Recent advances in deep learning have led to significant improvements in nuclei segmentation from histological images, particularly when labels of all classes are available simultaneously during training. However, in clinical practice, real-world scenarios require a model to perform well in an incremental learning setting, where we anticipate the model to achieve satisfactory performance on previously unseen data while effectively mitigating catastrophic forgetting of old classes. Most previous methods alleviate forgetting by distilling old class knowledge through prototypes; however, they fail to adequately capture fine-grained details to address the challenge of high class similarity, which is particularly severe in histological images. To overcome these limitations, we propose a novel incremental learning method for nuclei segmentation (we call it CiNuSeg), which is composed of two key innovative modules. First, we propose a new Anchor-driven Consistency Learning (ACL) module to construct multi-level class anchors within each sample to effectively capture fine structural and textural details of nuclei, thereby significantly mitigating forgetting. Second, we develop a Dual Region Regularization (DRR) module to suppress new class representations within old class regions while enhancing new class representations within new class regions, strengthening the model's ability to discriminate between different nuclei types and improving inter-class separability. We further introduce an Adaptive Temperature Tuning (ATT) strategy to dynamically balance model stability and plasticity. Extensive experiments conducted on benchmarking MoNuSAC and CoNSeP pathological datasets demonstrate the effectiveness of our method, consistently achieving better performance than SOTAs in different settings. Codes will be available upon publication.

Accurate automatic breast ultrasound (BUS) image segmentation is essential for early breast cancer screening and diagnosis. However, it remains challenging owing to (1) breast lesions of various scale and shape, (2) ambiguous boundaries caused by speckle noise and artifacts, and (3) the scarcity of high-quality annotations. Most existing semi-supervised methods employ the mean-teacher architecture, which merely learns semantic information within a single image and heavily relies on the performance of the teacher model. Therefore, we present a novel cross-image semantic correlation semi-supervised framework, named CSC-PA, to improve the performance of BUS image segmentation. CSC-PA is trained based on a single network, which integrates a foreground prototype attention (FPA) and an edge prototype attention (EPA). Specifically, FPA transfers complementary foreground information for more stable and complete lesion segmentation. On the other hand, EPA enhances edge features of lesions by using edge prototype, where an adaptive edge container is proposed to store global edge features and generate the edge prototype. Additionally, we introduce a pixel affinity loss (PAL) to exploit previously ignored contextual correlation in supervision, which further improves performance on edges. Extensive experiments on two benchmark BUS datasets demonstrate that our model outperforms other state-of-the-art methods under different partition protocols. Codes are available at https://github.com/shdkdh/CSC-PA.

Co-salient object detection (CoSOD) aims to detect common salient objects across multiple related images. However, existing methods often struggle with limited attention coverage, missing some co-salient objects. To address this, we propose a two-stage feature processing module (FPM) comprising comprehensive feature extraction module (CFE) and feature enhancement module (FEM). CFE extracts comprehensive cosalient features while reducing background noise, and FEM enhances feature representation and adjusts attention weights for full object coverage. Additionally, we introduce an adversarial learning module (ALM) to improve prediction quality by reducing noise in the co-salient regions. Extensive experiments on three benchmark datasets—CoCA, CoSOD3k, and CoSal2015—demonstrate that our model significantly outperforms state-of-the-art methods. The source code is available at https://github.com/yaobaimiao/CFPAM.