dataset in the scientific repository has been encouraging interdisciplinary research on data mining, pattern recognition and bioinformatics. The fundamental problem of the individual Feature Selection (FS) method is extracting informative features for classification model and to seek for the malignant disease at low computational cost. In addition, existing FS approaches overlook the fact that for a given cardinality, there can be several subsets with similar information. This paper introduces a novel hybrid FS algorithm, called Filter-Wrapper Feature Selection (FWFS) for a classification problem and also addresses the limitations of existing methods. In the proposed model, the front-end filter ranking method as Conditional Mutual Information Maximization (CMIM) selects the high ranked feature subset while the succeeding method as Binary Genetic Algorithm (BGA) accelerates the search in identifying the significant feature subsets. One of the merits of the proposed method is that, unlike an exhaustive method, it speeds up the FS procedure without lancing of classification accuracy on reduced dataset when a learning model is applied to the selected subsets of features. The efficacy of the proposed (FWFS) method is examined by Naive Bayes (NB) classifier which works as a fitness function. The effectiveness of the selected feature subset is evaluated using numerous classifiers on five biological datasets and five UCI datasets of a varied dimensionality and number of instances. The experimental results emphasize that the proposed method provides additional support to the significant reduction of the features and outperforms the existing methods. For microarray data-sets, we found the lowest classification accuracy is 61.24% on SRBCT dataset and highest accuracy is 99.32% on Diffuse large B-cell lymphoma (DLBCL). In UCI datasets, the lowest classification accuracy is 40.04% on the Lymphography using k-nearest neighbor (k-NN) and highest classification accuracy is 99.05% on the ionosphere using support vector machine (SVM).

Predicting the role of protein is one of the most challenging problems. There are few approaches available for the prediction of role of unknown protein in terms of drug target or vaccine candidate. We propose here Naïve Bayes probabilistic classifier, a promising method for reliable predictions. This method is tested on the proteins identified in our mass spectrometry based membrane protemics study of Leishmania donovani parasite that causes a fatal disease (Visceral Leishmaniasis) in humans all around the world. Most of the vaccine/drug targets belonging to membrane proteins are represented as key players in the pathogenesis of Leishmania infection. Analyses of our previous results, using Naïve Bayes probabilistic classifier, indicate that this method predicts the role of unknown/hypothetical protein (as drug target/vaccine candidate) significantly with higher precision. We have employed this method in order to provide probabilistic predictions of unknown/hypothetical proteins as targets. This study reports the unknown/hypothetical proteins of Leishmania membrane fraction as a potential drug targets and vaccine candidate which is vital information for this parasite. Future molecular studies and characterization of these potent targets may produce a recombinant therapeutic/prophylactic tool against Visceral Leishmaniasis. These unknown/hypothetical proteins may open a vast research field to be exploited for novel treatment strategies.

Knowing faulty modules prior to testing makes testing more effective and helps to obtain reliable software. Here, we develop a framework for automatic extraction of human understandable fuzzy rules for software fault detection/classification. This is an integrated framework to simultaneously identify useful determinants (attributes) of faults and fuzzy rules using those attributes. At the beginning of the training, the system assumes every attribute (feature) as a useless feature and then uses a concept of feature attenuating gate to select useful features. The learning process opens the gates or closes them more tightly based on utility of the features. Our system can discard derogatory and indifferent attributes and select the useful ones. It can also exploit subtle nonlinear interaction between attributes. In order to demonstrate the effectiveness of the framework, we have used several publicly available software fault data sets and compared the performance of our method with that of some existing methods. The results using tenfold cross-validation setup show that our system can find useful fuzzy rules for fault prediction.