MOTIVATION: Large-scale omics resources, including The Cancer Genome Atlas, Genomics of Drug Sensitivity in Cancer, and the Cancer Dependency Map, have become essential for cancer research. However, these datasets are distributed across different platforms, formats and analysis frameworks, which limits their practical use by researchers without extensive computational expertise. RESULTS: We developed CancerOmicsStudio (CoS), a web server for integrative and interpretable analysis of multi-omics cancer data across 33 cancer types. CoS provides five major modules: CosAI, Traditional Analysis, Drug Sensitivity, CRISPR Dependency and Single-Cell Tumor Microenvironment. The Traditional Analysis module supports expression comparison, diagnostic evaluation, survival analysis, enrichment analysis and gene correlation. The Drug Sensitivity and CRISPR Dependency modules enable systematic evaluation of gene-drug response associations and gene essentiality in cancer cell lines. The Single-Cell Tumor Microenvironment module supports tumor microenvironment analysis at single-cell resolution. In total, approximately 1.23 million results have been precomputed to enable rapid retrieval. CosAI further allows users to submit natural-language queries and obtain results through a Real-time Analysis as Retrieval framework, with responses summarized by a lightweight language model. AVAILABILITY AND IMPLEMENTATION: CancerOmicsStudio is freely available at Zenodo (doi: 10.5281/zenodo.18744990) and https://cos.wanglab.bio.

Abstract Recent advances in deep convolutional neural networks have shown improved performance in face super‐resolution through joint training with other tasks such as face analysis and landmark prediction. However, these methods have certain limitations. One major limitation is the requirement for manual marking information on the dataset for multi‐task joint learning. This additional marking process increases the computational cost of the network model. Additionally, since prior information is often estimated from low‐quality faces, the obtained guidance information tends to be inaccurate. To address these challenges, a novel Decoder Structure Guided CNN‐Transformer Network (DCTNet) is introduced, which utilises the newly proposed Global‐Local Feature Extraction Unit (GLFEU) for effective embedding. Specifically, the proposed GLFEU is composed of an attention branch and a Transformer branch, to simultaneously restore global facial structure and local texture details. Additionally, a Multi‐Stage Feature Fusion Module is incorporated to fuse features from different network stages, further improving the quality of the restored face images. Compared with previous methods, DCTNet improves Peak Signal‐to‐Noise Ratio by 0.23 and 0.19 dB on the CelebA and Helen datasets, respectively. Experimental results demonstrate that the designed DCTNet offers a simple yet powerful solution to recover detailed facial structures from low‐quality images.