The hypothesis of this study is to verify the sensory dominance with the combinations of three sensory modalities (Audio-Haptics (AH), Visual-Haptics (VH), Audio-Visual-Haptics (AVH)) using Virtual Reality (VR) based Cardiopulmonary Resuscitation (CPR) simulator. To test this hypothesis three experiments with three different groups of participants were conducted with the above three modes of combinations. Finally, three groups were tested for their CPR performance on an unknown linear chest stiffness of mannequin-based CPR simulator and their performance score was compared. The % mean and standard deviation of the performance score (p-value: 0.00006) in the testing phase for group A-AH, B-VH, and C-AVH is 77.95%±8.27%, 89.47%±6.19%, and 91.73%±3.14% respectively. The results show that the group who trained with the three sensory modalities have better performance than that of the other two groups. Our future work is to incorporate rescue breathing in the CPR training simulator for better skill training.