Recent advances in large language models (LLMs) have enabled promising progress in diagnosis prediction from electronic health records (EHRs). However, existing LLM-based approaches tend to overfit to historically observed diagnoses, often overlooking novel yet clinically important conditions that are critical for early intervention. To address this, we propose EviCare, an in-context reasoning framework that integrates deep model guidance into LLM-based diagnosis prediction. Rather than prompting LLMs directly with raw EHR inputs, EviCare performs (1) deep model inference for candidate selection, (2) evidential prioritization for set-based EHRs, and (3) relational evidence construction for novel diagnosis prediction. These signals are then composed into an adaptive in-context prompt to guide LLM reasoning in an accurate and interpretable manner. Extensive experiments on two real-world EHR benchmarks (MIMIC-III and MIMIC-IV) demonstrate that EviCare achieves significant performance gains, which consistently outperforms both LLM-only and deep model-only baselines by an average of 20.65% across precision and accuracy metrics. The improvements are particularly notable in challenging novel diagnosis prediction, yielding average improvements of 30.97%.

Knowledge graphs (KGs) store enormous facts as relationships between entities. Due to the long-tailed distribution of relations and the incompleteness of KGs, there is growing interest in few-shot knowledge graph completion (FKGC). Existing FKGC methods often assume the existence of all entities in KGs, which may not be practical since new relations and entities can emerge over time. Therefore, we focus on a more challenging task called inductive few-shot knowledge graph completion (I-FKGC), where both relations and entities during the test phase are unknown before. Inspired by the idea of inductive reasoning, we cast I-FKGC as an inductive reasoning problem. Specifically, we propose a novel Graph Stochastic Neural Process ( GS-NP ) approach, which consists of two major modules. In the first module, to obtain a generalized hypothesis (e.g., shared subgraph), we present a neural process-based hypothesis extractor that models the joint distribution of hypothesis, from which we can sample a hypothesis for predictions. In the second module, based on the hypothesis, we propose a graph stochastic attention-based predictor to test if the triple in the query set aligns with the extracted hypothesis. Meanwhile, the predictor can generate an explanatory subgraph identified by the hypothesis. Finally, the training of these two modules is seamlessly combined into a unified objective function, of which the effectiveness is verified by theoretical analyses as well as empirical studies. Extensive experiments on three public datasets demonstrate that our method outperforms existing methods and derives new state-of-the-art performance.

Conversational Recommender Systems (CRSs) aim to provide personalized recommendations by capturing user preferences through interactive dialogues. Explainability in CRSs is crucial as it enables users to understand the reasoning behind recommendations, increasing system transparency and trustworthiness. However, current CRSs often leverage knowledge graphs (KGs) or language models to extract and represent user preferences as latent vectors, which limits their explainability. Large language models (LLMs) offer powerful reasoning capabilities that can bridge this gap by generating human-understandable preference summaries. However, effectively reasoning over user preferences in CRSs remains challenging as LLMs pre-trained on large-scale corpora may not be well-suited for analyzing user preferences, which requires domain-specific knowledge. While KGs provide rich domain knowledge, integrating them with LLMs encounters a significant modality gap between structured KG information and unstructured conversations. In this paper, we propose COMPASS (Compact Preference Analyzer and Summarization System), a plug-and-play framework that synergizes LLMs and KGs to reason over user preferences, enhancing the performance and explainability of existing CRSs. COMPASS employs a two-stage training approach: first, it bridges the gap between the structured KG and natural language through novel graph entity captioning pre-training. This enables the LLM to transform KG entities into natural language descriptions, allowing it to comprehend domain-specific knowledge. Next, COMPASS optimizes user preference reasoning via knowledgeaware instruction fine-tuning, where the LLM learns to reason and summarize user preferences from dialogue histories and KG-augmented context. This enables COMPASS to perform knowledge-aware reasoning and generate interpretable user preferences that can seamlessly integrate with existing CRS models for improving recommendation performance and explainability. Our experiments on benchmark datasets demonstrate the effectiveness of COMPASS in improving various CRS models.

