Brain tumor segmentation (BTS) in magnetic resonance image (MRI) is crucial for brain tumor diagnosis, cancer management and research purposes. With the great success of the ten-year BraTS challenges as well as the advances of CNN and Transformer algorithms, a lot of outstanding BTS models have been proposed to tackle the difficulties of BTS in different technical aspects. However, existing studies hardly consider how to fuse the multi-modality images in a reasonable manner. In this paper, we leverage the clinical knowledge of how radiologists diagnose brain tumors from multiple MRI modalities and propose a clinical knowledge-driven brain tumor segmentation model, called CKD-TransBTS. Instead of directly concatenating all the modalities, we re-organize the input modalities by separating them into two groups according to the imaging principle of MRI. A dual-branch hybrid encoder with the proposed modality-correlated cross-attention block (MCCA) is designed to extract the multi-modality image features. The proposed model inherits the strengths from both Transformer and CNN with the local feature representation ability for precise lesion boundaries and long-range feature extraction for 3D volumetric images. To bridge the gap between Transformer and CNN features, we propose a Trans&CNN Feature Calibration block (TCFC) in the decoder. We compare the proposed model with six CNN-based models and six transformer-based models on the BraTS 2021 challenge dataset. Extensive experiments demonstrate that the proposed model achieves state-of-the-art brain tumor segmentation performance compared with all the competitors.

In this paper, we propose a deep propagation based image matting framework by introducing deep learning into learning an alpha matte propagation principal. Our deep learning architecture is a concatenation of a deep feature extraction module, an affinity learning module and a matte propagation module. These three modules are all differentiable and can be optimized jointly via an end-to-end training process. Our framework results in a semantic-level pairwise similarity of pixels for propagation by learning deep image representations adapted to matte propagation. It combines the power of deep learning and matte propagation and can therefore surpass prior state-of-the-art matting techniques in terms of both accuracy and training complexity, as validated by our experimental results from 243K images created based on two benchmark matting databases.