VLDB 2026 Research / reviewers in the wild / expert
Xin Yang 0009
dblp:44/1152-9
· DBLP profile ↗
77ranked-venue papers
9as first author
49since 2021 · last 2026
0000-0003-4653-6524ORCID · conflict
Domains — the database's venue-derived domains; a paper can count in several
Applied, interdisciplinary, general and emerging computing · 69 · 8 first-author · 44 since 2021Graphics, computer vision, multimedia, augmented reality and games · 37 · 4 first-author · 23 since 2021Artificial intelligence and machine learning · 7 · 1 first-author · 5 since 2021Human-computer interaction and ubiquitous computing · 1
| Year | Publication | Venue | Position |
|---|---|---|---|
| 2026 | OnUVS: An Online Motion Transfer Framework With Content-Texture Decoupling for High-Fidelity Ultrasound Video SynthesisabstractUltrasound (US) imaging plays a crucial role in diagnosing heart and pelvic diseases, where sonographers tend to evaluate dynamic motion and structure. However, the scarcity of US videos for rare cases limitstraining opportunities for novice sonographers and deep learning models, hindering detection rates and clinical diagnostic applications. US video synthesis is a promising solution to this issue. Nevertheless, accurately imitating the intricate motion of the anatomy while preserving image fidelity presents asignificant challenge. In this work, we propose OnUVS, a novel online feature-decoupling framework for high-fidelity US video synthesis. First, to simulate realistic motion, we incorporate keypoints into anatomical learning through a weakly supervised training approach, which enhances motion representation and minimizes the need for fully annotated data. Second, we implement a dual-decoder generator that effectively balances content and textural features of generated frames, significantly enhancing the image fidelity of US videos. Third, a multi-scale discriminator further refines the sharpness and fine details, ensuring high-fidelity video synthesis. Fourth, an online learning strategy is designed to smooth coherence between frames by constraining the keypoint trajectories during inference. Validation on echocardiographic and pelvic floor US datasets demonstrates that OnUVS outperforms existing methods, achieving a 22.08% improvement in motion consistency (FVD) and 25.04% in image fidelity (FID). Rusi Chen, Xin Yang 0009, Ao Chang, Junxuan Yu, Yuhao Huang 0001, Ruobing Huang, Luping Zhou, Jiamin Liang, Haoran Dou, Yongsong Zhou, Mengyun Qiao, Deng-Ping Fan, Hongkui Yu, Dong Ni 0001, Zhongshan Gou |
IEEE J. Biomed. Health Informatics | 3 |
| 2025 | MTCNet: Motion and Topology Consistency Guided Learning for Mitral Valve Segmentation in 4D Ultrasound
Rusi Chen, Yuanting Yang, Jiezhi Yao, Hongning Song, Yongsong Zhou, Yuhao Huang 0001, Ronghao Yang, Dan Jia, Xing Tao, Haoran Dou, Xin Yang 0009, Dong Ni 0001 |
MICCAI (3) | 14 |
| 2025 | ADAptation: Reconstruction-Based Unsupervised Active Learning for Breast Ultrasound Diagnosis
Yaofei Duan, Yuhao Huang 0001, Xin Yang 0009, Luyi Han, Xinyu Xie, Ka-Hou Chan, Ligang Cui, Sio Kei Im, Dong Ni 0001, Tao Tan 0002 |
MICCAI (16) | 3 |
| 2025 | Uncertainty-Aware Diffusion and Reinforcement Learning for Joint Plane Localization and Anomaly Diagnosis in 3D Ultrasound
Yuhao Huang 0001, Yueyue Xu, Haoran Dou, Jiaxiao Deng, Xin Yang 0009, Dong Ni 0001 |
MICCAI (4) | 5 |
| 2025 | Medical-Knowledge Driven Multiple Instance Learning for Classifying Severe Abdominal Anomalies on Prenatal Ultrasound
Huanwen Liang, Jingxian Xu, Yuanji Zhang, Yuhao Huang 0001, Xin Yang 0009, Xuedong Deng, Guowei Tao, Xinru Gao, Dong Ni 0001 |
MICCAI (3) | 6 |
| 2025 | MReg: A Novel Regression Model with MoE-Based Video Feature Mining for Mitral Regurgitation Diagnosis
Yuhao Huang 0001, Chengrui Zhang, Haotian Lin 0009, Tong Han, Ruiyue Chen, Dong Ni 0001, Zhongshan Gou, Xin Yang 0009 |
MICCAI (9) | 12 |
| 2025 | Accurate and Efficient Fetal Birth Weight Estimation from 3D Ultrasound
Jian Wang 0099, Qiongying Ni, Hongkui Yu, Ruixuan Yao, Jinqiao Ying, Xingyi Yang, Jiongquan Chen, Junxuan Yu, Wenlong Shi, Chaoyu Chen, Zhongnuo Yan, Mingyuan Luo, Gaocheng Cai, Dong Ni 0001, Xin Yang 0009 |
MICCAI (1) | 18 |
| 2025 | UltraTwin: Towards Cardiac Anatomical Twin Generation from Multi-view 2D Ultrasound
Junxuan Yu, Yaofei Duan, Yuhao Huang 0001, Rongbo Ling, Weihao Luo, Jingxian Xu, Qiongying Ni, Yongsong Zhou, Binghan Li, Haoran Dou, Yanfen Chu, Feng Geng, Zhe Sheng, Zhifeng Ding, Yuhang Zhang 0034, Tao Tan 0002, Dong Ni 0001, Zhongshan Gou, Xin Yang 0009 |
MICCAI (16) | 25 |
| 2025 | Hierarchical Corpus-View-Category Refinement for Carotid Plaque Risk Grading in Ultrasound
Jian Wang 0099, Tong Han, Yuhao Huang 0001, Mingyuan Luo, Yaofei Duan, Dong Ni 0001, Tianhong Tang, Xin Yang 0009 |
MICCAI (13) | 13 |
| 2025 | FetalFlex: Anatomy-guided diffusion model for flexible control on fetal ultrasound image synthesis
Yaofei Duan, Tao Tan 0002, Yuhao Huang 0001, Yuanji Zhang, Patrick Pang 0001, Xinru Gao, Guowei Tao, Xiang Cong, Lianying Liang, Guangzhi He, Linliang Yin, Xuedong Deng, Xin Yang 0009, Dong Ni 0001 |
Medical Image Anal. | 16 |
| 2025 | An orchestration learning framework for ultrasound imaging: Prompt-Guided Hyper-Perception and Attention-Matching Downstream Synchronization
Shuo Li 0001, Shanshan Wang 0010, Zhifan Gao, Yue Sun 0001, Chan-Tong Lam, Xindi Hu, Xin Yang 0009, Dong Ni 0001, Tao Tan 0002 |
Medical Image Anal. | 8 |
| 2025 | Enhancing lesion detection in automated breast ultrasound using unsupervised multi-view contrastive learning with 3D DETR
Xing Tao, Yan Cao 0002, Yanhui Jiang, Xiaoxi Wu, Dan Yan, Shulian Zhuang, Xin Yang 0009, Ruobing Huang, Jianxing Zhang, Dong Ni 0001 |
Medical Image Anal. | 8 |
| 2025 | P2ED: A four-quadrant framework for progressive prompt enhancement in 3D interactive medical imaging segmentation
Ao Chang, Xing Tao, Yuhao Huang 0001, Xin Yang 0009, Jiajun Zeng, Ruobing Huang, Dong Ni 0001 |
Neural Networks | 4 |
| 2025 | MoNetV2: Enhanced Motion Network for Freehand 3-D Ultrasound ReconstructionabstractThree-dimensional ultrasound (US) aims to provide sonographers with the spatial relationships of anatomical structures, playing a crucial role in clinical diagnosis. Recently, deep-learning-based freehand 3-D US has made significant advancements. It reconstructs volumes by estimating transformations between images without external tracking. However, image-only reconstruction poses difficulties in reducing cumulative drift and further improving reconstruction accuracy, particularly in scenarios involving complex motion trajectories. In this context, we propose an enhanced motion network (MoNetV2) to enhance the accuracy and generalizability of reconstruction under diverse scanning velocities and tactics. First, we propose a sensor-based temporal and multibranch structure (TMS) that fuses image and motion information from a velocity perspective to improve image-only reconstruction accuracy. Second, we devise an online multilevel consistency constraint (MCC) that exploits the inherent consistency of scans to handle various scanning velocities and tactics. This constraint exploits scan-level velocity consistency (SVC), path-level appearance consistency (PAC), and patch-level motion consistency (PMC) to supervise interframe transformation estimation. Third, we distill an online multimodal self-supervised strategy (MSS) that leverages the correlation between network estimation and motion information to further reduce cumulative errors. Extensive experiments clearly demonstrate that MoNetV2 surpasses existing methods in both reconstruction quality and generalizability performance across three large datasets. Mingyuan Luo, Xin Yang 0009, Zhongnuo Yan, Yan Cao 0002, Yuanji Zhang, Xindi Hu, Haoxuan Ding, Dong Ni 0001 |
