We study the quantum-classical polynomial hierarchy, QCPH, which is the class of languages solvable by a constant number of alternating classical quantifiers followed by a quantum verifier. Our main result is that QCPH is infinite relative to a random oracle (previously, this was not even known relative to any oracle). We further prove that higher levels of PH are not contained in lower levels of QCPH relative to a random oracle; this is a strengthening of the somewhat recent result that PH is infinite relative to a random oracle (Rossman, Servedio, and Tan 2016). The oracle separation requires lower bounding a certain type of low-depth alternating circuit with some quantum gates. To establish this, we give a new switching lemma for quantum algorithms which may be of independent interest. Our lemma says that for any $d$, if we apply a random restriction to a function $f$ with quantum query complexity $\mathrm{Q}(f)\le n^{1/3}$, the restricted function becomes exponentially close (in terms of $d$) to a depth-$d$ decision tree. Our switching lemma works even in a "worst-case" sense, in that only the indices to be restricted are random; the values they are restricted to are chosen adversarially. Moreover, the switching lemma also works for polynomial degree in place of quantum query complexity.

The Polynomial-Time Hierarchy ($\mathsf{PH}$) is a staple of classical complexity theory, with applications spanning randomized computation to circuit lower bounds to ''quantum advantage'' analyses for near-term quantum computers. Quantumly, however, despite the fact that at least \emph{four} definitions of quantum $\mathsf{PH}$ exist, it has been challenging to prove analogues for these of even basic facts from $\mathsf{PH}$. This work studies three quantum-verifier based generalizations of $\mathsf{PH}$, two of which are from [Gharibian, Santha, Sikora, Sundaram, Yirka, 2022] and use classical strings ($\mathsf{QCPH}$) and quantum mixed states ($\mathsf{QPH}$) as proofs, and one of which is new to this work, utilizing quantum pure states ($\mathsf{pureQPH}$) as proofs. We first resolve several open problems from [GSSSY22], including a collapse theorem and a Karp-Lipton theorem for $\mathsf{QCPH}$. Then, for our new class $\mathsf{pureQPH}$, we show one-sided error reduction for $\mathsf{pureQPH}$, as well as the first bounds relating these quantum variants of $\mathsf{PH}$, namely $\mathsf{QCPH}\subseteq \mathsf{pureQPH} \subseteq \mathsf{EXP}^{\mathsf{PP}}$.