The Noise2Noise method allows for training machine learning-based denoisers with pairs of input and target images where both the input and target can be noisy. This removes the need for training with clean target images, which can be difficult to obtain. However, Noise2Noise training has a major limitation: nonlinear functions applied to the noisy targets will skew the results. This bias occurs because the nonlinearity makes the expected value of the noisy targets different from the clean target image. Since nonlinear functions are common in image processing, avoiding them limits the types of preprocessing that can be performed on the noisy targets. Our main insight is that certain nonlinear functions can be applied to the noisy targets without adding significant bias to the results. We develop a theoretical framework for analyzing the effects of these nonlinearities, and describe a class of nonlinear functions with minimal bias.