IEEE Trans. Neural Networks Learn. Syst. | 2 |
| 2024 | UniUSNet: A Promptable Framework for Universal Ultrasound Disease Prediction and Tissue SegmentationabstractUltrasound is widely used in clinical practice due to its affordability, portability, and safety. However, current AI research often overlooks combined disease prediction and tissue segmentation. We propose UniUSNet, a universal framework for ultrasound image classification and segmentation. This model handles various ultrasound types, anatomical positions, and input formats, excelling in both segmentation and classification tasks. Trained on a comprehensive dataset with over 9.7K annotations from 7 distinct anatomical positions, our model matches state-of-the-art performance and surpasses single-dataset and ablated models. Zero-shot and fine-tuning experiments show strong generalization and adaptability with minimal fine-tuning. We plan to expand our dataset and refine the prompting mechanism, with model weights and code available at (https://github.com/Zehui-Lin/UniUSNet). Zhuoneng Zhang, Xindi Hu, Zhifan Gao, Xin Yang 0009, Yue Sun 0001, Dong Ni 0001, Tao Tan 0002 |
BIBM | 5 |
| 2024 | Fine-Grained Context and Multi-modal Alignment for Freehand 3D Ultrasound Reconstruction
Zhongnuo Yan, Xin Yang 0009, Mingyuan Luo, Jiongquan Chen, Rusi Chen, Dong Ni 0001 |
MICCAI (7) | 2 |
| 2024 | FetusMapV2: Enhanced fetal pose estimation in 3D ultrasound
Chaoyu Chen, Xin Yang 0009, Yuhao Huang 0001, Wenlong Shi, Yan Cao 0002, Mingyuan Luo, Xindi Hu, Lei Zhu 0003, Lequan Yu, Kejuan Yue, Yuanji Zhang, Yi Xiong 0001, Dong Ni 0001, Weijun Huang |
Medical Image Anal. | 2 |
| 2024 | Segment anything model for medical images?
Yuhao Huang 0001, Xin Yang 0009, Ao Chang, Rusi Chen, Junxuan Yu, Jiongquan Chen, Chaoyu Chen, Sijing Liu, Haozhe Chi, Xindi Hu, Kejuan Yue, Lei Li 0020, Vicente Grau, Deng-Ping Fan, Fajin Dong, Dong Ni 0001 |
Medical Image Anal. | 2 |
| 2024 | Hierarchical online contrastive anomaly detection for fetal arrhythmia diagnosis in ultrasound
Xin Yang 0009, Zhongnuo Yan, Junxuan Yu, Xindi Hu, Xuejuan Yu, Caixia Dong, Ju Chen, Zhuan Yu, Xuedong Deng, Dong Ni 0001, Xiaoqiong Huang, Zhongshan Gou |
Medical Image Anal. | 1 |
| 2024 | PR-PL: A Novel Prototypical Representation Based Pairwise Learning Framework for Emotion Recognition Using EEG SignalsabstractAffective brain-computer interface based on electroencephalography (EEG) is an important branch in the field of affective computing. However, the individual differences in EEG emotional data and the noisy labeling problem in the subjective feedback seriously limit the effectiveness and generalizability of existing models. To tackle these two critical issues, we propose a novel transfer learning framework with Prototypical Representation based Pairwise Learning (PR-PL). The discriminative and generalized EEG features are learned for emotion revealing across individuals and the emotion recognition task is formulated as pairwise learning for improving the model tolerance to the noisy labels. More specifically, a prototypical learning is developed to encode the inherent emotion-related semantic structure of EEG data and align the individuals' EEG features to a shared common feature space under consideration of the feature separability of both source and target domains. Based on the aligned feature representations, pairwise learning with an adaptive pseudo labeling method is introduced to encode the proximity relationships among samples and alleviate the label noises effect on modeling. Extensive results on two benchmark databases (SEED and SEED-IV) under four different cross-validation evaluation protocols validate the model reliability and stability across subjects and sessions. Compared to the literature, the average enhancement of emotion recognition across four different evaluation protocols is 2.04% (SEED) and 2.58% (SEED-IV). The source code is available athttps://github.com/KAZABANA/PR-PL. Rushuang Zhou, Zhiguo Zhang 0001, Hong Fu, Li Zhang 0041, Linling Li, Fali Li, Xin Yang 0009, Yining Dong, Yuan-Ting Zhang |
IEEE Trans. Affect. Comput. | 8 |
| 2023 | GSMorph: Gradient Surgery for Cine-MRI Cardiac Deformable Registration
Haoran Dou, Ning Bi, Luyi Han, Yuhao Huang 0001, Ritse Mann, Xin Yang 0009, Dong Ni 0001, Nishant Ravikumar, Alejandro F. Frangi, Yunzhi Huang |
MICCAI (10) | 6 |
| 2023 | Fourier Test-Time Adaptation with Multi-level Consistency for Robust Classification
Yuhao Huang 0001, Xin Yang 0009, Xiaoqiong Huang, Haozhe Chi, Haoran Dou, Xindi Hu, Jian Wang 0099, Xuedong Deng, Dong Ni 0001 |
MICCAI (3) | 2 |
| 2023 | Instructive Feature Enhancement for Dichotomous Medical Image Segmentation
Jiongquan Chen, Sijing Liu, Wenlong Shi, Dong Ni 0001, Deng-Ping Fan, Xin Yang 0009 |
MICCAI (4) | 8 |
| 2023 | Multi-IMU with Online Self-consistency for Freehand 3D Ultrasound Reconstruction
Mingyuan Luo, Xin Yang 0009, Zhongnuo Yan, Yuanji Zhang, Jiongquan Chen, Xindi Hu, Jikuan Qian, Jun Cheng 0006, Dong Ni 0001 |
MICCAI (1) | 2 |
| 2023 | Inflated 3D Convolution-Transformer for Weakly-Supervised Carotid Stenosis Grading with Ultrasound Videos
Yuhao Huang 0001, Wufeng Xue, Xin Yang 0009, Yuxin Zou, Qilong Ying, Yuanji Zhang, Dong Ni 0001 |
MICCAI (2) | 4 |
| 2023 | RecON: Online learning for sensorless freehand 3D ultrasound reconstruction
Mingyuan Luo, Xin Yang 0009, Hongzhang Wang, Haoran Dou, Xindi Hu, Yuhao Huang 0001, Nishant Ravikumar, Songcheng Xu, Yuanji Zhang, Yi Xiong 0001, Wufeng Xue, Alejandro F. Frangi, Dong Ni 0001 |
Medical Image Anal. | 2 |
| 2022 | Generalizable Cross-modality Medical Image Segmentation via Style Augmentation and Dual NormalizationabstractFor medical image segmentation, imagine if a model was only trained using MR images in source domain, how about its performance to directly segment CT images in target domain? This setting, namely generalizable cross-modality segmentation, owning its clinical potential, is much more challenging than other related settings, e.g., domain adaptation. To achieve this goal, we in this paper propose a novel dual-normalization model by leveraging the augmented source-similar and source-dissimilar images during our generalizable segmentation. To be specific, given a single source domain, aiming to simulate the possible appearance change in unseen target domains, we first utilize a nonlinear transformation to augment source-similar and source-dissimilar images. Then, to sufficiently exploit these two types of augmentations, our proposed dualnormalization based model employs a shared backbone yet independent batch normalization layer for separate normalization. Afterward, we put forward a style-based selection scheme to automatically choose the appropriate path in the test stage. Extensive experiments on three publicly available datasets, i.e., BraTS, Cross-Modality Cardiac, and Abdominal Multi-Organ datasets, have demonstrated that our method outperforms other state-of-the-art domain generalization methods. Code is available at https://github.com/zzzqzhou/Dual-Normalization. Lei Qi 0001, Xin Yang 0009, Dong Ni 0001, Yinghuan Shi |
