Abstract The role of medical test results in the diagnosis and treatment of a patient’s disease cannot be denied. Doctors and medical staff rely on these results to develop a treatment plan that meets the requirements of the patient’s health status (i.e., physical condition) and disease type. In developing countries (i.e., Vietnam), we note that test results are recorded in paper versions and stored by patients. Thus, several solutions have been introduced for electronic medical records to compensate for medical test results management. However, in Vietnam, these approaches face many obstacles such as centralized processing (e.g., storage, analysis); non-transparency issues; scalability; availability; and so on. In this paper, we exploit the benefits of blockchain, smart contracts, and NFT technologies to solve the above disadvantages. Therefore, our work contributes to five aspects. (a) Collecting procedures for handling and storing test results of patients at hospitals in Ho Chi Minh City and Mekong Delta (i.e., Can Tho city) (b) Proposing a mechanism for sharing test results based on blockchain technology, smart contract, and NFT applied; (c) Presenting an NFT tool-based certification generation model; (d) implementing the proposed model based on smart contracts (i.e., proof-of-concept); and (e) deploying proof-of-concept on four EVM- and NFT-supported platforms to find the most suitable one.