Evaluating the performance of low-light image enhancement (LLE) is highly subjective, thus making integrating human preferences into LLE a necessity. Existing methods fail to consider this and present a series of potentially valid heuristic criteria for training LLE models. In this paper, we propose a new paradigm, i.e., aesthetics-guided low-light image enhancement (ALL-E), which introduces aesthetic preferences to LLE and motivates training in a reinforcement learning framework with an aesthetic reward. Each pixel, functioning as an agent, refines itself by recursive actions. We further present ALL-E+, an extended version of ALL-E, which casts a two-stage aesthetics-guided enhancement and denoising. ALL-E+ achieves low-light enhancement and denoising compensation sequentially in a unified framework, resulting in significant improvements in both subjective visual experience and objective evaluation. Extensive experiments show that integrating aesthetic preferences can further improve the visual experience of enhanced images. Our results on various benchmarks also demonstrate the superiority of our method over state-of-the-art methods.

Despite the recent theoretical boom in Sample Entropy based algorithms for the analysis of physiological and pathological systems, the major issue which prevents their more widespread use remains that of large computational load, particularly in the studies of quantification of structural richness in data. This issue becomes even more prohibitive when it comes to large data sizes and real-time processing. To this end, a new Classification Angle (ClassA) Entropy is introduced for the quantification of structural complexity of real world signals, based on an improved Second Order Difference Plot and Shannon Entropy. In comparison with existing nonlinear techniques, including Real Sum Angle index, Phase Entropy, Gridded Distribution Entropy and Cosine Similarity Entropy, the proposed method offers the advantages of a minimal number of tunable parameters, lower requirement of data size, wider application field and large relaxation of computational load. Simulations on real world physiological data support the approach.

Evaluating the performance of low-light image enhancement (LLE) is highly subjective, thus making integrating human preferences into image enhancement a necessity. Existing methods fail to consider this and present a series of potentially valid heuristic criteria for training enhancement models. In this paper, we propose a new paradigm, i.e., aesthetics-guided low-light image enhancement (ALL-E), which introduces aesthetic preferences to LLE and motivates training in a reinforcement learning framework with an aesthetic reward. Each pixel, functioning as an agent, refines itself by recursive actions, i.e., its corresponding adjustment curve is estimated sequentially. Extensive experiments show that integrating aesthetic assessment improves both subjective experience and objective evaluation. Our results on various benchmarks demonstrate the superiority of ALL-E over state-of-the-art methods. Source code: https://dongl-group.github.io/project pages/ALLE.html

Depression is one of the most common mental health disorders, and a large number of depressed people commit suicide each year. Potential depression sufferers usually do not consult psychological doctors because they feel ashamed or are unaware of any depression, which may result in severe delay of diagnosis and treatment. In the meantime, evidence shows that social media data provides valuable clues about physical and mental health conditions. In this paper, we argue that it is feasible to identify depression at an early stage by mining online social behaviours. Our approach, which is innovative to the practice of depression detection, does not rely on the extraction of numerous or complicated features to achieve accurate depression detection. Instead, we propose a novel classifier, namely, Cost-sensitive Boosting Pruning Trees (CBPT), which demonstrates a strong classification ability on two publicly accessible Twitter depression detection datasets. To comprehensively evaluate the classification capability of CBPT, we use additional three datasets from the UCI machine learning repository and CBPT obtains appealing classification results against several state of the arts boosting algorithms. Finally, we comprehensively explore the influence factors for the model prediction, and the results manifest that our proposed framework is promising for identifying Twitter users with depression.

Low-light image enhancement (LLE) remains challenging due to the unfavorable prevailing low-contrast and weak-visibility problems of single RGB images. In this paper, we respond to the intriguing learning-related question -- if leveraging both accessible unpaired over/underexposed images and high-level semantic guidance, can improve the performance of cutting-edge LLE models? Here, we propose an effective semantically contrastive learning paradigm for LLE (namely SCL-LLE). Beyond the existing LLE wisdom, it casts the image enhancement task as multi-task joint learning, where LLE is converted into three constraints of contrastive learning, semantic brightness consistency, and feature preservation for simultaneously ensuring the exposure, texture, and color consistency. SCL-LLE allows the LLE model to learn from unpaired positives (normal-light)/negatives (over/underexposed), and enables it to interact with the scene semantics to regularize the image enhancement network, yet the interaction of high-level semantic knowledge and the low-level signal prior is seldom investigated in previous methods. Training on readily available open data, extensive experiments demonstrate that our method surpasses the state-of-the-arts LLE models over six independent cross-scenes datasets. Moreover, SCL-LLE's potential to benefit the downstream semantic segmentation under extremely dark conditions is discussed. Source Code: https://github.com/LingLIx/SCL-LLE.