CVPR | 3 |
| 2022 | Fine-Grained Correlation Loss for Regression
Chaoyu Chen, Xin Yang 0009, Ruobing Huang, Xindi Hu, Yankai Huang, Xiduo Lu, Mingyuan Luo, Yinyu Ye 0002, Xue Shuang, Juzheng Miao, Yi Xiong 0001, Dong Ni 0001 |
MICCAI (8) | 2 |
| 2022 | Online Reflective Learning for Robust Medical Image Segmentation
Yuhao Huang 0001, Xin Yang 0009, Xiaoqiong Huang, Jiamin Liang, Cheng Chen 0013, Haoran Dou, Xindi Hu, Yan Cao 0002, Dong Ni 0001 |
MICCAI (8) | 2 |
| 2022 | Weakly-Supervised High-Fidelity Ultrasound Video Synthesis with Feature Decoupling
Jiamin Liang, Xin Yang 0009, Yuhao Huang 0001, Xindi Hu, Huanjia Luo, Yuanji Zhang, Yi Xiong 0001, Dong Ni 0001 |
MICCAI (4) | 2 |
| 2022 | Deep Motion Network for Freehand 3D Ultrasound Reconstruction
Mingyuan Luo, Xin Yang 0009, Hongzhang Wang, Liwei Du, Dong Ni 0001 |
MICCAI (4) | 2 |
| 2022 | Agent with Tangent-Based Formulation and Anatomical Perception for Standard Plane Localization in 3D Ultrasound
Yuxin Zou, Haoran Dou, Yuhao Huang 0001, Xin Yang 0009, Jikuan Qian, Chaojiong Zhen, Xiaodan Ji, Nishant Ravikumar, Weijun Huang, Alejandro F. Frangi, Dong Ni 0001 |
MICCAI (4) | 4 |
| 2022 | HASA: Hybrid architecture search with aggregation strategy for echinococcosis classification and ovary segmentation in ultrasound images
Jikuan Qian, Rui Li 0038, Xin Yang 0009, Yuhao Huang 0001, Mingyuan Luo, Wenhui Hong, Ruobing Huang, Haining Fan, Dong Ni 0001, Jun Cheng 0006 |
Expert Syst. Appl. | 3 |
| 2022 | Boundary-rendering network for breast lesion segmentation in ultrasound images
Ruobing Huang, Mingrong Lin, Haoran Dou, Qilong Ying, Xiaohong Jia 0003, Zihan Mei, Xin Yang 0009, Yijie Dong, Jianqiao Zhou, Dong Ni 0001 |
Medical Image Anal. | 9 |
| 2022 | Sketch guided and progressive growing GAN for realistic and editable ultrasound image synthesis
Jiamin Liang, Xin Yang 0009, Yuhao Huang 0001, Haoming Li 0008, Shuangchi He, Xindi Hu, Zejian Chen, Wufeng Xue, Jun Cheng 0006, Dong Ni 0001 |
Medical Image Anal. | 2 |
| 2022 | AWSnet: An auto-weighted supervision attention network for myocardial scar and edema segmentation in multi-sequence cardiac magnetic resonance images
Kai-Ni Wang, Xin Yang 0009, Juzheng Miao, Lei Li 0020, Wufeng Xue, Guangquan Zhou, Xiahai Zhuang, Dong Ni 0001 |
Medical Image Anal. | 2 |
| 2022 | Joint Landmark and Structure Learning for Automatic Evaluation of Developmental Dysplasia of the HipabstractThe ultrasound (US) screening of the infant hip is vital for the early diagnosis of developmental dysplasia of the hip (DDH). The US diagnosis of DDH refers to measuring alpha and beta angles that quantify hip joint development. These two angles are calculated from key anatomical landmarks and structures of the hip. However, this measurement process is not trivial for sonographers and usually requires a thorough understanding of complex anatomical structures. In this study, we propose a multi-task framework to learn the relationships among landmarks and structures jointly and automatically evaluate DDH. Our multi-task networks are equipped with three novel modules. Firstly, we adopt Mask R-CNN as the basic framework to detect and segment key anatomical structures and add one landmark detection branch to form a new multi-task framework. Secondly, we propose a novel shape similarity loss to refine the incomplete anatomical structure prediction robustly and accurately. Thirdly, we further incorporate the landmark-structure consistent prior to ensure the consistency of the bony rim estimated from the segmented structure and the detected landmark. In our experiments, 1231 US images of the infant hip from 632 patients are collected, of which 247 images from 126 patients are tested. The average errors in alpha and beta angles are 2.221${}^{\circ }$and 2.899${}^{\circ }$. About 93% and 85% estimates of alpha and beta angles have errors less than 5 degrees, respectively. Experimental results demonstrate that the proposed method can accurately and robustly realize the automatic evaluation of DDH, showing great potential for clinical application. Xindi Hu, Xin Yang 0009, Xu Zhou 0005, Wufeng Xue, Yan Cao 0002, Shengfeng Liu, Yuhao Huang 0001, Shuangping Guo, Dong Ni 0001, Ning Gu 0003 |
IEEE J. Biomed. Health Informatics | 3 |
| 2021 | Flip Learning: Erase to Segment
Yuhao Huang 0001, Xin Yang 0009, Yuxin Zou, Chaoyu Chen, Jian Wang 0099, Haoran Dou, Nishant Ravikumar, Alejandro F. Frangi, Jianqiao Zhou, Dong Ni 0001 |
MICCAI (1) | 2 |
| 2021 | Style Curriculum Learning for Robust Medical Image Segmentation
Manh The Van, Xin Yang 0009, Xiaoqiong Huang, Karim Lekadir, Víctor M. Campello, Nishant Ravikumar, Alejandro F. Frangi, Dong Ni 0001 |
MICCAI (1) | 3 |
| 2021 | Self Context and Shape Prior for Sensorless Freehand 3D Ultrasound Reconstruction
Mingyuan Luo, Xin Yang 0009, Xiaoqiong Huang, Yuhao Huang 0001, Yuxin Zou, Xindi Hu, Nishant Ravikumar, Alejandro F. Frangi, Dong Ni 0001 |
MICCAI (6) | 2 |
| 2021 | AW3M: An auto-weighting and recovery framework for breast cancer diagnosis using multi-modal ultrasound
Ruobing Huang, Haoran Dou, Jian Wang 0099, Juzheng Miao, Guangquan Zhou, Xiaohong Jia 0003, Zihan Mei, Yijie Dong, Xin Yang 0009, Jianqiao Zhou, Dong Ni 0001 |
Medical Image Anal. | 11 |
| 2021 | A global benchmark of algorithms for segmenting the left atrium from late gadolinium-enhanced cardiac magnetic resonance imaging
Zhaohan Xiong, Qing Xia 0002, Cheng Bian, Yefeng Zheng 0001, Sulaiman Vesal, Nishant Ravikumar, Andreas K. Maier, Xin Yang 0009, Pheng-Ann Heng, Dong Ni 0001, Caizi Li, Qianqian Tong 0001, Weixin Si, Élodie Puybareau, Younes Khoudli, Thierry Géraud, Jichao Zhao |
Medical Image Anal. | 10 |
| 2021 | Modality alignment contrastive learning for severity assessment of COVID-19 from lung ultrasound and clinical information
Wufeng Xue, Chunyan Cao, Yilian Duan, Haiyan Cao, Jian Wang 0099, Xumin Tao, Zejian Chen, Jinxiang Zhang, Xin Yang 0009, Ruobing Huang, Feixiang Xiang, Manjie You, Mingxing Xie |
Medical Image Anal. | 13 |
| 2021 | Searching collaborative agents for multi-plane localization in 3D ultrasound
Xin Yang 0009, Yuhao Huang 0001, Ruobing Huang, Haoran Dou, Rui Li 0038, Jikuan Qian, Xiaoqiong Huang, Wenlong Shi, Chaoyu Chen, Yuanji Zhang, Yi Xiong 0001, Dong Ni 0001 |
Medical Image Anal. | 1 |
