Summary: The Medaka Expression Pattern Database (MEPD) is a database for gene expression patterns determined by in situ hybridization in the small freshwater fish medaka (Oryzias latipes). Data have been collected from various research groups and MEPD is developing into a central expression pattern depository within the medaka community. Gene expression patterns are described by images and terms of a detailed medaka anatomy ontology of over 4000 terms, which we have developed for this purpose and submitted to Open Biological Ontologies. Sequences have been annotated via BLAST match results and using Gene Ontology terms. These new features will facilitate data analyses using bioinformatics approaches and allow cross-species comparisons of gene expression patterns. Presently, MEPD has 19 757 entries, for 1024 of them the expression pattern has been determined. Availability: A new version has been implemented at the EMBL in Heidelberg and is now accessible at http://www.embl.de/mepd Contact: [email protected] Supplementary information: http://www.embl.de/mepd/supplement.html

GeneView is a newly developed human gene mapping library system that works on an X-Window platform. This system is designed for researchers who routinely utilize gene mapping data in the laboratory but are unfamiliar with computer technology. GeneView offers various features, including friendly user interface, fast operation and visualization facility. Genetic loci are displayed graphically with an idiogram. This system can be operated in multiple languages. A current version supports Japanese and English, and can be easily expanded to include other languages. A prototype of GeneView is now installed on a SPARC (Sun4) workstation. Because of the X-Window platform, GeneView should be compatible with various types of workstations.