Chronic diseases have become the leading cause of death worldwide, a challenge intensified by strained medical resources and an aging population. Individually, patients often struggle to interpret early signs of deterioration or maintain adherence to care plans. In this paper, we introduce VitalDiagnosis, an LLM-driven ecosystem designed to shift chronic disease management from passive monitoring to proactive, interactive engagement. By integrating continuous data from wearable devices with the reasoning capabilities of LLMs, the system addresses both acute health anomalies and routine adherence. It analyzes triggers through context-aware inquiries, produces provisional insights within a collaborative patient–clinician workflow, and offers personalized guidance. This approach aims to promote a more proactive and cooperative care paradigm, with the potential to enhance patient self-management and reduce avoidable clinical workload.

Parameter-efficient fine-tuning (PEFT) methods optimize large language models (LLMs) by modifying or introducing a small number of parameters to enhance alignment with downstream tasks. However, they can result in catastrophic forgetting, where LLMs prioritize new knowledge at the expense of comprehensive world knowledge. A promising approach to mitigate this issue is to recall prior memories based on the original knowledge. To this end, we propose a model-agnostic PEFT framework, IMSM, which Interweaves Memories of a Siamese Large Language Model. Specifically, our siamese LLM is equipped with an existing PEFT method. Given an incoming query, it generates two distinct memories based on the pre-trained and fine-tuned parameters. IMSM then incorporates an interweaving mechanism that regulates the contributions of both original and enhanced memories when generating the next token. This framework is theoretically applicable to all open-source LLMs and existing PEFT methods. We conduct extensive experiments across various benchmark datasets, evaluating the performance of popular open-source LLMs using the proposed IMSM, in comparison to both classical and leading PEFT methods. Our findings indicate that IMSM maintains comparable time and space efficiency to backbone PEFT methods while significantly improving performance and effectively mitigating catastrophic forgetting.

The scientific impact of academic papers is influenced by intricate factors such as dynamic popularity and inherent contribution. Existing models typically rely on static graphs for citation count estimation, failing to differentiate among its sources. In contrast, we propose distinguishing effects derived from various factors and predicting citation increments as estimated potential impacts within the dynamic context. In this research, we introduce a novel model, DPPDCC, which Disentangles the Potential impacts of Papers into Diffusion, Conformity, and Contribution values. It encodes temporal and structural features within dynamic heterogeneous graphs derived from the citation networks and applies various auxiliary tasks for disentanglement. By emphasizing comparative and co-cited/citing information and aggregating snapshots evolutionarily, DPPDCC captures knowledge flow within the citation network. Afterwards, popularity is outlined by contrasting augmented graphs to extract the essence of citation diffusion and predicting citation accumulation bins for quantitative conformity modeling. Orthogonal constraints ensure distinct modeling of each perspective, preserving the contribution value. To gauge generalization across publication times and replicate the realistic dynamic context, we partition data based on specific time points and retain all samples without strict filtering. Extensive experiments on three datasets validate DPPDCC's superiority over baselines for papers published previously, freshly, and immediately, with further analyses confirming its robustness. Our codes and supplementary materials can be found at GitHub (https://github.com/ECNU-Text-Computing/DPPDCC).