| 2021 | Contrastive rendering with semi-supervised learning for ovary and follicle segmentation from 3D ultrasound
Xin Yang 0009, Haoming Li 0008, Yi Wang 0031, Xiaowen Liang, Chaoyu Chen, Xu Zhou 0005, Fengyi Zeng, Jinghui Fang, Alejandro F. Frangi, Dong Ni 0001 |
Medical Image Anal. | 1 |
| 2021 | Learn Fine-Grained Adaptive Loss for Multiple Anatomical Landmark Detection in Medical ImagesabstractAutomatic and accurate detection of anatomical landmarks is an essential operation in medical image analysis with a multitude of applications. Recent deep learning methods have improved results by directly encoding the appearance of the captured anatomy with the likelihood maps (i.e., heatmaps). However, most current solutions overlook another essence of heatmap regression, the objective metric for regressing target heatmaps and rely on hand-crafted heuristics to set the target precision, thus being usually cumbersome and task-specific. In this paper, we propose a novel learning-to-learn framework for landmark detection to optimize the neural network and the target precision simultaneously. The pivot of this work is to leverage the reinforcement learning (RL) framework to search objective metrics for regressing multiple heatmaps dynamically during the training process, thus avoiding setting problem-specific target precision. We also introduce an early-stop strategy for active termination of the RL agent's interaction that adapts the optimal precision for separate targets considering exploration-exploitation tradeoffs. This approach shows better stability in training and improved localization accuracy in inference. Extensive experimental results on two different applications of landmark localization: 1) our in-house prenatal ultrasound (US) dataset and 2) the publicly available dataset of cephalometric X-Ray landmark detection, demonstrate the effectiveness of our proposed method. Our proposed framework is general and shows the potential to improve the efficiency of anatomical landmark detection. Guangquan Zhou, Juzheng Miao, Xin Yang 0009, Rui Li 0038, En-Ze Huo, Wenlong Shi, Yuhao Huang 0001, Jikuan Qian, Chaoyu Chen, Dong Ni 0001 |
IEEE J. Biomed. Health Informatics | 3 |
| 2021 | Multi-Centre, Multi-Vendor and Multi-Disease Cardiac Segmentation: The M&Ms ChallengeabstractThe emergence of deep learning has considerably advanced the state-of-the-art in cardiac magnetic resonance (CMR) segmentation. Many techniques have been proposed over the last few years, bringing the accuracy of automated segmentation close to human performance. However, these models have been all too often trained and validated using cardiac imaging samples from single clinical centres or homogeneous imaging protocols. This has prevented the development and validation of models that are generalizable across different clinical centres, imaging conditions or scanner vendors. To promote further research and scientific benchmarking in the field of generalizable deep learning for cardiac segmentation, this paper presents the results of the Multi-Centre, Multi-Vendor and Multi-Disease Cardiac Segmentation (M&Ms) Challenge, which was recently organized as part of the MICCAI 2020 Conference. A total of 14 teams submitted different solutions to the problem, combining various baseline models, data augmentation strategies, and domain adaptation techniques. The obtained results indicate the importance of intensity-driven data augmentation, as well as the need for further research to improve generalizability towards unseen scanner vendors or new imaging protocols. Furthermore, we present a new resource of 375 heterogeneous CMR datasets acquired by using four different scanner vendors in six hospitals and three different countries (Spain, Canada and Germany), which we provide as open-access for the community to enable future research in the field. Víctor M. Campello, Polyxeni Gkontra, Cristian Izquierdo, Carlos Martín-Isla, Alireza Sojoudi, Peter M. Full, Klaus H. Maier-Hein, Yao Zhang 0010, Zhiqiang He 0002, Jun Ma 0016, Mario Parreño, Alberto Albiol, Fanwei Kong, Shawn C. Shadden, Jorge Corral Acero, Vaanathi Sundaresan, Mina Saber, Mustafa A. Alattar, Hongwei Li 0004, Bjoern Menze, Firas Khader, Christoph Haarburger, Cian M. Scannell, Mitko Veta, Adam Carscadden, Kumaradevan Punithakumar, Xiao Liu 0037, Sotirios A. Tsaftaris, Xiaoqiong Huang, Xin Yang 0009, Lei Li 0020, Xiahai Zhuang, David Viladés, Martín Luís Descalzo, Andrea Guala 0002, Lucia La Mura, Matthias G. W. Friedrich, Ria Garg, Julie Lebel, Filipe Henriques, Mahir Karakas, Ersin Çavus, Steffen E. Petersen, Sergio Escalera, Santi Seguí, Jose Rodriguez-Palomares, Karim Lekadir |
IEEE Trans. Medical Imaging | 30 |
| 2021 | A Deep Attentive Convolutional Neural Network for Automatic Cortical Plate Segmentation in Fetal MRIabstractFetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and time-consuming. Automatic segmentation of the cortical plate, on the other hand, is challenged by the relatively low resolution of the reconstructed fetal brain MRI scans compared to the thin structure of the cortical plate, partial voluming, and the wide range of variations in the morphology of the cortical plate as the brain matures during gestation. To reduce the burden of manual refinement of segmentations, we have developed a new and powerful deep learning segmentation method. Our method exploits new deep attentive modules with mixed kernel convolutions within a fully convolutional neural network architecture that utilizes deep supervision and residual connections. We evaluated our method quantitatively based on several performance measures and expert evaluations. Results show that our method outperforms several state-of-the-art deep models for segmentation, as well as a state-of-the-art multi-atlas segmentation technique. We achieved average Dice similarity coefficient of 0.87, average Hausdorff distance of 0.96 mm, and average symmetric surface difference of 0.28 mm on reconstructed fetal brain MRI scans of fetuses scanned in the gestational age range of 16 to 39 weeks (28.6± 5.3). With a computation time of less than 1 minute per fetal brain, our method can facilitate and accelerate large-scale studies on normal and altered fetal brain cortical maturation and folding. Haoran Dou, Davood Karimi, Caitlin K. Rollins, Cynthia M. Ortinau, Lana Vasung, Clemente Velasco-Annis, Abdelhakim Ouaalam, Xin Yang 0009, Dong Ni 0001, Ali Gholipour |
IEEE Trans. Medical Imaging | 8 |
