We provide design guidelines for the integration of quantum key distribution (QKD) into legacy passive optical networks (PONs). Our study addresses the challenge of quantum coexistence with various PON standards in different network topologies. We develop a novel theoretical model to assess the impact of the passive optical distribution network on both the quantum signal and the generation of scattered Raman photons from classical signals. This work also includes an extensive Raman efficiency experimental evaluation over a wide frequency range. The study evaluates the integration of upstream QKD systems in 32- or 64-user PON scenarios, determining quantum-available bandwidths and maximum supported PON lengths. In single-fibre architectures the coexistence with standards having upstream and downstream classical channels in different telecommunication fibre windows (e.g. XG-PON) is extremely challenging due to the pervasive spectrum placement of the spontaneous Raman scattering noise. However dual-feeder architectures (i.e., placing the QKD receiver at the OLT-side of the protection feeder fibre) can significantly enhance QKD performance and support the key-exchange over the entire standardized PON length for most PON standards and even in case of two-PON standard presence. Finally, the dual-fibre topology allows the quantum coexistence in access networks where three classical standards share the same infrastructure.