Thymoma CT images exhibit significant scale variations and blurred boundaries, posing a challenge to automatic segmentation. The proposed model is a multi-scale dual attention and gated skip connection network (MSDACG-Net), which suppresses redundant features in skip connections through context gating (CoT Gate) and enhances context modeling capabilities at high resolution using a multi-scale dual attention aggregation (MSDA) module. The effectiveness of the method was validated through experimentation on a thymoma CT dataset that had been self-built. A comparison of the proposed model with a strong baseline reveals that MSDACG-Net improves Dice by 1.01%, reduces HD95 by 24%, and improves Recall by 0.59%, demonstrating superior overall accuracy, boundary approximation ability, and detection robustness. Moreover, cross-modal experiments on the publicly available polysegmentation dataset Kvasir-SEG demonstrate the proposed method’s capacity for effective generalisation.

Deep learning-based defect detection of transmission line insulation equipment helps enhance power grid stability and inspection personnel safety. However, existing research still falls short of meeting practical inspection requirements [ 1 ]. To address this issue, this paper proposes a novel Is-YOLO model to improve defect detection accuracy in complex aerial inspection scenarios. The designed C3k2_IDC module adopts a multi-branch parallel structure with diverse convolutional kernels, expanding the receptive field while preserving computational efficiency. The C3k2_StarsBlock module leverages star operations to capture high-dimensional features and further promote detection accuracy. In addition, a newly designed P2/4 tiny-target detection head achieves substantial improvement in small-object detection performance. Experimental results on a UAV-captured dataset of transmission line insulator defects demonstrate that the proposed Is-YOLO model outperforms YOLOv11-n with only an 11.5% increase in model parameters. Its mAP50 rises from 84.5% to 88.7%, mAP75 from 62.3% to 67.1%, and mAP50–95 from 61.4% to 65%. With moderate computational overhead and significant performance gains, Is-YOLO can serve as an efficient solution for insulator defect detection.

Many current approaches to the medical image segmentation suffer from problems of limited perceptual range, insufficient modeling of remote contextual relation, and insufficient feature refinement. In this paper, we propose ADAU-MambaBot, a novel three-dimensional approach for the segmentation of coronary artery, which is integrating dynamically adjustable dilated convolution, symmetric attention mechanism, and a state-space architecture based on the idea of Mamba. The system contains self-adjusting dilation module, that automatically decides the receptive field sizes, and dual-direction attention, which can boost not only the channel-wise but also the spatial feature extraction. We also implement the graduated training to make the convergence more reliable. On the ImageCAS benchmark, we show that, with the given ADAU-MambaBot system, the Dice score is 83.91%, which outperforms the performance of U-MambaBot and UU-Mamba architectures. In the component analysis and the computational efficiency study, we find that although the proposed solution achieves improved segmentation accuracy and more robust training, the addition of the advanced components does cause more requirements of the computation.

Accurately predicting potential drug-drug interactions (DDIs) from multimodal data is critical for medication safety and adverse drug reaction prevention. Existing methods face challenges in modeling long-range dependencies and effectively integrating heterogeneous features from structured molecular data and unstructured text. To address these limitations, we propose C2M-Mamba, a cross-modal framework that integrates convolutional neural networks, Mamba, and cross-Mamba (CroMamba) to capture discriminative features from drug descriptions, SMILES sequences, and social media texts. The model efficiently handles long-range dependencies through state space models while enabling effective cross-modal fusion. Comprehensive evaluations on the DDIExtraction2013 dataset demonstrate that C2M-Mamba outperforms 10 state-of-the-art baselines, achieving 82.37% precision, 80.98% F1-score, and 88.73% AUC. The proposed approach also exhibits robust performance in handling class imbalance and provides interpretable predictions, offering a reliable solution for multimodal DDI prediction with potential applications in pharmacovigilance and personalized medicine.

Industrial IoVT (Internet of Video Things) still faces the dual bottleneck of insufficient accuracy and poor real-time performance in circuit board tiny defect detection. To this end, we propose RGM-YOLO (RefConv–GhostNet–CBAM-enhanced YOLOv8 ), which introduces deformable convolution and channel attention via RefConv and GhostNet modules, and experimentally validates it on the BDL-PCB (Bare Die on Laminate–Printed Circuit Board) large-scale dataset. Experimental results show that RGM-YOLO achieves 94.2% in mAP50 and 67.3% in mAP90–95, representing improvements of 2.4% and 11.2% over the baseline model, YOLOv8. The number of parameters and GFLOPs is reduced by 4.2M and 2.5G, respectively, while the FPS increases from 78 to 102. This approach offers a high-precision, low-latency defect detection paradigm for edge IoVT devices targeting small defects and can be generalized to other industrial quality-inspection scenarios.