| 2021 | Agent With Warm Start and Adaptive Dynamic Termination for Plane Localization in 3D UltrasoundabstractAccurate standard plane (SP) localization is the fundamental step for prenatal ultrasound (US) diagnosis. Typically, dozens of US SPs are collected to determine the clinical diagnosis. 2D US has to perform scanning for each SP, which is time-consuming and operator-dependent. While 3D US containing multiple SPs in one shot has the inherent advantages of less user-dependency and more efficiency. Automatically locating SP in 3D US is very challenging due to the huge search space and large fetal posture variations. Our previous study proposed a deep reinforcement learning (RL) framework with an alignment module and active termination to localize SPs in 3D US automatically. However, termination of agent search in RL is important and affects the practical deployment. In this study, we enhance our previous RL framework with a newly designed adaptive dynamic termination to enable an early stop for the agent searching, saving at most 67% inference time, thus boosting the accuracy and efficiency of the RL framework at the same time. Besides, we validate the effectiveness and generalizability of our algorithm extensively on our in-house multi-organ datasets containing 433 fetal brain volumes, 519 fetal abdomen volumes, and 683 uterus volumes. Our approach achieves localization error of 2.52mm/10.26°, 2.48mm/10.39°, 2.02mm/10.48°, 2.00mm/14.57°, 2.61mm/9.71°, 3.09mm/9.58°, 1.49mm/7.54°for the transcerebellar, transventricular, transthalamic planes in fetal brain, abdominal plane in fetal abdomen, and mid-sagittal, transverse and coronal planes in uterus, respectively. Experimental results show that our method is general and has the potential to improve the efficiency and standardization of US scanning. Xin Yang 0009, Haoran Dou, Ruobing Huang, Wufeng Xue, Yuhao Huang 0001, Jikuan Qian, Yuanji Zhang, Huanjia Luo, Huizhi Guo, Tianfu Wang 0001, Yi Xiong 0001, Dong Ni 0001 |
IEEE Trans. Medical Imaging | 1 |
| 2020 | Searching Collaborative Agents for Multi-plane Localization in 3D Ultrasound
Yuhao Huang 0001, Xin Yang 0009, Rui Li 0038, Jikuan Qian, Xiaoqiong Huang, Wenlong Shi, Haoran Dou, Chaoyu Chen, Yuanji Zhang, Huanjia Luo, Alejandro F. Frangi, Yi Xiong 0001, Dong Ni 0001 |
MICCAI (3) | 2 |
| 2020 | Contrastive Rendering for Ultrasound Image Segmentation
Haoming Li 0008, Xin Yang 0009, Jiamin Liang, Wenlong Shi, Chaoyu Chen, Haoran Dou, Rui Li 0038, Guangquan Zhou, Jinghui Fang, Xiaowen Liang, Ruobing Huang, Alejandro F. Frangi, Dong Ni 0001 |
MICCAI (3) | 2 |
| 2020 | Auto-weighting for Breast Cancer Classification in Multimodal Ultrasound
Jian Wang 0099, Juzheng Miao, Xin Yang 0009, Rui Li 0038, Guangquan Zhou, Yuhao Huang 0001, Wufeng Xue, Xiaohong Jia 0003, Jianqiao Zhou, Ruobing Huang, Dong Ni 0001 |
MICCAI (6) | 3 |
| 2020 | Computer-Aided Tumor Diagnosis in Automated Breast Ultrasound Using 3D Detection Network
Junxiong Yu, Chaoyu Chen, Xin Yang 0009, Yi Wang 0031, Dan Yan, Jianxing Zhang, Dong Ni 0001 |
MICCAI (6) | 3 |
| 2020 | Uncertainty-aware domain alignment for anatomical structure segmentation
Cheng Bian, Chenglang Yuan, Jiexiang Wang, Meng Li 0090, Xin Yang 0009, Kai Ma 0002, Yefeng Zheng 0001 |
Medical Image Anal. | 5 |
| 2020 | CR-Unet: A Composite Network for Ovary and Follicle Segmentation in Ultrasound ImagesabstractTransvaginal ultrasound (TVUS) is widely used in infertility treatment. The size and shape of the ovary and follicles must be measured manually for assessing their physiological status by sonographers. However, this process is extremely time-consuming and operator-dependent. In this study, we propose a novel composite network, namely CR-Unet, to simultaneously segment the ovary and follicles in TVUS. The CR-Unet incorporates the spatial recurrent neural network (RNN) into a plain U-Net. It can effectively learn multi-scale and long-range spatial contexts to combat the challenges of this task, such as the poor image quality, low contrast, boundary ambiguity, and complex anatomy shapes. We further adopt deep supervision strategy to make model training more effective and efficient. In addition, self-supervision is employed to iteratively refine the segmentation results. Experiments on 3204 TVUS images from 219 patients demonstrate the proposed method achieved the best segmentation performance compared to other state-of-the-art methods for both the ovary and follicles, with a Dice Similarity Coefficient (DSC) of 0.912 and 0.858, respectively. Haoming Li 0008, Jinghui Fang, Shengfeng Liu, Xiaowen Liang, Xin Yang 0009, Zixin Mai, Manh The Van, Tianfu Wang 0001, Dong Ni 0001 |
IEEE J. Biomed. Health Informatics | 5 |
| 2020 | Deeply-Supervised Networks With Threshold Loss for Cancer Detection in Automated Breast UltrasoundabstractABUS, or Automated breast ultrasound, is an innovative and promising method of screening for breast examination. Comparing to common B-mode 2D ultrasound, ABUS attains operator-independent image acquisition and also provides 3D views of the whole breast. Nonetheless, reviewing ABUS images is particularly time-intensive and errors by oversight might occur. For this study, we offer an innovative 3D convolutional network, which is used for ABUS for automated cancer detection, in order to accelerate reviewing and meanwhile to obtain high detection sensitivity with low false positives (FPs). Specifically, we offer a densely deep supervision method in order to augment the detection sensitivity greatly by effectively using multi-layer features. Furthermore, we suggest a threshold loss in order to present voxel-level adaptive threshold for discerning cancer vs. non-cancer, which can attain high sensitivity with low false positives. The efficacy of our network is verified from a collected dataset of 219 patients with 614 ABUS volumes, including 745 cancer regions, and 144 healthy women with a total of 900 volumes, without abnormal findings. Extensive experiments demonstrate our method attains a sensitivity of 95% with 0.84 FP per volume. The proposed network provides an effective cancer detection scheme for breast examination using ABUS by sustaining high sensitivity with low false positives. The code is publicly available at https://github.com/nawang0226/abus_code. Yi Wang 0031, Junxiong Yu, Chenchen Qin, Xin Yang 0009, Tianfu Wang 0001, Anhua Li, Dong Ni 0001 |
IEEE Trans. Medical Imaging | 7 |
| 2020 | DoFE: Domain-Oriented Feature Embedding for Generalizable Fundus Image Segmentation on Unseen DatasetsabstractDeep convolutional neural networks have significantly boosted the performance of fundus image segmentation when test datasets have the same distribution as the training datasets. However, in clinical practice, medical images often exhibit variations in appearance for various reasons, e.g., different scanner vendors and image quality. These distribution discrepancies could lead the deep networks to over-fit on the training datasets and lack generalization ability on the unseen test datasets. To alleviate this issue, we present a novel Domain-oriented Feature Embedding (DoFE) framework to improve the generalization ability of CNNs on unseen target domains by exploring the knowledge from multiple source domains. Our DoFE framework dynamically enriches the image features with additional domain prior knowledge learned from multi-source domains to make the semantic features more discriminative. Specifically, we introduce a Domain Knowledge Pool to learn and memorize the prior information extracted from multi-source domains. Then the original image features are augmented with domain-oriented aggregated features, which are induced from the knowledge pool based on the similarity between the input image and multi-source domain images. We further design a novel domain code prediction branch to infer this similarity and employ an attention-guided mechanism to dynamically combine the aggregated features with the semantic features. We comprehensively evaluate our DoFE framework on two fundus image segmentation tasks, including the optic cup and disc segmentation and vessel segmentation. Our DoFE framework generates satisfying segmentation results on unseen datasets and surpasses other domain generalization and network regularization methods. Lequan Yu, Kang Li 0007, Xin Yang 0009, Chi-Wing Fu, Pheng-Ann Heng |
