As a pathology, the so-called 'silent killer' a.k.a. high blood pressure (HBP) has no noticeable warning symptoms until it is usually too late. Serious heart disease is a major cause of angina and chronic spasm leading to heart attack : kidney diseases and failures are simultaneously causes and consequences of those conditions. In this paper, we give an object-oriented specification of kidney failures at their multi functional levels, and we give suggestions for managing the catch-22 cross regulation problem between HBP and dialysis renal functions. As a specification tool, we use UML (unified modelling language) as it offers total industrial compatibility and the safest standard way to describe medical organ failure processes. As a major filtering organ, kidney has been modelized as a target for ultrasonography via case-based specification, and as industrial pilot examples for automation and transplantation safety.

This study is a part of an effort to simulate the 29-state self-reproducing cellular automaton described by John von Neumann in a manuscript that dates back to 1952. We are interested in the programming of very large SIMD arrays which, as a consequence of scaling them up, incorporate some features of cellular automata. Designing tools for programming them requires an experimental ground: considering that von Neumann's 29-state is the only known very large and complex cellular automaton, its simulation is a necessary first step. Embedded in a two-dimensional cellular array, using 29 states per cell and 5-cell neighborhood, this automaton exhibits the capabilities of universal computation and universal construction.