Predicting potential drug-drug interactions (DDIs) from biomedical data plays a critical role in drug therapy, drug development, drug regulation, and public health. However, it remains challenging due to the large number of possible drug combinations, and multimodal biomedical data, which is disorder, imbalanced, more prone to linguistic errors, and difficult to label. A Semantic Cross-Attention Transformer (SCAT) model is constructed to address the above challenge. In the model, BioBERT, Doc2Vec and graph convolutional network are utilized to embed the multimodal biomedical data into vector representation, BiGRU is adopted to capture contextual dependencies in both forward and backward directions, Cross-Attention is employed to integrate the extracted features and explicitly model dependencies between them, and a feature-joint classifier is adopted to implement DDI predication (DDIP). The experiment results on the DDIExtraction-2013 dataset demonstrate that SCAT outperforms the state-of-the-art DDIP approaches. SCAT expands the application of multimodal deep learning in the field of multimodal DDIP, and can be applied to drug regulation systems to predict novel DDIs and DDI-related events.

Wearable device-based Human Activity Recognition (HAR) has attracted considerable interest with the rapid development of the Internet of things (IoT), and Federated Learning (FL) has been widely adopted in this domain for its ability to collaboratively train models across decentralized devices while preserving privacy. However, its performance is hindered by data heterogeneity arising from variations in the placement of the wearable devices, user behaviors, and physiological characteristics. In this work, we present LDA-FedHAR, a federated HAR framework designed for wearable devices by capturing more common knowledge from aligned client HAR data. It performs Local HAR Data Alignment (LDA) on each client, which is an entirely on-device alignment method that operates independently on local HAR data. By computing the transformation matrix solely from local HAR data and applying it to the data itself, LDA projects heterogeneous client data into a unified space, thereby reducing inter-client discrepancies at the source. To further enhance efficiency and robustness, we propose two IMU-specific variants, LDA(S-IMU) and LDA(C-IMU), which explore intra-and inter-IMU correlations based on practical placements of wearable devices. Experiments are conducted on 4 public HAR datasets: HHAR, Shoaib2014, OPPORTUNITY++, and PAMAP2. The results show that LDA effectively reduces inter-client discrepancies, and LDA-FedHAR along with its variants consistently outperforms state-of-the-art FL methods. Moreover, the improvements achieved by integrating LDA into other FL methods highlight its applicability.

Benefiting from the powerful feature extraction and feature correlation modeling capabilities of convolutional neural networks (CNNs) and Transformer models, these techniques have been widely used in unmanned aerial vehicle (UAV) aerial image semantic segmentation tasks. However, the ground objects in aerial images contain feature information with different scales, and existing methods directly cascade low-level visual features and high-level semantic features without processing, resulting in low semantic segmentation precision. To address these challenges, we propose a dual-encoder cross-scale attention network, which efficiently extracts local and global context information from aerial images and performs fine-grained fusion of multiscale features to improve semantic segmentation performance. First, we introduce the dual-CNN-Transformer encoder, which embeds the scan-focus window Transformer (SFWT) into CNNs as an auxiliary encoder to supplement the local feature information lost in the global context information extraction process. Second, the cross-scale lightweight integration (CSLI) module is designed, which uses a light dot-product attention mechanism (DPAM) to fusion multiscale features and reduce model calculation parameters. Finally, the linear multilayer perceptron (LMLP) is used to restore the feature map resolution while expanding the deconvolution receptive field. To validate the effectiveness of the proposed method, we conducted extensive experiments on real aerial scene datasets, including UAVid, Urban Drone, and AeroScapes. The experimental results show that our method achieves state-of-the-art performance while maintaining superior real-time efficiency. Implementation codes will be available athttps://github.com/darkseid-arch/UAVSeg.

BACKGROUND: As a key non-coding RNA molecule, miRNA profoundly affects gene expression regulation and connects to the pathological processes of several kinds of human diseases. However, conventional experimental methods for validating miRNA-disease associations are laborious. Consequently, the development of efficient and reliable computational prediction models is crucial for the identification and validation of these associations. RESULTS: In this research, we developed the PCACFMDA method to predict the potential associations between miRNAs and diseases. To construct a multidimensional feature matrix, we consider the fusion similarities of miRNA and disease and miRNA-disease pairs. We then use principal component analysis(PCA) to reduce data complexity and extract low-dimensional features. Subsequently, a tuned cascade forest is used to mine the features and output prediction scores deeply. The results of the 5-fold cross-validation using the HMDD v2.0 database indicate that the PCACFMDA algorithm achieved an AUC of 98.56%. Additionally, we perform case studies on breast, esophageal and lung neoplasms. The findings revealed that the top 50 miRNAs most strongly linked to each disease have been validated. CONCLUSIONS: Based on PCA and optimized cascade forests, we propose the PCACFMDA model for predicting undiscovered miRNA-disease associations. The experimental results demonstrate superior prediction performance and commendable stability. Consequently, the PCACFMDA is a potent instrument for in-depth exploration of miRNA-disease associations.

