Autonomous agents often require accurate methods for detecting and localizing changes in their environment, particularly when observations are captured from unconstrained and inconsistent viewpoints. We propose a novel label-free, pose-agnostic change detection method that integrates information from multiple viewpoints to construct a change-aware 3D Gaussian Splatting (3DGS) representation of the scene. With as few as 5 images of the post-change scene, our approach can learn an additional change channel in a 3DGS and produce change masks that outperform single-view techniques. Our change-aware 3D scene representation additionally enables the generation of accurate change masks for unseen viewpoints. Experimental results demonstrate state-of-the-art performance in complex multi-object scenes, achieving a 1.7× and 1.5× improvement in Mean Intersection Over Union and F1 score respectively over other baselines. We also contribute a new real-world dataset to benchmark change detection in diverse challenging scenes in the presence of lighting variations. Our code and the dataset are available at MV-3DCD.github.io.

Unarguably, deep learning models capable of generalizing to unseen domain data while leveraging a few labels are of great practical significance due to low developmental costs. In search of this endeavor, we study the challenging problem of semi-supervised domain generalization (SSDG), where the goal is to learn a domain-generalizable model while using only a small fraction of labeled data and a relatively large fraction of unlabeled data. Domain generalization (DG) methods show subpar performance under the SSDG setting, whereas semi-supervised learning (SSL) methods demonstrate relatively better performance, however, they are considerably poor compared to the fully-supervised DG methods. Towards handling this new, but challenging problem of SSDG, we propose a novel method that can facilitate the generation of accurate pseudo-labels under various domain shifts. This is accomplished by retaining the domain-level specialism in the classifier during training corresponding to each source domain. Specifically, we first create domain-level information vectors on the fly which are then utilized to learn a domain-aware mask for modulating the classifier's weights. We provide a mathematical interpretation for the effect of this modulation procedure on both pseudo-labeling and model training. Our method is plug-and-play and can be readily applied to different SSL baselines for SSDG. Extensive experiments on six challenging datasets in two different SSDG settings show that our method provides visible gains over the various strong SSL-based SSDG baselines. Our code is available at github.com/DGWM.

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models however require careful training using expert annotations, so that they can be inferred with a degree of known certainty (or uncertainty). To this end, we introduce the concept of uncertainty awareness into a self-supervised contrastive learning model. This is achieved by computing an evidence vector at every epoch, which assesses the model's confidence in its predictions. The derived uncertainty score is then utilized as a metric to selectively label the most crucial images that require further annotation, thus iteratively refining the training process. With just 1-10% of strategically selected annotations, we attain state-of-the-art performance in cancer subtyping on benchmark datasets. Our method not only strategically guides the annotation process to minimize the need for extensive labeled datasets, but also improve the precision and efficiency of classifications. This development is particularly beneficial in settings where the availability of labeled data is limited, offering a promising direction for future research and application in digital pathology. Our code is available at https://github.com/Nirhoshan/AI-for-histopathology

We approach the challenge of addressing semi-supervised domain generalization (SSDG). Specifically, our aim is to obtain a model that learns domain-generalizable features by leveraging a limited subset of labelled data alongside a substantially larger pool of unlabeled data. Existing domain generalization (DG) methods which are unable to exploit unlabeled data perform poorly compared to semi-supervised learning (SSL) methods under SSDG setting. Nevertheless, SSL methods have considerable room for performance improvement when compared to fully- supervised DG training. To tackle this underexplored, yet highly practical problem of SSDG, we make the following core contributions. First, we propose a feature-based conformity technique that matches the posterior distributions from the feature space with the pseudo-label from the model's output space. Second, we develop a semantics alignment loss to learn semantically-compatible representations by regularizing the semantic structure in the feature space. Our method is plug-and-play and can be readily integrated with different SSL-based SSDG baselines without introducing any additional parameters. Extensive experimental results across five challenging DG benchmarks with four strong SSL baselines suggest that our method provides consistent and notable gains in two different SSDG settings. Our code is available at FBC-SA.

Existing GAN-based text-to-image models treat images as 2D pixel arrays. In this paper, we approach the text-to-image task from a different perspective, where a 2D image is represented as an implicit neural representation (INR). We show that straightforward conditioning of the unconditional INR-based GAN method on text inputs is not enough to achieve good performance. We propose a word-level attention-based weight modulation operator that controls the generation process of INR-GAN based on hypernetworks. Our experiments on benchmark datasets show that HyperCGAN achieves competitive performance to existing pixel-based methods and retains the properties of continuous generative models. Project page link: https://kilichbek.github.io/webpagelhypercgan.

Diabetic retinopathy (DR) is caused by long-standing diabetes and is among the fifth leading cause for visual impairment. The prospects of early diagnosis and treatment could be helpful in curing the disease, however, the detection procedure is rather challenging and mostly tedious. Therefore, automated diabetic retinopathy classification using deep learning techniques has gained interest in the medical imaging community. Akin to several other real-world applications of deep learning, the typical assumption of i.i.d data is also violated in DR classification that relies on deep learning. Therefore, developing DR classification methods robust to unseen distributions is of great value. In this paper, we study the problem of generalizing a model to unseen distributions or domains (a.k.a domain generalization) in DR classification. To this end, we propose a simple and effective domain generalization (DG) approach that achieves self-distillation in vision transformers (ViT) via a novel prediction softening mechanism. This prediction softening is an adaptive convex combination of one-hot labels with the model’s own knowledge. We perform extensive experiments on challenging open-source DR classification datasets under both multi-source and more challenging single-source DG settings with three different ViT backbones to establish the efficacy and applicability of our approach against competing methods. For the first time, we report the performance of several state-of-the-art domain generalization (DG) methods on open-source DR classification datasets after conducting thorough experiments. Finally, our method is also capable of delivering improved calibration performance than other methods, showing its suitability for safety-critical applications, including health-care. We hope that our contributions would instigate more DG research across the medical imaging community. Code is available at github.com/Chumsy0725/SPSD-ViT.