The evolution of malware has led to the development of increasingly sophisticated evasion techniques, significantly escalating the challenges for researchers in obtaining and labeling new instances for analysis. Conventional deep learning detection approaches struggle to identify new malware variants with limited sample availability. Recently, researchers have proposed few‐shot detection models to address the above issues. However, existing studies predominantly focus on model‐level improvements, overlooking the potential of domain adaptation to leverage the unique characteristics of malware. Motivated by these challenges, we propose a few‐shot learning‐based malware family detection framework (MalFSLDF). We introduce a novel method for malware representation using structural features and a feature fusion strategy. Specifically, our framework employs contrastive learning to capture the unique textural features of malware families, enhancing the identification capability for novel malware variants. In addition, we integrate entropy graphs (EGs) and gray‐level co‐occurrence matrices (GLCMs) into the feature fusion strategy to enrich sample representations and mitigate information loss. Furthermore, a domain alignment strategy is proposed to adjust the feature distribution of samples from new classes, enhancing the model’s generalization performance. Finally, comprehensive evaluations of the MaleVis and BIG‐2015 datasets show significant performance improvements in both 5‐way 1‐shot and 5‐way 5‐shot scenarios, demonstrating the effectiveness of the proposed framework.