Traditional post-training quantization (PTQ) is considered an effective approach to reduce model size and accelerate inference of large-scale language models (LLMs). However, existing low-rank PTQ methods require costly fine-tuning to determine a compromise rank for diverse data and layers in large models, failing to exploit their full potential. Additionally, the current SVD-based low-rank approximation compounds the computational overhead. In this work, we thoroughly analyze the varying effectiveness of low-rank approximation across different layers in representative models. Accordingly, we introduce Flexible Low-Rank Quantization (FLRQ), a novel solution designed to quickly identify the accuracy-optimal ranks and aggregate them to achieve minimal storage combinations. FLRQ comprises two powerful components, Rank1-Sketch-based Flexible Rank Selection (R1-FLR) and Best Low-rank Approximation under Clipping (BLC). R1-FLR applies the R1-Sketch with Gaussian projection for the fast low-rank approximation, enabling outlier-aware rank extraction for each layer. Meanwhile, BLC aims at minimizing the low-rank quantization error under the scaling and clipping strategy through an iterative method. FLRQ demonstrates strong effectiveness and robustness in comprehensive experiments, achieving state-of-the-art performance in both quantization quality and algorithm efficiency.

Brain simulation builds dynamical models to mimic the structure and functions of the brain, while brain-inspired computing (BIC) develops intelligent systems by learning from the structure and functions of the brain. The two fields are intertwined and should share a common programming framework to facilitate each other's development. However, none of the existing software in the fields can achieve this goal, because traditional brain simulators lack differentiability for training, while existing deep learning (DL) frameworks fail to capture the biophysical realism and complexity of brain dynamics. In this paper, we introduce BrainPy, a differentiable brain simulator developed using JAX and XLA, with the aim of bridging the gap between brain simulation and BIC. BrainPy expands upon the functionalities of JAX, a powerful AI framework, by introducing complete capabilities for flexible, efficient, and scalable brain simulation. It offers a range of sparse and event-driven operators for efficient and scalable brain simulation, an abstraction for managing the intricacies of synaptic computations, a modular and flexible interface for constructing multi-scale brain models, and an object-oriented just-in-time compilation approach to handle the memory-intensive nature of brain dynamics. We showcase the efficiency and scalability of BrainPy on benchmark tasks, and highlight its differentiable simulation for biologically plausible spiking models.