This study explores the motivations driving Chinese consumers to share information about aquatic product safety risks related to radioactive wastewater discharge on social media, with a specific focus on the role of Artificial Intelligence Generated Content (AIGC) and prior information-seeking activities. The study examines key variables such as risk perception, outcome expectations, and the influence of AIGC literacy in shaping attitudes, social norms, and sharing efficacy. Data from 501 participants were analyzed using structural equation modeling. The findings indicate that risk evaluations and personal outcome expectations significantly motivate information sharing, while social expectations deter it. Additionally, AIGC literacy enhances both knowledge acquisition and sharing efficacy, while prior information seeking increases self-efficacy and risk perception, further fostering information sharing. These results provide critical insights into how environmental risk information is processed and disseminated on social media, emphasizing AIGC’s role in influencing this process.

Thymic stromal lymphopoietin is a key cytokine involved in the pathogenesis of asthma and other allergic diseases. Targeting TSLP and its signaling pathways is increasingly recognized as an effective strategy for asthma treatment. This study focused on enhancing the affinity of the T6 antibody, which specifically targets TSLP, by integrating computational and experimental methods. The initial affinity of the T6 antibody for TSLP was lower than the benchmark antibody AMG157. To improve this, we utilized alanine scanning, molecular docking, and computational tools including mCSM-PPI2 and GEO-PPI to identify critical amino acid residues for site-directed mutagenesis. Subsequent mutations and experimental validations resulted in an antibody with significantly enhanced blocking capacity against TSLP. Our findings demonstrate the potential of computer-assisted techniques in expediting antibody affinity maturation, thereby reducing both the time and cost of experiments. The integration of computational methods with experimental approaches holds great promise for the development of targeted therapeutic antibodies for TSLP-related diseases.

This paper presents the method that underlies our submission to the popularity prediction task of Social Media Prediction Challenge 2017. The task is designed to predict the impact of sharing different posts for a publisher on social media. There are many factors that influence image popularity; these include not only the visual features of the image, but also the social features, such as user characteristics of its poster and even the upload time. In this project, we propose a fast and effective framework for popularity prediction. First, we investigate and extract visual and social features of images. For the visual feature, we introduce 1) global feature descriptors, such as Local Binary Pattern and Color Names, 2) local feature descriptors, such as Local Maximal Occurrence, and 3) deep features. For the social feature, we adopt users features (average views, group count, and member count), post features (title length, description length, and tag count), and time features (month, weekday, day, and hour). Furthermore, we fed a fusion of multi-feature to Linear Regression, Matrix Factorization based on Time and feature Cluster, and Support Vector Regression models respectively, and present comparative analysis of the prediction results. Finally, we choose the best model to predict the popularity scores of the test images. Experimental results demonstrate that our method can achieve 0.8581, 1.4062 and 0.8625 in terms of Spearman Ranking Correlation, Mean Absolute Error, and Mean Squared Error, respectively.