Leveraging the visual priors of pre-trained text-to-image diffusion models offers a promising solution to enhance zero-shot generalization in dense prediction tasks. However, existing methods often uncritically use the original diffusion formulation, which may not be optimal due to the fundamental differences between dense prediction and image generation. In this paper, we provide a systemic analysis of the diffusion formulation for the dense prediction, focusing on both quality and efficiency. And we find that the original parameterization type for image generation, which learns to predict noise, is harmful for dense prediction; the multi-step noising/denoising diffusion process is also unnecessary and challenging to optimize. Based on these insights, we introduce $\textbf{Lotus}$, a diffusion-based visual foundation model with a simple yet effective adaptation protocol for dense prediction. Specifically, Lotus is trained to directly predict annotations instead of noise, thereby avoiding harmful variance. We also reformulate the diffusion process into a single-step procedure, simplifying optimization and significantly boosting inference speed. Additionally, we introduce a novel tuning strategy called detail preserver, which achieves more accurate and fine-grained predictions. Without scaling up the training data or model capacity, Lotus achieves SoTA performance in zero-shot depth and normal estimation across various datasets. It also enhances efficiency, being significantly faster than most existing diffusion-based methods. Lotus' superior quality and efficiency also enable a wide range of practical applications, such as joint estimation, single/multi-view 3D reconstruction, etc.

Current perceptive models heavily depend on resource-intensive datasets, prompting the need for innovative solutions. Leveraging recent advances in diffusion models, synthetic data, by constructing image inputs from various annotations, proves beneficial for downstream tasks. While prior methods have separately addressed generative and perceptive models, DetDiffusion, for the first time, harmonizes both, tackling the challenges in generating effective data for perceptive models. To enhance image generation with perceptive models, we introduce perception-aware loss (P.A. loss) through segmentation, improving both quality and controllability. To boost the performance of specific perceptive models, our method customizes data augmentation by extracting and utilizing perception-aware attribute (P.A. Attr) during generation. Experimental results from the object detection task highlight DetDiffusion's superior performance, establishing a new state-of-the-art in layout-guided generation. Furthermore, image syntheses from DetDiffusion can effectively augment training data, significantly enhancing downstream detection performance.