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Silke R. Sperling

dblp:40/7969 · DBLP profile ↗
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1ranked-venue papers
0as first author
0since 2021 · last 2010
0000-0002-7135-3298ORCID · reported

Domains — the database's venue-derived domains; a paper can count in several

Applied, interdisciplinary, general and emerging computing · 1

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
1 paper
Bioinformatics and computational biology · 100%

Topics — the 2 heaviest of 2, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Bioinformatics and computational biology
sequence alignment
0.112010
MicroRazerS: rapid alignment of small RNA reads · Bioinform. 2010
Bioinformatics and computational biology › sequence analysis › high-throughput sequencing data analysis
deep sequencing data analysis
0.012010
MicroRazerS: rapid alignment of small RNA reads · Bioinform. 2010

Methods — techniques the papers use, named apart from their topics

short read alignment · 0.1
YearPublicationVenuePosition
2010 MicroRazerS: rapid alignment of small RNA reads
abstract
MOTIVATION: Deep sequencing has become the method of choice for determining the small RNA content of a cell. Mapping the sequenced reads onto their reference genome serves as the basis for all further analyses, namely for identification and quantification. A method frequently used is Mega BLAST followed by several filtering steps, even though it is slow and inefficient for this task. Also, none of the currently available short read aligners has established itself for the particular task of small RNA mapping. RESULTS: We present MicroRazerS, a tool optimized for mapping small RNAs onto a reference genome. It is an order of magnitude faster than Mega BLAST and comparable in speed with other short read mapping tools. In addition, it is more sensitive and easy to handle and adjust. AVAILABILITY: MicroRazerS is part of the SeqAn C++ library and can be downloaded from http://www.seqan.de/projects/MicroRazerS.html.
Anne-Katrin Emde, Marcel Grunert, David Weese, Knut Reinert, Silke R. Sperling
Bioinform.5