Batteryless energy-harvesting sensor nodes can operate indefinitely, but if the harvesting rate is too low, they must operate intermittently. Intermittent operation imposes various challenges upon the system. One of the least-studied is communication–if nodes are unpowered for long, unpredictable periods of time, how can they reliably communicate with each other? In prior work, we proposed the concept of lifecycle management protocols (LMPs) to mitigate this issue and enable wireless communication directly between intermittent sensor nodes using active radios. In this paper, we propose a design framework for a class of LMPs. We then provide analytical models for the delay and throughput of two-node communication using this framework. Finally, we implement this framework on hardware and validate our models in an experimental setting. To the best of our knowledge, this is the first design framework for, and implementation of, protocols for enabling and improving general-purpose communication between intermittent sensor nodes using active radios.