Identification of seismic activity levels in coal mines is important to avoid accidents such as rockburst.Creating an early warning system that can save lives requires an automated way of predicting.This study proposes a prediction algorithm for the AAIA ′ 16 Data Mining Challenge: Predicting Dangerous Seismic Events in Active Coal Mines that is based on transient activity features along with average indicators evaluated by a Fisher's linear discriminant analysis.Performance evaluation experiments on the training datasets revealed an accuracy level of around 0.9438 while the performance on the test dataset was at a level of 0.9297.These results suggest that the proposed approach achieves high accuracy in predicting danger seismic events while maintaining low complexity.

This paper proposes a new method for automated clustering of high dimensional datasets. The method is based on a recursive binary division strategy that successively divides an original dataset into distinct clusters. Each binary division is carried out using a model-free expectation maximization scheme that exploits the posterior probability computation capability of the quasi-supervised learning algorithm. The divisions are carried out until a division cost exceeds an adaptively determined limit. Experiment results on synthetic as well as real multi-color flow cytometry datasets showed that the proposed method can accurately capture the prominent clusters without requiring any knowledge on the number of clusters or their distribution models.

We propose hierarchical motif vectors to represent local amino acid sequence configurations for predicting the functional attributes of amino acid sites on a global scale in a quasi-supervised learning framework. The motif vectors are constructed via wavelet decomposition on the variations of physico-chemical amino acid properties along the sequences. We then formulate a prediction scheme for the functional attributes of amino acid sites in terms of the respective motif vectors using the quasi-supervised learning algorithm that carries out predictions for all sites in consideration using only the experimentally verified sites. We have carried out comparative performance evaluation of the proposed method on the prediction of N-glycosylation of 55,184 sites possessing the consensus N-glycosylation sequon identified over 15,104 human proteins, out of which only 1,939 were experimentally verified N-glycosylation sites. In the experiments, the proposed method achieved better predictive performance than the alternative strategies from the literature. In addition, the predicted N-glycosylation sites showed good agreement with existing potential annotations, while the novel predictions belonged to proteins known to be modified by glycosylation.

BACKGROUND: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles from publicly available microarray datasets of cancer (breast, lymphoma and renal) samples linked to clinical information with an iterative machine learning algorithm. ROC curves were used to assess the prediction error of each profile for classification. We compared the prediction error of profiles correlated with molecular phenotype against profiles correlated with relapse-free status. Prediction error of profiles identified with supervised univariate feature selection algorithms were compared to profiles selected randomly from a) all genes on the microarray platform and b) a list of known disease-related genes (a priori selection). We also determined the relevance of expression profiles on test arrays from independent datasets, measured on either the same or different microarray platforms. RESULTS: Highly discriminative expression profiles were produced on both simulated gene expression data and expression data from breast cancer and lymphoma datasets on the basis of ER and BCL-6 expression, respectively. Use of relapse-free status to identify profiles for prognosis prediction resulted in poorly discriminative decision rules. Supervised feature selection resulted in more accurate classifications than random or a priori selection, however, the difference in prediction error decreased as the number of features increased. These results held when decision rules were applied across-datasets to samples profiled on the same microarray platform. CONCLUSION: Our results show that many gene sets predict molecular phenotypes accurately. Given this, expression profiles identified using different training datasets should be expected to show little agreement. In addition, we demonstrate the difficulty in predicting relapse directly from microarray data using supervised machine learning approaches. These findings are relevant to the use of molecular profiling for the identification of candidate biomarker panels.

We propose a method to simulate atrophy and other similar volumetric change effects on medical images. Given a desired level of atrophy, we find a dense warping deformation that produces the corresponding levels of volumetric loss on the labeled tissue using an energy minimization strategy. Simulated results on a real brain image indicate that the method generates realistic images of tissue loss. The method does not make assumptions regarding the mechanics of tissue deformation, and provides a framework where a pre-specified pattern of atrophy can readily be simulated. Furthermore, it provides exact correspondences between images prior and posterior to the atrophy that can be used to evaluate provisional image registration and atrophy quantification algorithms.

We propose a method for enforcing topology preservation and smoothness onto a given displacement field. We first analyze the conditions for topology preservation on two- and three-dimensional displacement fields over a discrete rectangular grid. We then pose the problem of finding the closest topology preserving displacement field in terms of its complete set of gradients, which we later solve using a cyclic projections framework. Adaptive smoothing of a displacement field is then formulated as an extension of topology preservation, via constraints imposed on the Jacobian of the displacement field. The simulation results indicate that this technique is a fast and reliable method to estimate a topology preserving displacement field from a noisy observation that does not necessarily preserve topology. They also show that the proposed smoothing method can render morphometric analysis methods that are based on displacement field of shape transformations more robust to noise without removing important morphologic characteristics.

We present a novel nearest neighbor rule-based implementation of the structural risk minimization principle to address a generic classification problem. We propose a fast reference set thinning algorithm on the training data set similar to a support vector machine approach. We then show that the nearest neighbor rule based on the reduced set implements the structural risk minimization principle, in a manner which does not involve selection of a convenient feature space. Simulation results on real data indicate that this method significantly reduces the computational cost of the conventional support vector machines, and achieves a nearly comparable test error performance.

We present a novel nearest neighbor rule-based implementation of the structural risk minimization principle to address a generic classification problem. We propose a fast reference set thinning algorithm on the training data set similar to a support vector machine approach. We then show that the nearest neighbor rule based on the reduced set implements the structural risk minimization principle, in a manner, which does not involve selection of a convenient feature space. Simulation results on real data indicate that this method significantly reduces the computational cost of the conventional support vector machines, and achieves a nearly comparable test error performance.

In this paper, we present a novel nearest neighbor rule-based implementation of the structural risk minimization principle to address a generic classification problem. We propose a fast reference set thinning algorithm on the training data set similar to a support vector machine (SVM) approach. We then show that the nearest neighbor rule based on the reduced set implements the structural risk minimization principle, in a manner which does not involve selection of a convenient feature space. Simulation results on real data indicate that this method significantly reduces the computational cost of the conventional SVMs, and achieves a nearly comparable test error performance.

This paper investigates vector space methods of reconstructing a surface from a given needle map in discrete image settings. We first describe the subset of the gradient space corresponding to uniformly integrable surfaces in terms of an orthonormal. set of gradient fields. We then formulate the minimum norm solution to the surface reconstruction problem from a given set of gradients, and show that the solution corresponds to an equivalence class of surfaces. Next, we relax the uniform integrability condition to partial integrability by modifying the feasible subspace. We show that partial integrability enforced as such allows reconstruction of surfaces which are not uniformly integrable.