In recent years, the landscape of digital biomedicine and healthcare has been reshaped due to the disruptive breakthroughs in AIfacilitated by tremendous data and high-performance computers, large language models (LLMs) have transformed information technology from accessing data to performing analytical tasks.While demonstrating unprecedented capabilities, LLMs have been found unreliable in tasks requiring factual knowledge and rigorous reasoning.Biomedicine and healthcare, as an important vertical domain rapidly benefitting from progress in AI, necessitates strict requirements on the accuracy, controllability, and interpretability of analytical models, posing critical challenges for LLMs.Despite recent studies addressing the hallucination problem of LLMs, research on empowering LLMs with the ability to plan, reason, and ground with explicit knowledge has also started to prosper, especially in the biomedicine and healthcare domain.On the other hand, biomedical data are enormous and notoriously complex, coming from various sources (e.g., biomedical knowledge bases, online literature, and hospitals) and bearing various modalities (e.g., tables, texts, images and time-series).Healthcare professionals have spent decades collecting, cleaning, and curating various types of data.The processes are extremely costly, producing various datasets with different data schemas, coding systems, and quality standards, many privately

Explainable recommendation has demonstrated significant advantages in informing users about the logic behind recommendations, thereby increasing system transparency, effectiveness, and trustworthiness. To provide personalized and interpretable explanations, existing works often combine the generation capabilities of large language models (LLMs) with collaborative filtering (CF) information. CF information extracted from the user-item interaction graph captures the user behaviors and preferences, which is crucial for providing informative explanations. However, due to the complexity of graph structure, effectively extracting the CF information from graphs still remains a challenge. Moreover, existing methods often struggle with the integration of extracted CF information with LLMs due to its implicit representation and the modality gap between graph structures and natural language explanations. To address these challenges, we propose G-Refer, a framework using Graph Retrieval-augmented large language models (LLMs) for explainable recommendation. Specifically, we first employ a hybrid graph retrieval mechanism to retrieve explicit CF signals from both structural and semantic perspectives. The retrieved CF information is explicitly formulated as human-understandable text by the proposed graph translation and accounts for the explanations generated by LLMs. To bridge the modality gap, we introduce knowledge pruning and retrieval-augmented fine-tuning to enhance the ability of LLMs to process and utilize the retrieved CF information to generate explanations. Extensive experiments show that G-Refer achieves superior performance compared with existing methods in both explainability and stability. Codes and data are available at https://github.com/Yuhan1i/G-Refer.

Community detection has gained significant research interest within the data mining field. It involves identifying subsets of nodes with dense internal connections and sparse external connections. Most studies on community detection focus solely on identifying non-overlapping communities in a static graph. However, in practice, communities often overlap, and the structure of the graphs is dynamically evolving. This dynamic nature leads to community changes and poses a significant challenge in detecting overlapping communities on temporal graphs (T-OCD). While graph neural networks have shown great performance in generating node representations for community detection, learning representations that capture temporal graph structures and support overlapping community detection remain an open question. To address these challenges, we present T-OCDIB , a novel approach for T emporal O verlapping C ommunity D etection guided by I nformation B ottleneck. Specifically, we first propose an overlapping community detection approach for static graphs, under the guidance of a community-oriented information bottleneck. This approach allows us to learn discriminative node representations specific to each community, facilitating the detection of overlapping communities. Following this, we extend this method to temporal graphs by presenting a temporal convolution module. This module uses adaptive weight matrices based on evolving graph structures to capture temporal dependencies for community detection. Additionally, to promote smooth transitions between consecutive communities, we introduce a temporal smoothing module to further constrain changes in community structure. We evaluate the proposed approach on both real-world and synthetic temporal networks. Experimental results illustrate the superiority of T-OCDIB over other community detection methods.

