Deformable image registration (DIR), aiming to find spatial correspondence between images, is one of the most critical problems in the domain of medical image analysis. In this paper, we present a novel, generic, and accurate diffeomorphic image registration framework that utilizes neural ordinary differential equations (NODEs). We model each voxel as a moving particle and consider the set of all voxels in a 3D image as a high-dimensional dynamical system whose trajectory determines the targeted deformation field. Our method leverages deep neural networks for their expressive power in modeling dynamical systems, and simultaneously optimizes for a dynamical system between the image pairs and the corresponding transformation. Our formulation allows various constraints to be imposed along the transformation to maintain desired regularities. Our experiment results show that our method outperforms the benchmarks under various metrics. Additionally, we demonstrate the feasibility to expand our framework to register multiple image sets using a unified form of transformation, which could possibly serve a wider range of applications.

Understanding decentralized dynamics from collective behaviors in swarms is crucial for informing robot controller designs in artificial swarms and multi-agent robotic systems. However, the complexity in agent-to-agent interactions and the decentralized nature of most swarms pose a significant challenge to the extraction of single-robot control laws from collective behaviors. In this work, we consider the important task of learning decentralized single-robot controllers based solely on the state observations of a swarm's trajectory. We present a general framework by adopting knowledge-based neural ordinary differential equations (KNODE) ─ a hybrid machine learning method capable of combining artificial neural networks with known agent dynamics. Our approach distinguishes itself from most prior works in that we do not require action data for learning. We apply our framework to two different flocking swarms in 2D and 3D respectively, and demonstrate efficient training by leveraging the graphical structure of the swarms' information network. We further show that the learnt single-robot controllers can not only mimic flocking behavior in the original swarm but also scale to swarms with more robots.