For semantic segmentation of remote sensing images, convolutional neural networks (CNNs) have proven to be powerful tools. However, the existing CNN-based methods have the problems of feature information loss, serious interference by clutter information, and ignoring the correlation between different scale features. To solve these problems, this article proposes a novel hidden feature-guided semantic segmentation network (HFGNet) for remote sensing images, which achieves accurate semantic segmentation by hierarchically extracting and fusing valuable feature information. Specifically, the hidden feature extraction module (HFE-M) is introduced to suppress the salient feature representation to mine more valuable hidden features. Meanwhile, the multifeature interactive fusion module (MIF-M) establishes the correlation between different features to achieve hierarchical feature fusion. The multiscale feature calibration module (MSFC) is constructed to enhance the diversity and refinement representation of hierarchical fusion features. Besides, the local-channel attention mechanism (LCA-M) is designed to improve the feature perception capability of the object region and suppress background information interference. We conducted extensive experiments on the widely used ISPRS 2-D Semantic Labeling dataset and the 15-Class Gaofen Image dataset. Experimental results demonstrate that the proposed HFGNet has advantages over several state-of-the-art methods. The source code and models are available athttps://github.com/darkseid-arch/RS-HFGNet.

Aircraft detection in synthetic aperture radar (SAR) images plays an essential role in satellite observation and military decisions. Due to discrete scattering properties, speckle noise interference, and various aircraft types, many existing methods struggle to achieve the desired detection performance. In this article, we propose an innovative semantic condition constraint guided feature aware network (SCFNet) for detecting different aircraft categories in SAR images. First, considering the discrete scattering properties of aircraft, we design a local-global feature aware module (LGA-M) and morphological-semantic feature aware module (MSF-M), which can effectively extract the fine-grained feature information contained in SAR images. Second, to effectively fuse different feature information, we construct a feature fusion pyramid (FFP), which uses different branches and paths to reasonably merge multiple feature information types and suppresses background information interference. Third, according to the structure characteristics of aircraft, the global coordinate attention mechanism (G-CAT) is presented to highlight foreground target features and suppress speckle noise interference. Finally, we construct semantic condition constraints, including constraint condition setting, semantic information calculation, and template matching, to improve aircraft localization and recognition accuracy. Extensive experiments demonstrate that the proposed SCFNet can obtain state-of-the-art performance on the SAR aircraft detection dataset, which achieves AP and F1 Score of 94.83% and 95.58%, respectively. The related implementation codes will be made publicly available at https://github.com/darkseid-arch/AirDetection.

Sonar image object detection is essential in underwater rescue and resource exploration. Although many convolution neural network (CNN)-based object detection algorithms have achieved great success in natural images. However, for underwater sonar images, problems, such as seabed reverberation noise interference, low proportion of foreground object region pixels, and poor imaging resolution, present considerable challenges to achieving accurate underwater object detection. To address these problems, we propose a novel sonar image object detector called the multilevel feature fusion network (MLFFNet). The detector consists of multiscale convolution module (MS-Conv), multilevel feature extraction module (ML-FEM), multilevel feature fusion module (ML-FFM), neighborhood channel attention mechanism (N-CAM), multiscale feature pyramid module (MS-FPN), and feature association module (FA). First, we use the MS-Conv to extract different scale feature information in the object region. Second, the ML-FEM and ML-FFM are used to obtain the local detail and global context features. Third, the N-CAM and MS-FPN are used to obtain the foreground objects’ semantic feature and position feature, and suppress the background region noise interference. Finally, we use the FA module to enhance the category and feature correlation of different objects. Extensive experiments are conducted on the real scene sonar image dataset. The experimental results demonstrate that MLFFNet performs better than other state-of-the-art object detection methods. Code and dataset are publicly athttps://github.com/darkseid-arch/SonarMLFFNet.