IEEE Trans. Medical Imaging | 4 |
| 2019 | FetusMap: Fetal Pose Estimation in 3D Ultrasound
Xin Yang 0009, Wenlong Shi, Haoran Dou, Jikuan Qian, Yi Wang 0031, Wufeng Xue, Shengli Li 0001, Dong Ni 0001, Pheng-Ann Heng |
MICCAI (5) | 1 |
| 2019 | Agent with Warm Start and Active Termination for Plane Localization in 3D Ultrasound
Haoran Dou, Xin Yang 0009, Jikuan Qian, Wufeng Xue, Xu Wang 0017, Lequan Yu, Yi Xiong 0001, Pheng-Ann Heng, Dong Ni 0001 |
MICCAI (5) | 2 |
| 2019 | Boundary and Entropy-Driven Adversarial Learning for Fundus Image Segmentation
Lequan Yu, Kang Li 0007, Xin Yang 0009, Chi-Wing Fu, Pheng-Ann Heng |
MICCAI (1) | 4 |
| 2019 | Evaluation of algorithms for Multi-Modality Whole Heart Segmentation: An open-access grand challengeabstractKnowledge of whole heart anatomy is a prerequisite for many clinical applications. Whole heart segmentation (WHS), which delineates substructures of the heart, can be very valuable for modeling and analysis of the anatomy and functions of the heart. However, automating this segmentation can be challenging due to the large variation of the heart shape, and different image qualities of the clinical data. To achieve this goal, an initial set of training data is generally needed for constructing priors or for training. Furthermore, it is difficult to perform comparisons between different methods, largely due to differences in the datasets and evaluation metrics used. This manuscript presents the methodologies and evaluation results for the WHS algorithms selected from the submissions to the Multi-Modality Whole Heart Segmentation (MM-WHS) challenge, in conjunction with MICCAI 2017. The challenge provided 120 three-dimensional cardiac images covering the whole heart, including 60 CT and 60 MRI volumes, all acquired in clinical environments with manual delineation. Ten algorithms for CT data and eleven algorithms for MRI data, submitted from twelve groups, have been evaluated. The results showed that the performance of CT WHS was generally better than that of MRI WHS. The segmentation of the substructures for different categories of patients could present different levels of challenge due to the difference in imaging and variations of heart shapes. The deep learning (DL)-based methods demonstrated great potential, though several of them reported poor results in the blinded evaluation. Their performance could vary greatly across different network structures and training strategies. The conventional algorithms, mainly based on multi-atlas segmentation, demonstrated good performance, though the accuracy and computational efficiency could be limited. The challenge, including provision of the annotated training data and the blinded evaluation for submitted algorithms on the test data, continues as an ongoing benchmarking resource via its homepage (www.sdspeople.fudan.edu.cn/zhuangxiahai/0/mmwhs/). Xiahai Zhuang, Lei Li 0020, Christian Payer, Darko Stern, Martin Urschler, Mattias P. Heinrich, Julien Oster, Chunliang Wang, Örjan Smedby, Cheng Bian, Xin Yang 0009, Pheng-Ann Heng, Aliasghar Mortazi, Ulas Bagci, Guanyu Yang 0001, Chenchen Sun, Gaetan Galisot, Jean-Yves Ramel, Guang Yang 0006 |
Medical Image Anal. | 11 |
| 2019 | Deep Attentive Features for Prostate Segmentation in 3D Transrectal UltrasoundabstractAutomatic prostate segmentation in transrectal ultrasound (TRUS) images is of essential importance for image-guided prostate interventions and treatment planning. However, developing such automatic solutions remains very challenging due to the missing/ambiguous boundary and inhomogeneous intensity distribution of the prostate in TRUS, as well as the large variability in prostate shapes. This paper develops a novel 3D deep neural network equipped with attention modules for better prostate segmentation in TRUS by fully exploiting the complementary information encoded in different layers of the convolutional neural network (CNN). Our attention module utilizes the attention mechanism to selectively leverage the multi-level features integrated from different layers to refine the features at each individual layer, suppressing the non-prostate noise at shallow layers of the CNN and increasing more prostate details into features at deep layers. Experimental results on challenging 3D TRUS volumes show that our method attains satisfactory segmentation performance. The proposed attention mechanism is a general strategy to aggregate multi-level deep features and has the potential to be used for other medical image segmentation tasks. The code is publicly available at https://github.com/wulalago/DAF3D. Yi Wang 0031, Dong Ni 0001, Haoran Dou, Xiaowei Hu 0001, Lei Zhu 0003, Xin Yang 0009, Harry Qin, Pheng-Ann Heng, Tianfu Wang 0001 |
IEEE Trans. Medical Imaging | 6 |
| 2019 | Patch-Based Output Space Adversarial Learning for Joint Optic Disc and Cup SegmentationabstractGlaucoma is a leading cause of irreversible blindness. Accurate segmentation of the optic disc (OD) and optic cup (OC) from fundus images is beneficial to glaucoma screening and diagnosis. Recently, convolutional neural networks demonstrate promising progress in the joint OD and OC segmentation. However, affected by the domain shift among different datasets, deep networks are severely hindered in generalizing across different scanners and institutions. In this paper, we present a novel patch-based output space adversarial learning framework ( p OSAL) to jointly and robustly segment the OD and OC from different fundus image datasets. We first devise a lightweight and efficient segmentation network as a backbone. Considering the specific morphology of OD and OC, a novel morphology-aware segmentation loss is proposed to guide the network to generate accurate and smooth segmentation. Our p OSAL framework then exploits unsupervised domain adaptation to address the domain shift challenge by encouraging the segmentation in the target domain to be similar to the source ones. Since the whole-segmentation-based adversarial loss is insufficient to drive the network to capture segmentation details, we further design the p OSAL in a patch-based fashion to enable fine-grained discrimination on local segmentation details. We extensively evaluate our p OSAL framework and demonstrate its effectiveness in improving the segmentation performance on three public retinal fundus image datasets, i.e., Drishti-GS, RIM-ONE-r3, and REFUGE. Furthermore, our p OSAL framework achieved the first place in the OD and OC segmentation tasks in the MICCAI 2018 Retinal Fundus Glaucoma Challenge. Lequan Yu, Xin Yang 0009, Chi-Wing Fu, Pheng-Ann Heng |
