Stereo matching recovers depth from image correspondences. Existing methods struggle to handle ill-posed regions with limited matching cues, such as occlusions and textureless areas. To address this, we propose MonSter, a novel method that leverages the complementary strengths of monocular depth estimation and stereo matching. MonSter integrates monocular depth and stereo matching into a dual-branch architecture to iteratively improve each other. Confidence-based guidance adaptively selects reliable stereo cues for monodepth scale-shift recovery. The refined monodepth is in turn guides stereo effectively at ill-posed regions. Such iterative mutual enhancement enables MonSter to evolve monodepth priors from coarse object-level structures to pixel-level geometry, fully unlocking the potential of stereo matching. As shown in Fig. 2, MonSter ranks 1stacross five most commonly used leaderboards — SceneFlow, KITTI 2012, KITTI 2015, Middlebury, and ETH3D. Achieving up to 49.5% improvements (Bad 1.0 on ETH3D) over the previous best method. Comprehensive analysis verifies the effectiveness of MonSter in ill-posed regions. In terms of zero-shot generalization, MonSter significantly and consistently outperforms state-of-the-art across the board. The code is publicly available at: https://github.com/Junda24/MonSter.

The realistic reconstruction of street scenes is critical for developing real-world simulators in autonomous driving. Most existing methods rely on object pose annotations, using these poses to reconstruct dynamic objects and move them during the rendering process. This dependence on high-precision object annotations limits large-scale and extensive scene reconstruction. To address this challenge, we propose Bézier curve Gaussian splatting (BézierGS), which represents the motion trajectories of dynamic objects using learnable Bézier curves. This approach fully leverages the temporal information of dynamic objects and, through learnable curve modeling, automatically corrects pose errors. By introducing additional supervision on dynamic object rendering and inter-curve consistency constraints, we achieve reasonable and accurate separation and reconstruction of scene elements. Extensive experiments on the Waymo Open Dataset and the nuPlan benchmark demonstrate that BézierGS outperforms state-of-the-art alternatives in both dynamic and static scene components reconstruction and novel view synthesis.

State-of-the-art stereo matching methods typically use costly 3D convolutions to aggregate a full cost volume, but their computational demands make mobile deployment challenging. Directly applying 2D convolutions for cost aggregation often results in edge blurring, detail loss, and mismatches in textureless regions. Some complex operations, like deformable convolutions and iterative warping, can partially alleviate this issue; however, they are not mobile-friendly, limiting their deployment on mobile devices. In this paper, we present a novel bilateral aggregation network (BANet) for mobile stereo matching that produces high-quality results with sharp edges and fine details using only 2D convolutions. Specifically, we first separate the full cost volume into detailed and smooth volumes using a spatial attention map, then perform detailed and smooth aggregations accordingly, ultimately fusing both to obtain the final disparity map. Experimental results demonstrate that our BANet-2D significantly outperforms other mobile-friendly methods, achieving 35.3\% higher accuracy on the KITTI 2015 leaderboard than MobileStereoNet-2D, with faster runtime on mobile devices. Code: \textcolor{magenta}{https://github.com/gangweix/BANet}.

LiDAR novel view synthesis (NVS) has emerged as a novel task within LiDAR simulation, offering valuable simulated point cloud data from novel viewpoints to aid in autonomous driving systems. However, existing LiDAR NVS methods typically rely on neural radiance fields (NeRF) as their 3D representation, which incurs significant computational costs in both training and rendering. Moreover, NeRF and its variants are designed for symmetrical scenes, making them ill-suited for driving scenarios. To address these challenges, we propose GS-LiDAR, a novel framework for generating realistic LiDAR point clouds with panoramic Gaussian splatting. Our approach employs 2D Gaussian primitives with periodic vibration properties, allowing for precise geometric reconstruction of both static and dynamic elements in driving scenarios. We further introduce a novel panoramic rendering technique with explicit ray-splat intersection, guided by panoramic LiDAR supervision. By incorporating intensity and ray-drop spherical harmonic (SH) coefficients into the Gaussian primitives, we enhance the realism of the rendered point clouds. Extensive experiments on KITTI-360 and nuScenes demonstrate the superiority of our method in terms of quantitative metrics, visual quality, as well as training and rendering efficiency.

Recent advances in LVLMs have improved vision-language understanding, but they still struggle with spatial perception, limiting their ability to reason about complex 3D scenes. Unlike previous approaches that incorporate 3D representations into models to improve spatial understanding, we aim to unlock the potential of VLMs by leveraging spatially relevant image data. To this end, we introduce a novel 2D spatial data generation and annotation pipeline built upon scene data with 3D ground-truth. This pipeline enables the creation of a diverse set of spatial tasks, ranging from basic perception tasks to more complex reasoning tasks. Leveraging this pipeline, we construct SPAR-7M, a large-scale dataset generated from thousands of scenes across multiple public datasets. In addition, we introduce SPAR-Bench, a benchmark designed to offer a more comprehensive evaluation of spatial capabilities compared to existing spatial benchmarks, supporting both single-view and multi-view inputs. Training on both SPAR-7M and large-scale 2D datasets enables our models to achieve state-of-the-art performance on 2D spatial benchmarks. Further fine-tuning on 3D task-specific datasets yields competitive results, underscoring the effectiveness of our dataset in enhancing spatial reasoning.