Aircraft detection in synthetic aperture radar (SAR) images plays an essential role in satellite observation and military decisions. Due to discrete scattering properties, speckle noise interference, and various aircraft types, many existing methods struggle to achieve the desired detection performance. In this article, we propose an innovative semantic condition constraint guided feature aware network (SCFNet) for detecting different aircraft categories in SAR images. First, considering the discrete scattering properties of aircraft, we design a local-global feature aware module (LGA-M) and morphological-semantic feature aware module (MSF-M), which can effectively extract the fine-grained feature information contained in SAR images. Second, to effectively fuse different feature information, we construct a feature fusion pyramid (FFP), which uses different branches and paths to reasonably merge multiple feature information types and suppresses background information interference. Third, according to the structure characteristics of aircraft, the global coordinate attention mechanism (G-CAT) is presented to highlight foreground target features and suppress speckle noise interference. Finally, we construct semantic condition constraints, including constraint condition setting, semantic information calculation, and template matching, to improve aircraft localization and recognition accuracy. Extensive experiments demonstrate that the proposed SCFNet can obtain state-of-the-art performance on the SAR aircraft detection dataset, which achieves AP and F1 Score of 94.83% and 95.58%, respectively. The related implementation codes will be made publicly available at https://github.com/darkseid-arch/AirDetection.

Side-scan sonar (SSS) is a vital sensor for marine survey, which is widely used in military and civilian fields. The accurate segmentation of SSS images is critical in sonar image intelligent interpretation. Existing SSS image segmentation methods have several limitations, such as insufficient feature extraction, relatively worse segmentation results for tiny target categories, and serious interference by seabed reverberation noise and bright shadow region. To overcome these issues, we propose a novel encoder-decoder architecture SSS image segmentation method based on convolution neural network (CNN). First, we extract the multi-scale feature information contained in target region using the dynamic multi-scale dilated convolution (DMDC_Conv). Second, to further obtain the global and detail feature information, we construct the adaptive receptive field mechanism block (ARFM_Block). Third, we design a feature fusion attention mechanism block (FFAM_Block) to fuse high-level and low-level feature information with different scales and suppress background information interference. Final, we construct a tree structure optimization module (TSOM) to solve the problem of pixel misclassification and obtain refine SSS image segmentation results. Extensive experiments are carried out on the constructed real scene SSS image dataset. The experimental results show that the proposed method achieves 93.24% and 90.82% of MPA and MIoU, respectively, which outperforms other state-of-the-art methods and has a substantial advantage in inference speed and calculation parameters.

Efficient and accurate recognition of plant diseases based on leaf images is a hot research topic. The plant diseased leaf images are complex and diverse. It is generally difficult to extract reliable features. In this paper, a new plant disease recognition method is proposed, based on a Modified Residual Neural Network (MRNN) and transfer learning. Compared with the classical residual neural network ResNet-50, the residual block structure in MRNN is modified. The experiment results on the AI Challenger dataset show MRNN can achieve 91.4% recognition accuracy which is higher than other classic CNN models. Combined with the Kaggle Cassava dataset, the MRNN is trained with transfer learning, which improves the accuracy, robustness and generalization ability. The experiments results show that the proposed method not only has an advantage in accuracy, but also has a significant improvement in training speed, which validates the efficiency and effectiveness of the proposed approach.

A novel supervised dimensionality reduction method called orthogonal maximum margin discriminant projection (OMMDP) is proposed to cope with the high dimensionality, complex, various, irregular-shape plant leaf image data. OMMDP aims at learning a linear transformation. After projecting the original data into a low dimensional subspace by OMMDP, the data points of the same class get as near as possible while the data points of the different classes become as far as possible, thus the classification ability is enhanced. The main differences from linear discriminant analysis (LDA), discriminant locality preserving projections (DLPP) and other supervised manifold learning-based methods are as follows: (1) In OMMDP, Warshall algorithm is first applied to constructing both of the must-link and class-class scatter matrices, whose process is easily and quickly implemented without judging whether any pairwise points belong to the same class. (2) The neighborhood density is defined to construct the objective function of OMMDP, which makes OMMDP be robust to noise and outliers. Experimental results on two public plant leaf databases clearly demonstrate the effectiveness of the proposed method for classifying leaf images.

As for gait recognition, we propose a new discriminant dimensionality reduction method, named Bimodal Discriminant Projection Analysis (BDPA) algorithm. In BDPA, a weight path-based similarity measure is designed, the intra-class scatter matrix is constructed by the weight, while the inter-class scatter matrix is constructed by the heat kernel function. Compared with the classical methods, such as Multimodal Preserving Embedding (MPE) and Minimax Risk Criterion methods, the proposed method can preserve within-class neighborhood geometry and extract between-class relevant structures for recognition by minimizing the intra-class scatter and maximizing the inter-class scatter. The experimental results on real-world gait data show that BDPA is effective and feasible for gait recognition.