Large language models (LLMs), such as ChatGPT and GPT4, are making new waves in the field of natural language processing and artificial intelligence, due to their emergent ability and generalizability. However, LLMs are black-box models, which often fall short of capturing and accessing factual knowledge. In contrast, Knowledge Graphs (KGs), Wikipedia and Huapu for example, are structured knowledge models that explicitly store rich factual knowledge. KGs can enhance LLMs by providing external knowledge for inference and interpretability. Meanwhile, KGs are difficult to construct and evolve by nature, which challenges the existing methods in KGs to generate new facts and represent unseen knowledge. Therefore, it is complementary to unify LLMs and KGs together and simultaneously leverage their advantages. In this article, we present a forward-looking roadmap for the unification of LLMs and KGs. Our roadmap consists of three general frameworks, namely,1) KG-enhanced LLMs,which incorporate KGs during the pre-training and inference phases of LLMs, or for the purpose of enhancing understanding of the knowledge learned by LLMs;2) LLM-augmented KGs,that leverage LLMs for different KG tasks such as embedding, completion, construction, graph-to-text generation, and question answering; and3) Synergized LLMs + KGs, in which LLMs and KGs play equal roles and work in a mutually beneficial way to enhance both LLMs and KGs for bidirectional reasoning driven by both data and knowledge. We review and summarize existing efforts within these three frameworks in our roadmap and pinpoint their future research directions.

Large-scale e-commercial platforms in the real-world usually contain various recommendation scenarios (domains) to meet demands of diverse customer groups. Multi-Domain Recommendation (MDR), which aims to jointly improve recommendations on all domains and easily scales to thousands of domains, has attracted increasing attention from practitioners and researchers. Existing MDR methods usually employ a shared structure and several specific components to respectively leverage reusable features and domain-specific information. However, data distribution differs across domains, making it challenging to develop a general model that can be applied to all circumstances. Additionally, during training, shared parameters often suffer from domain conflict while specific parameters are inclined to overfitting on data sparsity domains. In this paper, we first present a scalable MDR platform served in Taobao that enables to provide services for thousands of domains without specialists involved. To address the problems of MDR methods, we propose a novel model agnostic learning framework, namely MAMDR, for the multi-domain recommendation. Specifically, we first propose a Domain Negotiation (DN) strategy to alleviate the conflict between domains. Then, we develop a Domain Regularization (DR) to improve the generalizability of specific parameters by learning from other domains. We integrate these components into a unified framework and present MAMDR, which can be applied to any model structure to perform multi-domain recommendation. Finally, we present a large-scale implementation of MAMDR in the Taobao application and construct various public MDR benchmark datasets which can be used for following studies. Extensive experiments on both benchmark datasets and industry datasets demonstrate the effectiveness and generalizability of MAMDR.

Knowledge graphs (KGs), as a structured form of knowledge representation, have been widely applied in the real world. Recently, few-shot knowledge graph completion (FKGC), which aims to predict missing facts for unseen relations with few-shot associated facts, has attracted increasing attention from practitioners and researchers. However, existing FKGC methods are based on metric learning or meta-learning, which often suffer from the out-of-distribution and overfitting problems. Meanwhile, they are incompetent at estimating uncertainties in predictions, which is critically important as model predictions could be very unreliable in few-shot settings. Furthermore, most of them cannot handle complex relations and ignore path information in KGs, which largely limits their performance. In this paper, we propose a normalizing flow-based neural process for few-shot knowledge graph completion (NP-FKGC). Specifically, we unify normalizing flows and neural processes to model a complex distribution of KG completion functions. This offers a novel way to predict facts for few-shot relations while estimating the uncertainty. Then, we propose a stochastic ManifoldE decoder to incorporate the neural process and handle complex relations in few-shot settings. To further improve performance, we introduce an attentive relation path-based graph neural network to capture path information in KGs. Extensive experiments on three public datasets demonstrate that our method significantly outperforms the existing FKGC methods and achieves state-of-the-art performance. Code is available at https://github.com/RManLuo/NP-FKGC.git.

Content Warning: this paper may contain content that is offensive or upsetting.