Leveraging diverse robotic data for pretraining remains a critical challenge. Existing methods typically model the dataset’s action distribution using simple observations as inputs. However, these inputs are often incomplete, resulting in a dispersed conditional action distribution—an issue we refer to as coordinate system chaos and state chaos. This inconsistency significantly hampers pretraining efficiency. To address this, we propose 4D-VLA, a novel approach that effectively integrates 4D information into the input to mitigate these sources of chaos. Our model introduces depth and temporal information into visual features with sequential RGB-D inputs, aligning the coordinate systems of the robot and the scene. This alignment endows the model with strong spatiotemporal reasoning capabilities while minimizing training overhead. Additionally, we introduce Memory bank sampling, a frame sampling strategy designed to extract informative frames from historical images, further improving effectiveness and efficiency. Experimental results demonstrate that our pretraining method and architectural components substantially enhance model performance. In both simulated and real-world experiments, our model achieves a significant increase in success rate over OpenVLA.To further assess spatial perception and generalization to novel views, we introduce MV-Bench, a multi-view simulation benchmark. Our model consistently outperforms existing methods, demonstrating stronger spatial understanding and adaptability.

Autonomous driving simulation system plays a crucial role in enhancing self-driving data and simulating complex and rare traffic scenarios, ensuring navigation safety. However, traditional simulation systems, which often heavily rely on manual modeling and 2D image editing, struggled with scaling to extensive scenes and generating realistic simulation data. In this study, we present S-NeRF++, an innovative autonomous driving simulation system based on neural reconstruction. Trained on widely-used self-driving datasets, such as nuScenes and Waymo, S-NeRF++ can generate a large number of realistic street scenes and foreground objects with high rendering quality as well as offering considerable flexibility in manipulation and simulation. Specifically, S-NeRF++ is an enhanced neural radiance field for synthesizing large-scale scenes and moving vehicles, with improved scene parameterization and camera pose learning. The system effectively utilizes noisy and sparse LiDAR data to refine training and address depth outliers, ensuring high-quality reconstruction and novel-view rendering. It also provides a diverse foreground asset bank by reconstructing and generating different foreground vehicles to support comprehensive scenario creation. Moreover, we have developed an advanced foreground-background fusion pipeline that skillfully integrates illumination and shadow effects, further enhancing the realism of our simulations. With the high-quality simulated data provided by our S-NeRF++, we found the perception methods enjoy performance boosts on several autonomous driving downstream tasks, further demonstrating our proposed simulator's effectiveness.

MOTIVATION: Personalized cancer treatments require accurate drug response predictions. Existing deep learning methods show promise but higher accuracy is needed to serve the purpose of precision medicine. The prediction accuracy can be improved with not only topology but geometrical information of drugs. RESULTS: A novel deep learning methodology for drug response prediction is presented, named Hi-GeoMVP. It synthesizes hierarchical drug representation with multi-omics data, leveraging graph neural networks and variational autoencoders for detailed drug and cell line representations. Multi-task learning is employed to make better prediction, while both 2D and 3D molecular representations capture comprehensive drug information. Testing on the GDSC dataset confirms Hi-GeoMVP's enhanced performance, surpassing prior state-of-the-art methods by improving the Pearson correlation coefficient from 0.934 to 0.941 and decreasing the root mean square error from 0.969 to 0.931. In the case of blind test, Hi-GeoMVP demonstrated robustness, outperforming the best previous models with a superior Pearson correlation coefficient in the drug-blind test. These results underscore Hi-GeoMVP's capabilities in drug response prediction, implying its potential for precision medicine. AVAILABILITY AND IMPLEMENTATION: The source code is available at https://github.com/matcyr/Hi-GeoMVP.

The drug response prediction problem arises from personalized medicine and drug discovery. Deep neural networks have been applied to the multi-omics data being available for over 1000 cancer cell lines and tissues for better drug response prediction. We summarize and examine state-of-the-art deep learning methods that have been published recently. Although significant progresses have been made in deep learning approach in drug response prediction, deep learning methods show their weakness for predicting the response of a drug that does not appear in the training dataset. In particular, all the five evaluated deep learning methods performed worst than the similarity-regularized matrix factorization (SRMF) method in our drug blind test. We outline the challenges in applying deep learning approach to drug response prediction and suggest unique opportunities for deep learning integrated with established bioinformatics analyses to overcome some of these challenges.