Self-supervised monocular depth estimation methods severely compromise accuracy in dynamic objects due to their static scene assumption. Existing approaches for dynamic scenes suffer from two critical shortcomings: 1) reliance on supervised segmentation models (requiring costly annotations) or computationally intensive multi-branch models to isolate moving objects, and 2) simple integration of 2D/3D motion flow without reliable supervision for dynamic objects. We propose AdaDepth, a two‑stage framework that jointly performs unsupervised scene decomposition and dynamic-aware depth learning. In the initial structural stage, our geometry-motion joint scene decomposition (GMoDecomp) module ensures the robust generation of a depth prior and simultaneously partitions the scene into multiple regions through the fusion of geometric and motion cues. In the region-adaptive refinement stage, we exploit the depth prior and decomposed regions to introduce motion-aware and geometry-consistent constraints, effectively improving depth estimation in dynamic scenes. AdaDepth achieves accurate depth prediction in highly dynamic scenes without relying on external labels or specialized segmentation models. Extensive experiments on KITTI, Cityscapes, and Waymo Open demonstrate its superiority over state-of-the-art approaches.

Multi-modal methods based on camera and LiDAR sensors have garnered significant attention in the field of 3D detection. However, many prevalent works focus on single or partial stage fusion, leading to insufficient feature extraction and suboptimal performance. In this paper, we introduce a multi-stage cross-modal fusion 3D detection framework, termed CMF-IOU, to effectively address the challenge of aligning 3D spatial and 2D semantic information. Specifically, we first project the pixel information into 3D space via a depth completion network to get the pseudo points, which unifies the representation of the LiDAR and camera information. Then, a bilateral cross-view enhancement 3D backbone is designed to encode LiDAR points and pseudo points. The first sparse-to-distant (S2D) branch utilizes an encoder-decoder structure to reinforce the representation of sparse LiDAR points. The second residual view consistency (ResVC) branch is proposed to mitigate the influence of inaccurate pseudo points via both the 3D and 2D convolution processes. Subsequently, we introduce an iterative voxel-point aware fine grained pooling module, which captures the spatial information from LiDAR points and textural information from pseudo points in the proposal refinement stage. To achieve more precise refinement during iteration, an intersection over union (IoU) joint prediction branch integrated with a novel proposals generation technique is designed to preserve the bounding boxes with both high IoU and classification scores. Extensive experiments show the superior performance of our method on the KITTI, nuScenes and Waymo datasets. The code is available at https://github.com/pami-zwning/CMF-IOU.

Recent studies have demonstrated the significant role that circRNA plays in the progression of human diseases. Identifying circRNA-disease associations (CDA) in an efficient manner can offer crucial insights into disease diagnosis. While traditional biological experiments can be time-consuming and labor-intensive, computational methods have emerged as a viable alternative in recent years. However, these methods are often limited by data sparsity and their inability to explore high-order information. In this paper, we introduce a novel method named Knowledge Graph Encoder from Transformer for predicting CDA (KGETCDA). Specifically, KGETCDA first integrates more than 10 databases to construct a large heterogeneous non-coding RNA dataset, which contains multiple relationships between circRNA, miRNA, lncRNA and disease. Then, a biological knowledge graph is created based on this dataset and Transformer-based knowledge representation learning and attentive propagation layers are applied to obtain high-quality embeddings with accurately captured high-order interaction information. Finally, multilayer perceptron is utilized to predict the matching scores of CDA based on their embeddings. Our empirical results demonstrate that KGETCDA significantly outperforms other state-of-the-art models. To enhance user experience, we have developed an interactive web-based platform named HNRBase that allows users to visualize, download data and make predictions using KGETCDA with ease. The code and datasets are publicly available at https://github.com/jinyangwu/KGETCDA.

Non-coding RNAs (ncRNAs) are a class of RNA molecules that lack the ability to encode proteins in human cells, but play crucial roles in various biological process. Understanding the interactions between different ncRNAs and their impact on diseases can significantly contribute to diagnosis, prevention, and treatment of diseases. However, predicting tertiary interactions between ncRNAs and diseases based on structural information in multiple scales remains a challenging task. To address this challenge, we propose a method called BertNDA, aiming to predict potential relationships between miRNAs, lncRNAs, and diseases. The framework identifies the local information through connectionless subgraph, which aggregate neighbor nodes' feature. And global information is extracted by leveraging Laplace transform of graph structures and WL (Weisfeiler-Lehman) absolute role coding. Additionally, an EMLP (Element-wise MLP) structure is designed to fuse pairwise global information. The transformer-encoder is employed as the backbone of our approach, followed by a prediction-layer to output the final correlation score. Extensive experiments demonstrate that BertNDA outperforms state-of-the-art methods in prediction assignment and exhibits significant potential for various biological applications. Moreover, we develop an online prediction platform that incorporates the prediction model, providing users with an intuitive and interactive experience. Overall, our model offers an efficient, accurate, and comprehensive tool for predicting tertiary associations between ncRNAs and diseases.