Link prediction on dynamic graphs is an important task in graph mining. Existing approaches based on dynamic graph neural networks (DGNNs) typically require a significant amount of historical data (interactions over time), which is not always available in practice. The missing links over time, which is a common phenomenon in graph data, further aggravates the issue and thus creates extremely sparse and dynamic graphs. To address this problem, we propose a novel method based on the neural process, called Graph Sequential Neural ODE Process (GSNOP). Specifically, GSNOP combines the advantage of the neural process and neural ordinary differential equation that models the link prediction on dynamic graphs as a dynamic-changing stochastic process. By defining a distribution over functions, GSNOP introduces the uncertainty into the predictions, making it generalize to more situations instead of overfitting to the sparse data. GSNOP is also agnostic to model structures that can be integrated with any DGNN to consider the chronological and geometrical information for link prediction. Extensive experiments on three dynamic graph datasets show that GSNOP can significantly improve the performance of existing DGNNs and outperform other neural process variants.

Heterogeneous graphs, which contain nodes and edges of multiple types, are prevalent in various domains, including bibliographic networks, social media, and knowledge graphs. As a fundamental task in analyzing heterogeneous graphs, relevance measure aims to calculate the relevance between two objects of different types, which has been used in many applications such as web search, recommendation, and community detection. Most of existing relevance measures focus on homogeneous networks where objects are of the same type, and a few measures are developed for heterogeneous graphs, but they often need the pre-defined meta-path. Defining meaningful meta-paths requires much domain knowledge, which largely limits their applications, especially on schema-rich heterogeneous graphs like knowledge graphs. Recently, the Graph Neural Network (GNN) has been widely applied in many graph mining tasks, but it has not been applied for measuring relevance yet. To address the aforementioned problems, we propose a novel GNN-based relevance measure, namely GSim. Specifically, we first theoretically analyze and show that GNN is effective for measuring the relevance of nodes in the graph. We then propose a context path-based graph neural network (CP-GNN) to automatically leverage the semantics in heterogeneous graphs. Moreover, we exploit CP-GNN to support relevance measures between two objects of any type. Extensive experiments demonstrate that GSim outperforms existing measures. (Coda and data is available at this linkhttps://github.com/RManLuo/GSim).

Session-based recommendation has recently attracted more and more research efforts. Most existing approaches are intuitively proposed to discover users' potential preferences or interests from the anonymous session data. This apparently ignores the fact that these sequential behavior data usually reflect session user's potential demand, i.e., a semantic level factor, and therefore how to estimate underlying demands from a session has become a challenging task. To tackle the aforementioned issue, this paper proposes a novel demand-aware graph neural network model. Particularly, a demand modeling component is designed to extract the underlying multiple demands of each session. Then, the demand-aware graph neural network is designed to first construct session demand graphs and then learn the demand-aware item embeddings to make the recommendation. The mutual information loss is further designed to enhance the quality of the learnt embeddings. Extensive experiments have been performed on two real-world datasets and the proposed model achieves the SOTA model performance.

Community detection, aiming to group the graph nodes into clusters with dense inner-connection, is a fundamental graph mining task. Recently, it has been studied on the heterogeneous graph, which contains multiple types of nodes and edges, posing great challenges for modeling the high-order relationship between nodes. With the surge of graph embedding mechanism, it has also been adopted to community detection. A remarkable group of works use the meta-path to capture the high-order relationship between nodes and embed them into nodes' embedding to facilitate community detection. However, defining meaningful meta-paths requires much domain knowledge, which largely limits their applications, especially on schema-rich heterogeneous graphs like knowledge graphs. To alleviate this issue, in this paper, we propose to exploit the context path to capture the high-order relationship between nodes, and build a Context Path-based Graph Neural Network (CP-GNN) model. It recursively embeds the high-order relationship between nodes into the node embedding with attention mechanisms to discriminate the importance of different relationships. By maximizing the expectation of the co-occurrence of nodes connected by context paths, the model can learn the nodes' embeddings that both well preserve the high-order relationship between nodes and are helpful for community detection. Extensive experimental results on four real-world datasets show that CP-GNN outperforms the state-of-the-art community detection methods1.