Malicious Deepfakes pose serious security risks by producing highly realistic forged faces. While numerous countermeasures have been developed to train binary Deepfake classifiers, their limited generalization capacity restricts practical deployment. To proactively defend against Deepfakes, we propose SVS-WM, a Self-Verifiable Semantic Watermarking strategy. The core idea behind SVS-WM is to embed pairs of correlated watermarks within facial semantics, leveraging the inherent fragility of these features, i.e., any semantic modification will disrupt the watermark correlation, thereby enabling robust Deepfake detection. SVS-WM employs a facial semantic disentanglement and reconstruction network, allowing semi-fragile watermarks to be embedded concurrently across multiple semantic levels, including identity and multi-levels of attributes. Specifically, pairs of pseudo-random noise watermarks are adaptively injected into facial attribute and identity features. During propagation stage, the protected image may encounter identity or facial attributes manipulations, we then detect Deepfakes by verifying the correlation result between the decoded attribute watermark and the extracted identity vector. This unique cross-verification mechanism enables authentication without requiring original reference watermark, thereby realizing blind Deepfake detection. Extensive experiments validate the effectiveness of our approach, achieving an average detection accuracy of 98.19% across diverse Deepfake manipulations.

The challenge of generalization in face forgery detection has become increasingly prominent as manipulation techniques continue to evolve. Although recent image blending-based methods have demonstrated remarkable potential, they often encounter a significant performance drop when applied to datasets exhibiting significant domain gaps. This limitation stems from the exclusive reliance of prior methods on blending unaltered faces with various augmentations to produce common artifacts, which ignores the inherent characteristics of the forged regions. To fully exploit the potential of image blending-based methods for generalizable Deepfake detection, we propose a novel image synthesis framework called Bi-Level Inconsistency Generator (Bi-LIG) to introduce bi-level inconsistency in the synthesized images. Specifically, Bi-LIG generates synthetic images by blending source and target images from both pristine and forged image sets, introducing a) Extrinsic-Inconsistency between real and pseudo-forged regions, and b) Inherent-Inconsistency between real and manipulated areas. In this way, Bi-LIG creates a diverse synthesized image set and establishes a generalizable training domain. Furthermore, we propose a novel face forgery detection network named Token Consistency Constrained Vision Transformer, in which two modules are developed based on patch consistency learning. Firstly, a Patch Token Contrast module is employed to learn the bi-level patch inconsistencies. Secondly, a Progressive Patch Token Assemble module is adopted to aggregate local patch relations and enhance the inconsistency representations. Experimental results demonstrate the effectiveness and superiority of our method on both in-dataset and cross-dataset evaluations. Notably, our approach outperforms state-of-the-art methods by 5.09% and 10.15% on cross-dataset evaluations in DFDCp and DFDC, respectively.

Improving logistics efficiency is a challenging task in logistic systems, since planning the vehicle routes highly relies on the changing traffic conditions and diverse demand scenarios. However, most existing approaches either neglect the dynamic traffic environment or adopt manually designed rules, which fails to efficiently find a high-quality routing strategy. In this paper, we present a novel artificial intelligence (AI) based framework for logistic systems. This framework can simulate the spatio-temporal traffic conditions to form a dynamic environment in a data-driven manner. Under such a simulated environment, it adopts deep reinforcement learning techniques to intelligently generate the optimized routing strategy. Meanwhile, we also design an interactive frontend to visualize the simulated environment and routing strategies, which help operators evaluate the task performance. We will showcase the results of AI-based simulation and optimization in our demonstration.

Targeted protein degradation techniques, such as PROteolysis TArgeting Chimeras (PROTACs), have emerged as powerful tools for selectively removing disease-causing proteins. One challenging problem in this field is designing a linker to connect different molecular fragments to form a stable drug-candidate molecule. Existing models for linker design assume that the relative positions of the fragments are known, which may not be the case in real scenarios. In this work, we address a more general problem where the poses of the fragments are *unknown* in 3D space. We develop a 3D equivariant diffusion model that jointly learns the generative process of both fragment poses and the 3D structure of the linker. By viewing fragments as rigid bodies, we design a fragment pose prediction module inspired by the Newton-Euler equations in rigid body mechanics. Empirical studies on ZINC and PROTAC-DB datasets demonstrate that our model can generate chemically valid, synthetically-accessible, and low-energy molecules under both unconstrained and constrained generation settings.