We consider Online Convex Optimization (OCO) in the setting where the costs are $m$-strongly convex and the online learner pays a switching cost for changing decisions between rounds. We show that the recently proposed Online Balanced Descent (OBD) algorithm is constant competitive in this setting, with competitive ratio $3 + O(1/m)$, irrespective of the ambient dimension. Additionally, we show that when the sequence of cost functions is $\epsilon$-smooth, OBD has near-optimal dynamic regret and maintains strong per-round accuracy. We demonstrate the generality of our approach by showing that the OBD framework can be used to construct competitive algorithms for a variety of online problems across learning and control, including online variants of ridge regression, logistic regression, maximum likelihood estimation, and LQR control.

We study online convex optimization in a setting where the learner seeks to minimize the sum of a per-round hitting cost and a movement cost which is incurred when changing decisions between rounds. We prove a new lower bound on the competitive ratio of any online algorithm in the setting where the costs are $m$-strongly convex and the movement costs are the squared $\ell_2$ norm. This lower bound shows that no algorithm can achieve a competitive ratio that is $o(m^{-1/2})$ as $m$ tends to zero. No existing algorithms have competitive ratios matching this bound, and we show that the state-of-the-art algorithm, Online Balanced Decent (OBD), has a competitive ratio that is $\Omega(m^{-2/3})$. We additionally propose two new algorithms, Greedy OBD (G-OBD) and Regularized OBD (R-OBD) and prove that both algorithms have an $O(m^{-1/2})$ competitive ratio. The result for G-OBD holds when the hitting costs are quasiconvex and the movement costs are the squared $\ell_2$ norm, while the result for R-OBD holds when the hitting costs are $m$-strongly convex and the movement costs are Bregman Divergences. Further, we show that R-OBD simultaneously achieves constant, dimension-free competitive ratio and sublinear regret when hitting costs are strongly convex.

We study \emph{smoothed online convex optimization}, a version of online convex optimization where the learner incurs a penalty for changing her actions between rounds. Given a $\Omega(\sqrt{d})$ lower bound on the competitive ratio of any online algorithm, where $d$ is the dimension of the action space, we ask under what conditions this bound can be beaten. We introduce a novel algorithmic framework for this problem, Online Balanced Descent (OBD), which works by iteratively projecting the previous point onto a carefully chosen level set of the current cost function so as to balance the switching costs and hitting costs. We demonstrate the generality of the OBD framework by showing how, with different choices of “balance,” OBD can improve upon state-of-the-art performance guarantees for both competitive ratio and regret; in particular, OBD is the first algorithm to achieve a dimension-free competitive ratio, $3 + O(1/\alpha)$, for locally polyhedral costs, where $\alpha$ measures the “steepness” of the costs. We also prove bounds on the dynamic regret of OBD when the balance is performed in the dual space that are dimension-free and imply that OBD has sublinear static regret.

MOTIVATION: At the center of computational systems biology are mathematical models that capture the dynamics of biological systems and offer novel insights. The bottleneck in the construction of these models is presently the identification of model parameters that make the model consistent with observed data. Dynamic flux estimation (DFE) is a novel methodological framework for estimating parameters for models of metabolic systems from time-series data. DFE consists of two distinct phases, an entirely model-free and assumption-free data analysis and a model-based mathematical characterization of process representations. The model-free phase reveals inconsistencies within the data, and between data and the alleged system topology, while the model-based phase allows quantitative diagnostics of whether--or to what degree--the assumed mathematical formulations are appropriate or in need of improvement. Hallmarks of DFE are the facility to: diagnose data and model consistency; circumvent undue compensation of errors; determine functional representations of fluxes uncontaminated by errors in other fluxes and pinpoint sources of remaining errors. Our results suggest that the proposed approach is more effective and robust than presently available methods for deriving metabolic models from time-series data. Its avoidance of error compensation among process descriptions promises significantly improved extrapolability toward new data or experimental conditions.