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Sonja Funke

dblp:97/552 · DBLP profile ↗
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1ranked-venue papers
0as first author
0since 2021 · last 2007
—ORCID · none

Domains — the database's venue-derived domains; a paper can count in several

Applied, interdisciplinary, general and emerging computing · 1

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
1 paper
Bioinformatics and computational biology · 100%

Topics — the 4 heaviest of 4, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Bioinformatics and computational biology
cytochrome p450
0.112007
The Cytochrome P450 Engineering Database: a navigation and prediction tool for the cytochrome P450 protein family · Bioinform. 2007
Bioinformatics and computational biology › biological database
protein family database
0.112007
The Cytochrome P450 Engineering Database: a navigation and prediction tool for the cytochrome P450 protein family · Bioinform. 2007
Bioinformatics and computational biology › protein structure analysis
protein sequence-structure analysis
0.112007
The Cytochrome P450 Engineering Database: a navigation and prediction tool for the cytochrome P450 protein family · Bioinform. 2007
Bioinformatics and computational biology › protein sequence analysis
sequence-function relationship
0.112007
The Cytochrome P450 Engineering Database: a navigation and prediction tool for the cytochrome P450 protein family · Bioinform. 2007

Methods — techniques the papers use, named apart from their topics

phylogenetic analysis · 0.1multiple sequence alignment · 0.1hidden markov model · 0.1
YearPublicationVenuePosition
2007 The Cytochrome P450 Engineering Database: a navigation and prediction tool for the cytochrome P450 protein family
abstract
SUMMARY: The Cytochrome P450 Engineering Database (CYPED) has been designed to serve as a tool for a comprehensive and systematic comparison of protein sequences and structures within the vast and diverse family of cytochrome P450 monooxygenases (CYPs). The CYPED currently integrates sequence and structure data of 3911 and 25 proteins, respectively. Proteins are grouped into homologous families and superfamilies according to Nelson's classification. Nonclassified CYP sequences are assigned by similarity. Functionally relevant residues are annotated. The web accessible version contains multisequence alignments, phylogenetic trees and HMM profiles. The CYPED is regularly updated and supplies all data for download. Thus, it provides a valuable data source for phylogenetic analysis, investigation of sequence-function relationships and the design of CYPs with improved biochemical properties. ABBREVIATIONS: Cytochrome P450 Engineering Database, CYPED; cytochrome P450 monooxygenase, CYP; Hidden Markov Model, HMM. AVAILABILITY: www.cyped.uni-stuttgart.de
Markus Fischer 0002, Michael Knoll, Demet Sirim, Florian Wagner 0005, Sonja Funke, Jürgen Pleiss
Bioinform.5