Estimating the changes of epidemiological parameters, such as instantaneous reproduction number, Rt, is important for understanding the transmission dynamics of infectious diseases. Current estimates of time-varying epidemiological parameters often face problems such as lagging observations, averaging inference, and improper quantification of uncertainties. To address these problems, we propose a Bayesian data assimilation framework for time-varying parameter estimation. Specifically, this framework is applied to estimate the instantaneous reproduction number Rt during emerging epidemics, resulting in the state-of-the-art 'DARt' system. With DARt, time misalignment caused by lagging observations is tackled by incorporating observation delays into the joint inference of infections and Rt; the drawback of averaging is overcome by instantaneously updating upon new observations and developing a model selection mechanism that captures abrupt changes; the uncertainty is quantified and reduced by employing Bayesian smoothing. We validate the performance of DARt and demonstrate its power in describing the transmission dynamics of COVID-19. The proposed approach provides a promising solution for making accurate and timely estimation for transmission dynamics based on reported data.

Automated analysis of mouse behaviours is crucial for many applications in neuroscience. However, quantifying mouse behaviours from videos or images remains a challenging problem, where pose estimation plays an important role in describing mouse behaviours. Although deep learning based methods have made promising advances in human pose estimation, they cannot be directly applied to pose estimation of mice due to different physiological natures. Particularly, since mouse body is highly deformable, it is a challenge to accurately locate different keypoints on the mouse body. In this paper, we propose a novel Hourglass network based model, namely Graphical Model based Structured Context Enhancement Network (GM-SCENet) where two effective modules, i.e., Structured Context Mixer (SCM) and Cascaded Multi-level Supervision (CMLS) are subsequently implemented. SCM can adaptively learn and enhance the proposed structured context information of each mouse part by a novel graphical model that takes into account the motion difference between body parts. Then, the CMLS module is designed to jointly train the proposed SCM and the Hourglass network by generating multi-level information, increasing the robustness of the whole network. Using the multi-level prediction information from SCM and CMLS, we develop an inference method to ensure the accuracy of the localisation results. Finally, we evaluate our proposed approach against several baselines on our Parkinson’s Disease Mouse Behaviour (PDMB) and the standard DeepLabCut Mouse Pose datasets. The experimental results show that our method achieves better or competitive performance against the other state-of-the-art approaches.

Home-cage social behaviour analysis of mice is an invaluable tool to assess therapeutic efficacy of neurodegenerative diseases. Despite tremendous efforts made within the research community, single-camera video recordings are mainly used for such analysis. Because of the potential to create rich descriptions for mouse social behaviors, the use of multi-view video recordings for rodent observations is increasingly receiving much attention. However, identifying social behaviours from various views is still challenging due to the lack of correspondence across data sources. To address this problem, we here propose a novel multi-view latent-attention and dynamic discriminative model that jointly learns view-specific and view-shared sub-structures, where the former captures unique dynamics of each view whilst the latter encodes the interaction between the views. Furthermore, a novel multi-view latent-attention variational autoencoder model is introduced in learning the acquired features, enabling us to learn discriminative features in each view. Experimental results on the standard CRMI13 and our multi-view Parkinson's Disease Mouse Behaviour (PDMB) datasets demonstrate that our proposed model outperforms the other state of the arts technologies, has lower computational cost than the other graphical models and effectively deals with the imbalanced data problem.

Simultaneous feature selection and clustering is a major challenge in unsupervised learning. In particular, there has been significant research into saliency measures for features that result in good clustering. However, as datasets become larger and more complex, there is a need to adopt a finer-grained approach to saliency by measuring it in relation to a part of a model. Another issue is learning the feature saliency and advanced model parameters. We address the first by presenting a novel Gaussian mixture model, which explicitly models the dependency of individual mixture components on each feature giving a new component-based feature saliency measure. For the second, we use Markov Chain Monte Carlo sampling to estimate the model and hidden variables. Using a synthetic dataset, we demonstrate the superiority of our approach, in terms of clustering accuracy and model parameter estimation, over an approach using a model-based feature saliency with expectation maximisation. We performed an evaluation of our approach with six synthetic trajectory datasets obtaining an average clustering accuracy of 97 percent. To demonstrate the generality of our approach, we applied it to a network traffic flow dataset obtaining an accuracy of 93 percent for intrusion detection. Finally, we performed a comparison with state-of-the-art clustering techniques using three real-world trajectory datasets of vehicle traffic. Our approach achieved an average clustering accuracy of 96 percent compared to 77-95 percent for the other techniques. In conclusion, for the datasets considered, component based feature saliency measures gave improved clustering over those based on whole models.