IEEE Trans. Medical Imaging | 3 |
| 2019 | Towards Automated Semantic Segmentation in Prenatal Volumetric UltrasoundabstractVolumetric ultrasound is rapidly emerging as a viable imaging modality for routine prenatal examinations. Biometrics obtained from the volumetric segmentation shed light on the reformation of precise maternal and fetal health monitoring. However, the poor image quality, low contrast, boundary ambiguity, and complex anatomy shapes conspire toward a great lack of efficient tools for the segmentation. It makes 3-D ultrasound difficult to interpret and hinders the widespread of 3-D ultrasound in obstetrics. In this paper, we are looking at the problem of semantic segmentation in prenatal ultrasound volumes. Our contribution is threefold: 1) we propose the first and fully automatic framework to simultaneously segment multiple anatomical structures with intensive clinical interest, including fetus, gestational sac, and placenta, which remains a rarely studied and arduous challenge; 2) we propose a composite architecture for dense labeling, in which a customized 3-D fully convolutional network explores spatial intensity concurrency for initial labeling, while a multi-directional recurrent neural network (RNN) encodes spatial sequentiality to combat boundary ambiguity for significant refinement; and 3) we introduce a hierarchical deep supervision mechanism to boost the information flow within RNN and fit the latent sequence hierarchy in fine scales, and further improve the segmentation results. Extensively verified on in-house large data sets, our method illustrates a superior segmentation performance, decent agreements with expert measurements and high reproducibilities against scanning variations, and thus is promising in advancing the prenatal ultrasound examinations. Xin Yang 0009, Lequan Yu, Shengli Li 0001, Huaxuan Wen, Dandan Luo, Cheng Bian, Harry Qin, Dong Ni 0001, Pheng-Ann Heng |
IEEE Trans. Medical Imaging | 1 |
| 2018 | Densely Deep Supervised Networks with Threshold Loss for Cancer Detection in Automated Breast Ultrasound
Cheng Bian, Yi Wang 0031, Chenchen Qin, Xin Yang 0009, Tianfu Wang 0001, Anhua Li, Dinggang Shen, Dong Ni 0001 |
MICCAI (4) | 6 |
| 2018 | Deep Attentional Features for Prostate Segmentation in Ultrasound
Yi Wang 0031, Zijun Deng, Xiaowei Hu 0001, Lei Zhu 0003, Xin Yang 0009, Xuemiao Xu, Pheng-Ann Heng, Dong Ni 0001 |
MICCAI (4) | 5 |
| 2018 | Generalizing Deep Models for Ultrasound Image Segmentation
Xin Yang 0009, Haoran Dou, Xu Wang 0017, Cheng Bian, Shengli Li 0001, Dong Ni 0001, Pheng-Ann Heng |
MICCAI (4) | 1 |
| 2018 | Deep Learning Techniques for Automatic MRI Cardiac Multi-Structures Segmentation and Diagnosis: Is the Problem Solved?abstractDelineation of the left ventricular cavity, myocardium, and right ventricle from cardiac magnetic resonance images (multi-slice 2-D cine MRI) is a common clinical task to establish diagnosis. The automation of the corresponding tasks has thus been the subject of intense research over the past decades. In this paper, we introduce the "Automatic Cardiac Diagnosis Challenge" dataset (ACDC), the largest publicly available and fully annotated dataset for the purpose of cardiac MRI (CMR) assessment. The dataset contains data from 150 multi-equipments CMRI recordings with reference measurements and classification from two medical experts. The overarching objective of this paper is to measure how far state-of-the-art deep learning methods can go at assessing CMRI, i.e., segmenting the myocardium and the two ventricles as well as classifying pathologies. In the wake of the 2017 MICCAI-ACDC challenge, we report results from deep learning methods provided by nine research groups for the segmentation task and four groups for the classification task. Results show that the best methods faithfully reproduce the expert analysis, leading to a mean value of 0.97 correlation score for the automatic extraction of clinical indices and an accuracy of 0.96 for automatic diagnosis. These results clearly open the door to highly accurate and fully automatic analysis of cardiac CMRI. We also identify scenarios for which deep learning methods are still failing. Both the dataset and detailed results are publicly available online, while the platform will remain open for new submissions. Olivier Bernard 0001, Alain Lalande, Clément Zotti, Frederic Cervenansky, Xin Yang 0009, Pheng-Ann Heng, Irem Cetin, Karim Lekadir, Oscar Camara 0001, Miguel Ángel González Ballester, Gerard Sanroma, Sandy Napel, Steffen E. Petersen, Georgios Tziritas, Ilias Grinias, Mahendra Khened, Alex Varghese, Ganapathy Krishnamurthi, Marc-Michel Rohé, Xavier Pennec, Maxime Sermesant, Fabian Isensee, Paul F. Jaeger, Klaus H. Maier-Hein, Peter M. Full, Ivo Wolf, Sandy Engelhardt, Christian F. Baumgartner, Lisa M. Koch, Jelmer M. Wolterink, Ivana Isgum, Yeonggul Jang, Yoonmi Hong, Jay Patravali, Shubham Jain 0006, Olivier Humbert, Pierre-Marc Jodoin |
IEEE Trans. Medical Imaging | 5 |
| 2017 | Fine-Grained Recurrent Neural Networks for Automatic Prostate Segmentation in Ultrasound ImagesabstractBoundary incompleteness raises great challenges to automatic prostate segmentation in ultrasound images. Shape prior can provide strong guidance in estimating the missing boundary, but traditional shape models often suffer from hand-crafted descriptors and local information loss in the fitting procedure. In this paper, we attempt to address those issues with a novel framework. The proposed framework can seamlessly integrate feature extraction and shape prior exploring, and estimate the complete boundary with a sequential manner. Our framework is composed of three key modules. Firstly, we serialize the static 2D prostate ultrasound images into dynamic sequences and then predict prostate shapes by sequentially exploring shape priors. Intuitively, we propose to learn the shape prior with the biologically plausible Recurrent Neural Networks (RNNs). This module is corroborated to be effective in dealing with the boundary incompleteness. Secondly, to alleviate the bias caused by different serialization manners, we propose a multi-view fusion strategy to merge shape predictions obtained from different perspectives. Thirdly, we further implant the RNN core into a multiscale Auto-Context scheme to successively refine the details of the shape prediction map. With extensive validation on challenging prostate ultrasound images, our framework bridges severe boundary incompleteness and achieves the best performance in prostate boundary delineation when compared with several advanced methods. Additionally, our approach is general and can be extended to other medical image segmentation tasks, where boundary incompleteness is one of the main challenges. Xin Yang 0009, Lequan Yu, Lingyun Wu, Yi Wang 0031, Dong Ni 0001, Harry Qin, Pheng-Ann Heng |
