OBJECTIVE: Access to palliative care (PC) is important for many patients with uncontrolled symptom burden from serious or complex illness. However, many patients who could benefit from PC do not receive it early enough or at all. We sought to address this problem by building a predictive model into a comprehensive clinical framework with the aims to (i) identify in-hospital patients likely to benefit from a PC consult, and (ii) intervene on such patients by contacting their care team. MATERIALS AND METHODS: Electronic health record data for 68 349 inpatient encounters in 2017 at a large hospital were used to train a model to predict the need for PC consult. This model was published as a web service, connected to institutional data pipelines, and consumed by a downstream display application monitored by the PC team. For those patients that the PC team deems appropriate, a team member then contacts the patient's corresponding care team. RESULTS: Training performance AUC based on a 20% holdout validation set was 0.90. The most influential variables were previous palliative care, hospital unit, Albumin, Troponin, and metastatic cancer. The model has been successfully integrated into the clinical workflow making real-time predictions on hundreds of patients per day. The model had an "in-production" AUC of 0.91. A clinical trial is currently underway to assess the effect on clinical outcomes. CONCLUSIONS: A machine learning model can effectively predict the need for an inpatient PC consult and has been successfully integrated into practice to refer new patients to PC.

Summary Power is becoming an increasingly important concern for large supercomputer centers. However, to date, there have been a dearth of studies of power usage ‘in the wild’—on production supercomputers running production workloads. In this paper, we present the initial results of a project to characterize the power usage of the three Top500 supercomputers at Los Alamos National Laboratory: Cielo, Roadrunner, and Luna (#15, #19, and #47, respectively, on the June 2012 Top500 list). Power measurements taken both at the switchboard level and within the compute racks are presented and discussed. Some noteworthy results of this study are that (1) variability in power consumption differs across architectures, even when running a similar workload and (2) Los Alamos National Laboratory's scientific workload draws, on average, only 70–75% of LINPACK power and only 40–55% of nameplate power, implying that power capping may enable a substantial reduction in power and cooling infrastructure while impacting comparatively few applications. Copyright © 2013 John Wiley & Sons, Ltd.

With the increasing prevalence of richer, more complex data sources, learning with multiple views is becoming more widespread. Multiple kernel learning (MKL) has been developed to address this problem, but in general, the solutions provided by traditional MKL are restricted to a classification objective function. In this work, we develop a novel multiple kernel learning algorithm that is based on a spectral clustering objective function which is able to find an optimal kernel weight vector for the clustering problem. We go on to show how this optimization problem can be cast as a semidefinite program and efficiently solved using off-the-shelf interior point methods.