Automated segmentation of brain glioma plays an active role in diagnosis decision, progression monitoring and surgery planning. Based on deep neural networks, previous studies have shown promising technologies for brain glioma segmentation. However, these approaches lack powerful strategies to incorporate contextual information of tumor cells and their surrounding, which has been proven as a fundamental cue to deal with local ambiguity. In this work, we propose a novel approach named Context-Aware Network (CANet) for brain glioma segmentation. CANet captures high dimensional and discriminative features with contexts from both the convolutional space and feature interaction graphs. We further propose context guided attentive conditional random fields which can selectively aggregate features. We evaluate our method using publicly accessible brain glioma segmentation datasets BRATS2017, BRATS2018 and BRATS2019. The experimental results show that the proposed algorithm has better or competitive performance against several State-of-The-Art approaches under different segmentation metrics on the training and validation sets.

Multipopulation is an effective optimization component often embedded into evolutionary algorithms to solve optimization problems. In this paper, a new multipopulation-based multiobjective genetic algorithm (MOGA) is proposed, which uses a unique cross-subpopulation migration process inspired by biological processes to share information between subpopulations. Then, a Markov model of the proposed multipopulation MOGA is derived, the first of its kind, which provides an exact mathematical model for each possible population occurring simultaneously with multiple objectives. Simulation results of two multiobjective test problems with multiple subpopulations justify the derived Markov model, and show that the proposed multipopulation method can improve the optimization ability of the MOGA. Also, the proposed multipopulation method is applied to other multiobjective evolutionary algorithms (MOEAs) for evaluating its performance against the IEEE Congress on Evolutionary Computation multiobjective benchmarks. The experimental results show that a single-population MOEA can be extended to a multipopulation version, while obtaining better optimization performance.

Automated recognition of mouse behaviors is crucial in studying psychiatric and neurologic diseases. To achieve this objective, it is very important to analyze the temporal dynamics of mouse behaviors. In particular, the change between mouse neighboring actions is swift in a short period. In this paper, we develop and implement a novel hidden Markov model (HMM) algorithm to describe the temporal characteristics of mouse behaviors. In particular, we here propose a hybrid deep learning architecture, where the first unsupervised layer relies on an advanced spatial-temporal segment Fisher vector encoding both visual and contextual features. Subsequent supervised layers based on our segment aggregate network are trained to estimate the state-dependent observation probabilities of the HMM. The proposed architecture shows the ability to discriminate between visually similar behaviors and results in high recognition rates with the strength of processing imbalanced mouse behavior datasets. Finally, we evaluate our approach using JHuang's and our own datasets, and the results show that our method outperforms other state-of-the-art approaches.

Automatic emotion recognition based on electroencephalo-graphic (EEG) signals has received increasing attention in recent years. The Deep Residual Networks (ResNets) can solve vanishing gradient problem and exploding gradient problem well in computer vision and can learn more profound semantic information. And for traditional methods, frequency features often play important role in signal processing area. Thus, in this paper, we use the pre-trained ResNets to extract deep semantic information and the linear-frequency cepstral coefficients (LFCC) as features from raw EEG signals. Then the two features are fused to improve the emotion classification performance of our approach. Moreover, several classifiers are used for our fused features to evaluate the performance and it shows that the proposed approach is effective for emotion classification. We find that the best performance is achieved when use k-nearst neighbor (KNN) as classifier, and we provide a detailed discussion for the reason.

The concept of muscle synergies has proven to be an effective method for representing patterns of muscle activation. The number of degrees of freedom to be controlled are reduced while also providing a flexible platform for producing detailed movements using synergies as building blocks. It has previously been shown that small components of movement are crucial to producing precise and coordinated movement. Methods which focus on the variance of the data make it possible to overlook these small components in the synergy extraction process. However, algorithms which address the inherent complexity in the neuromuscular system are lacking. To that end we propose a new nonnegative matrix factorization algorithm which employs a cross fuzzy entropy similarity measure, thus, extracting muscle synergies which preserve the complexity of the recorded muscular data. The performance of the proposed algorithm is illustrated on representative EMG data.

A novel method to evaluate the statistical significance differences between the groups of coma and brain death patients is presented. This is achieved based on the electroencephalogram (EEG) and by using a collaborative filtering structure with the least mean square (LMS) and least mean phase (LMP) adaptive filters. By virtue of a complex-valued representation of pair-wise EEG signals, the evolution of the mixing parameter is used as an indicator of the fundamental amplitude-phase relationships of EEG recordings. Simulations illustrate the suitability of this approach to differentiate between the coma and quasi-brain-death states.