Six low-cost air quality sensors were installed on the front roof area of three buses to enable real-time monitoring of air quality across the city of Valladolid (Spain) over a 7-month period, capturing variability in meteorological conditions and emission sources. Prior to deployment, the sensors were placed at a reference station in Barcelona (Spain) for validation and calibration. Measurements deviating by more than 30% from reference values were discarded, and correlation coefficients (R²) were calculated. After the monitoring campaign, the calibration procedure was repeated. The results (R2= 0.85) suggest that bus-mounted sensors can effectively support real-time detection of urban air quality changes and contribute to detailed air quality mapping. Integrating data from reference air quality monitoring networks (AQMNs) with low-cost sensor (LCS) systems can strengthen evidence-based policymaking and help refine regulatory frameworks aimed at reducing urban air pollution.

[This corrects the article DOI: 10.1371/journal.pcbi.1011921.].

In an ever-changing visual world, animals' survival depends on their ability to perceive and respond to rapidly changing motion cues. The primary visual cortex (V1) is at the forefront of this sensory processing, orchestrating neural responses to perturbations in visual flow. However, the underlying neural mechanisms that lead to distinct cortical responses to such perturbations remain enigmatic. In this study, our objective was to uncover the neural dynamics that govern V1 neurons' responses to visual flow perturbations using a biologically realistic computational model. By subjecting the model to sudden changes in visual input, we observed opposing cortical responses in excitatory layer 2/3 (L2/3) neurons, namely, depolarizing and hyperpolarizing responses. We found that this segregation was primarily driven by the competition between external visual input and recurrent inhibition, particularly within L2/3 and L4. This division was not observed in excitatory L5/6 neurons, suggesting a more prominent role for inhibitory mechanisms in the visual processing of the upper cortical layers. Our findings share similarities with recent experimental studies focusing on the opposing influence of top-down and bottom-up inputs in the mouse primary visual cortex during visual flow perturbations.

Assessing the impact of mobility on epidemic spreading is of crucial importance for understanding the effect of policies like mass quarantines and selective re-openings. While many factors affect disease incidence at a local level, making it more or less homogeneous with respect to other areas, the importance of multi-seeding has often been overlooked. Multi-seeding occurs when several independent (non-clustered) infected individuals arrive at a susceptible population. This can lead to independent outbreaks that spark from distinct areas of the local contact (social) network. Such mechanism has the potential to boost incidence, making control efforts and contact tracing less effective. Here, through a modeling approach we show that the effect produced by the number of initial infections is non-linear on the incidence peak and peak time. When case importations are carried by mobility from an already infected area, this effect is further enhanced by the local demography and underlying mixing patterns: the impact of every seed is larger in smaller populations. Finally, both in the model simulations and the analysis, we show that a multi-seeding effect combined with mobility restrictions can explain the observed spatial heterogeneities in the first wave of COVID-19 incidence and mortality in five European countries. Our results allow us for identifying what we have called epidemic epicenter: an area that shapes incidence and mortality peaks in the entire country. The present work further clarifies the nonlinear effects that mobility can have on the evolution of an epidemic and highlight their relevance for epidemic control.

Micro-blogging systems such as Twitter expose digital traces of social discourse with an unprecedented degree of resolution of individual behaviors. They offer an opportunity to investigate how a large-scale social system responds to exogenous or endogenous stimuli, and to disentangle the temporal, spatial and topical aspects of users' activity. Here we focus on spikes of collective attention in Twitter, and specifically on peaks in the popularity of hashtags. Users employ hashtags as a form of social annotation, to define a shared context for a specific event, topic, or meme. We analyze a large-scale record of Twitter activity and find that the evolution of hashtag popularity over time defines discrete classes of hashtags. We link these dynamical classes to the events the hashtags represent and use text mining techniques to provide a semantic characterization of the hashtag classes. Moreover, we track the propagation of hashtags in the Twitter social network and find that epidemic spreading plays a minor role in hashtag popularity, which is mostly driven by exogenous factors.