Consider two parties, Alice and Bob, who hold private inputs x and y, and wish to compute a function f (x, y) privately in the information theoretic sense; that is, each party should learn nothing beyond f (x, y). However, the communication channel available to them is noisy. This means that the channel can introduce errors in the transmission between the two parties. Moreover, the channel is adversarial in the sense that it knows the protocol that Alice and Bob are running, and maliciously introduces errors to disrupt the communication, subject to some bound on the total number of errors. A fundamental question in this setting is to design a protocol that remains private in the presence of large number of errors. If Alice and Bob are only interested in computing f (x, y) correctly, and not privately, then quite robust protocols are known that can tolerate a constant fraction of errors. However, none of these solutions is applicable in the setting of privacy, as they inherently leak information about the parties' inputs. This leads to the question whether we can simultaneously achieve privacy and error-resilience against a constant fraction of errors. We show that privacy and errorresilience are contradictory goals. In particular, we show that for every constant c > 0, there exists a function f which is privately computable in the error-less setting, but for which no private and correct protocol is resilient against a c-fraction of errors.

Consider two parties Alice and Bob, who hold private inputs x and y, and wish to compute a function f(x, y) privately in the information theoretic sense; that is, each party should learn nothing beyond f(x, y). However, the communication channel available to them is noisy. This means that the channel can introduce errors in the transmission between the two parties. Moreover, the channel is adversarial in the sense that it knows the protocol that Alice and Bob are running, and maliciously introduces errors to disrupt the communication, subject to some bound on the total number of errors. A fundamental question in this setting is to design a protocol that remains private in the presence of large number of errors.

MOTIVATION: High-throughput sequencing technologies have impacted many areas of genetic research. One such area is the identification of relatives from genetic data. The standard approach for the identification of genetic relatives collects the genomic data of all individuals and stores it in a database. Then, each pair of individuals is compared to detect the set of genetic relatives, and the matched individuals are informed. The main drawback of this approach is the requirement of sharing your genetic data with a trusted third party to perform the relatedness test. RESULTS: In this work, we propose a secure protocol to detect the genetic relatives from sequencing data while not exposing any information about their genomes. We assume that individuals have access to their genome sequences but do not want to share their genomes with anyone else. Unlike previous approaches, our approach uses both common and rare variants which provide the ability to detect much more distant relationships securely. We use a simulated data generated from the 1000 genomes data and illustrate that we can easily detect up to fifth degree cousins which was not possible using the existing methods. We also show in the 1000 genomes data with cryptic relationships that our method can detect these individuals. AVAILABILITY: The software is freely available for download at http://genetics.cs.ucla.edu/crypto/.