Real life data can often be modeled as graphs, in which nodes represent objects and edges between nodes indicate their relationships. Large graph datasets are common in many emerging applications. Examples span from social networks, biological networks to computer networks. To fully exploit the wealth of information encoded in graphs, systems for managing and analyzing graph data are critical. To address this need, we have designed and developed a graph querying toolkit, called Periscope/GQ. This toolkit is built on top of a traditional RDBMS. It provides a uniform schema for storing graphs in the database and supports various graph query operations, especially sophisticated operations, such as approximate graph matching, large graph alignment and graph summarization. Users can easily combine several operations to perform complex analysis on graphs. In addition, Periscope/GQ employs several novel indexing techniques to speed up query execution. This demonstration will highlight the use of Periscope/GQ in two application domains: life science and social networking.