AAAI | 1 |
| 2017 | Volumetric ConvNets with Mixed Residual Connections for Automated Prostate Segmentation from 3D MR ImagesabstractAutomated prostate segmentation from 3D MR images is very challenging due to large variations of prostate shape and indistinct prostate boundaries. We propose a novel volumetric convolutional neural network (ConvNet) with mixed residual connections to cope with this challenging problem. Compared with previous methods, our volumetric ConvNet has two compelling advantages. First, it is implemented in a 3D manner and can fully exploit the 3D spatial contextual information of input data to perform efficient, precise and volume-to-volume prediction. Second and more important, the novel combination of residual connections (i.e., long and short) can greatly improve the training efficiency and discriminative capability of our network by enhancing the information propagation within the ConvNet both locally and globally. While the forward propagation of location information can improve the segmentation accuracy, the smooth backward propagation of gradient flow can accelerate the convergence speed and enhance the discrimination capability. Extensive experiments on the open MICCAI PROMISE12 challenge dataset corroborated the effectiveness of the proposed volumetric ConvNet with mixed residual connections. Our method ranked the first in the challenge, outperforming other competitors by a large margin with respect to most of evaluation metrics. The proposed volumetric ConvNet is general enough and can be easily extended to other medical image analysis tasks, especially ones with limited training data. Lequan Yu, Xin Yang 0009, Hao Chen 0011, Harry Qin, Pheng-Ann Heng |
AAAI | 2 |
| 2017 | Towards Automatic Semantic Segmentation in Volumetric Ultrasound
Xin Yang 0009, Lequan Yu, Shengli Li 0001, Xu Wang 0017, Harry Qin, Dong Ni 0001, Pheng-Ann Heng |
MICCAI (1) | 1 |
| 2017 | Automatic 3D Cardiovascular MR Segmentation with Densely-Connected Volumetric ConvNets
Lequan Yu, Jie-Zhi Cheng, Qi Dou 0001, Xin Yang 0009, Hao Chen 0011, Harry Qin, Pheng-Ann Heng |
MICCAI (2) | 4 |
| 2017 | 3D deeply supervised network for automated segmentation of volumetric medical images
Qi Dou 0001, Lequan Yu, Hao Chen 0011, Yueming Jin, Xin Yang 0009, Harry Qin, Pheng-Ann Heng |
Medical Image Anal. | 5 |
| 2015 | Locally-constrained boundary regression for segmentation of prostate and rectum in the planning CT images
Yeqin Shao, Yaozong Gao, Qian Wang 0001, Xin Yang 0009, Dinggang Shen |
Medical Image Anal. | 4 |
| 2015 | Standard Plane Localization in Fetal Ultrasound via Domain Transferred Deep Neural NetworksabstractAutomatic localization of the standard plane containing complicated anatomical structures in ultrasound (US) videos remains a challenging problem. In this paper, we present a learning-based approach to locate the fetal abdominal standard plane (FASP) in US videos by constructing a domain transferred deep convolutional neural network (CNN). Compared with previous works based on low-level features, our approach is able to represent the complicated appearance of the FASP and hence achieve better classification performance. More importantly, in order to reduce the overfitting problem caused by the small amount of training samples, we propose a transfer learning strategy, which transfers the knowledge in the low layers of a base CNN trained from a large database of natural images to our task-specific CNN. Extensive experiments demonstrate that our approach outperforms the state-of-the-art method for the FASP localization as well as the CNN only trained on the limited US training samples. The proposed approach can be easily extended to other similar medical image computing problems, which often suffer from the insufficient training samples when exploiting the deep CNN to represent high-level features. Hao Chen 0011, Dong Ni 0001, Harry Qin, Shengli Li 0001, Xin Yang 0009, Tianfu Wang 0001, Pheng-Ann Heng |
IEEE J. Biomed. Health Informatics | 5 |
| 2014 | Using Social Media Platforms for Human-Robot Interaction in Domestic EnvironmentabstractThis article explores the application of existing social media platforms for human–robot interaction. With the increasing popularity of social media platforms that connect humans, we propose to portray domestic robots as buddies on the contact list of family members and present a robot management system that employs complementary social media platforms for humans to interact with the vacuuming robot Roomba and a surveillance robot developed on top of iRobot Create. The social media platforms adopted include short message services (SMS), instant messenger (MSN), an online shared calendar (Google Calendar), and a social networking site (Facebook). Hence, we can provide a rich set of user-familiar, intuitive, and highly accessible interfaces, allowing users to flexibly choose their preferred tools in different situations. An in-lab experiment and a multiday field study are conducted to study the characteristics and strengths of each interface and to investigate users’ perception to the robots and behaviors in choosing the interfaces. Xiaoning Ma, Xin Yang 0009, Shengdong Zhao 0001, Chi-Wing Fu, Ziquan Lan, Yiming Pu |
Int. J. Hum. Comput. Interact. | 2 |
| 2014 | Hierarchical Lung Field Segmentation With Joint Shape and Appearance Sparse LearningabstractLung field segmentation in the posterior-anterior (PA) chest radiograph is important for pulmonary disease diagnosis and hemodialysis treatment. Due to high shape variation and boundary ambiguity, accurate lung field segmentation from chest radiograph is still a challenging task. To tackle these challenges, we propose a joint shape and appearance sparse learning method for robust and accurate lung field segmentation. The main contributions of this paper are: 1) a robust shape initialization method is designed to achieve an initial shape that is close to the lung boundary under segmentation; 2) a set of local sparse shape composition models are built based on local lung shape segments to overcome the high shape variations; 3) a set of local appearance models are similarly adopted by using sparse representation to capture the appearance characteristics in local lung boundary segments, thus effectively dealing with the lung boundary ambiguity; 4) a hierarchical deformable segmentation framework is proposed to integrate the scale-dependent shape and appearance information together for robust and accurate segmentation. Our method is evaluated on 247 PA chest radiographs in a public dataset. The experimental results show that the proposed local shape and appearance models outperform the conventional shape and appearance models. Compared with most of the state-of-the-art lung field segmentation methods under comparison, our method also shows a higher accuracy, which is comparable to the inter-observer annotation variation. Yeqin Shao, Yaozong Gao, Yanrong Guo, Yonghong Shi, Xin Yang 0009, Dinggang Shen |
IEEE Trans. Medical Imaging | 5 |