Aphasia, affecting one-third of stroke survivors, impairs language comprehension and speech production, leading to challenges in daily interactions, social isolation, and economic losses. Assessing aphasia is crucial for effective rehabilitation and recovery in patients. However, the conventional behavioral-based evaluation, reliant on speech pathologists, is susceptible to individual variability, resulting in high labor costs, time-consuming processes, and low robustness. To address these limitations, this study introduces a novel evaluation method based on medical image processing and artificial intelligence. Magnetic resonance imaging (MRI) provides exceptional spatial resolution while mitigating the impact of individual variability. The image processing techniques were employed to extract pathological features, specifically region-of-interest (ROI)-based features. Subsequently, the evaluation models were trained using ROI-based features which initially identify the occurrence of aphasia and then categorize the type of aphasia, aiding clinicians in tailoring treatment to various therapeutic approaches and intensities. The evaluation models also predict the severity and generate scores for four types of language function: spontaneous speech, auditory comprehension, naming, and repetition. Both aphasia occurrence detection and aphasia type classification attain impressive accuracy rates of 100.00 $\pm$ 0.00% and 85.00 $\pm$ 13.23%, respectively. The severity prediction yields the lowest root mean square error (RMSE) of 17.03 $\pm$ 2.75, while the assessment of four language functions achieves the best RMSE of 1.27 $\pm$ 0.82. Utilising the advantages of a medical imaging-based automation approach, the proposed aphasia evaluation method provides a comprehensive procedure and generates rather accurate results. Hence it could assist the aphasia rehabilitation and substantially reduce clinicians' workload.

Breast cancer is the most common malignant tumor among women and the second cause of cancer-related death. Early diagnosis in clinical practice is crucial for timely treatment and prognosis. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has revealed great usability in the preoperative diagnosis and assessing therapy effects thanks to its capability to reflect the morphology and dynamic characteristics of breast lesions. However, most existing computer-assisted diagnosis algorithms only consider conventional radiomic features when classifying benign and malignant lesions in DCE-MRI. In this study, we propose to fully leverage the dynamic characteristics from the kinetic curves as well as the radiomic features to boost the classification accuracy of benign and malignant breast lesions. The proposed method is a fully automated solution by directly analyzing the 3D features from the DCE-MRI. The proposed method is evaluated on an in-house dataset including 200 DCE-MRI scans with 298 breast tumors (172 benign and 126 malignant tumors), achieving favorable classification accuracy with an area under curve (AUC) of 0.94. By simultaneously considering the dynamic and radiomic features, it is beneficial to effectively distinguish between benign and malignant breast lesions. The algorithm is publicly available at https://github.com/ryandok/JPA.