Urban scene reconstruction is crucial for real-world autonomous driving simulators. Although existing methods have achieved photorealistic reconstruction, they mostly focus on pinhole cameras and neglect fisheye cameras. In fact, how to effectively simulate fisheye cameras in driving scene remains an unsolved problem. In this work, we propose UniGaussian, a novel approach that learns a unified 3D Gaussian representation from multiple camera models for urban scene reconstruction in autonomous driving. Our contributions are two-fold. First, we propose a new differentiable rendering method that distorts 3D Gaussians using a series of affine transformations tailored to fisheye camera models. This addresses the compatibility issue of 3D Gaussian splatting with fisheye cameras, which is hindered by light ray distortion caused by lenses or mirrors. Besides, our method maintains real-time rendering while ensuring differentiability. Second, built on the differentiable rendering method, we design a new framework that learns a unified Gaussian representation from multiple camera models. By applying affine transformations to adapt different camera models and regularizing the shared Gaussians with supervision from different modalities, our framework learns a unified 3D Gaussian representation with input data from multiple sources and achieves holistic driving scene understanding. As a result, our approach models multiple sensors (pinhole and fisheye cameras) and modalities (depth, semantic, normal and LiDAR point clouds). Our experiments show that our method achieves superior rendering quality and fast rendering speed for driving scene simulation.

BACKGROUND: Multi-drug combinations represent an effective strategy for treating complex diseases. However, due to the vast number of unknown interactions among drugs, accurately predicting drug-drug interactions (DDIs) is essential for preventing adverse drug reactions that may cause serious harm to patients. Therefore, DDI prediction plays a critical role in pharmacology. RESULTS: In this paper, we propose a novel DDI prediction model that integrates a self-attention mechanism with a capsule neural network, termed ACaps-DDI. The model effectively combines chemical information from internal drug substructures with biological information from external drug targets and drug-metabolizing enzymes to predict potential drug-drug interactions. CONCLUSIONS: Experimental results on two benchmark datasets show that the ACaps-DDI model outperforms six other classification models across seven evaluation metrics, demonstrating its strong predictive performance and generalization ability. Ablation studies further confirm the effectiveness of individual components within the ACaps-DDI architecture. Finally, case studies involving three drugs (cannabidiol, torasemide, and cyclophosphamide) validate the model's ability to predict previously unknown drug interactions. In conclusion, the ACaps-DDI model exhibits high predictive accuracy for known drugs and demonstrates promising predictive capability for unseen drugs, highlighting its practical significance for clinical research on drug interactions.

We address the challenge of domain adaptation in LiDAR-based 3D object detection by introducing a simple yet effective training strategy known as Gradual Batch Alternation. This method enables adaptation from a well-labeled source domain to an insufficiently labeled target domain. Initially, training commences with alternating batches of samples from both the source and target domains. As the training progresses, we gradually reduce the number of samples from the source domain. Consequently, the model undergoes a gradual transition towards the target domain, resulting in improved adaptation. Domain adaptation experiments for 3D object detection on four benchmark autonomous driving datasets, namely ONCE, PandaSet, Waymo, and nuScenes, demonstrate significant performance gains over prior works and strong baselines.

Contemporary LiDAR-based 3D object detection methods mostly focus on single-domain learning or cross-domain adaptive learning. However, for autonomous driving systems, optimizing a specific LiDAR-based 3D object detector for each domain is costly and lacks of scalability in real-world deployment. It is desirable to train a universal LiDAR-based 3D object detector from multiple domains. In this work, we propose the first attempt to explore multi-domain learning and generalization for LiDAR-based 3D object detection. We show that jointly optimizing a 3D object detector from multiple domains achieves better generalization capability compared to the conventional single-domain learning model. To explore informative knowledge across domains towards a universal 3D object detector, we propose a multi-domain knowledge transfer framework with universal feature transformation. This approach leverages spatial-wise and channel-wise knowledge across domains to learn universal feature representations, so it facilitates to optimize a universal 3D object detector for deployment at different domains. Extensive experiments on four benchmark datasets (Waymo, KITTI, NuScenes and ONCE) show the superiority of our approach over the state-of-the-art approaches for multi-domain learning and generalization in LiDAR-based 3D object detection.

In this paper we address the challenging problem of domain adaptation in LiDAR semantic segmentation. We consider the setting where we have a fully-labeled data set from source domain and a target domain with a few labeled and many unlabeled examples. We propose a domain adaptation framework that mitigates the issue of domain shift and produces appealing performance on the target domain. To this end, we develop a GAN-based image-to-image translation engine that has generators with alternating connections, and couple it with a LiDAR semantic segmentation network. Our framework is hybrid in nature in the sense that our model learning is composed of self-supervision, semi-supervision and unsupervised learning. Extensive experiments on benchmark LiDAR semantic segmentation data sets demonstrate that our method achieves superior performance in comparison to state-of-the-art baselines and prior arts.

In this article, a new dataset, the driver emotion facial expression (DEFE) dataset for drivers’ spontaneous emotions analysis is introduced. The dataset includes facial expression recordings from 60 participants during driving. After watching a selected video-audio clip to elicit a specific emotion, each participant completed the driving tasks in the same driving scenario and rated his/her emotional responses during the driving processes from the aspects of dimensional emotion method and discrete emotion method. The study also conducted classification experiments to recognize the scales of arousal, valence, dominance, as well as the emotion category and intensity to establish baseline results for the proposed dataset. Furthermore, this paper compared emotion recognition results difference through facial expressions between dynamic driving and static life scenarios. The results showed that dynamic driving and static life datasets were different in emotion recognition results. To further explore the reasons for the difference in emotion recognition results, the analysis from the AU (action unit) presence perspective was studied. The results showed significant differences in the AUs presence of facial expressions between dynamic driving and static life scenarios, indicating that drivers’ facial expressions may be affected by the driving task to influence the recognition of drivers’ emotions through facial expressions. Therefore, to accurately recognize the drivers’ emotions to establish a reliable emotion-aware human-machine interaction system, thereby improving driving safety and comfort, publishing a human emotion dataset specifically for the driver is necessary. The proposed dataset will be publicly available so that researchers worldwide can use it to develop and examine their driver emotion analysis methods. To the best of our knowledge, this is currently the only public driver facial expression dataset.