Accurate segmentation of lung cancer in pathology slides is a critical step in improving patient care. We proposed the ACDC@LungHP (Automatic Cancer Detection and Classification in Whole-slide Lung Histopathology) challenge for evaluating different computer-aided diagnosis (CADs) methods on the automatic diagnosis of lung cancer. The ACDC@LungHP 2019 focused on segmentation (pixel-wise detection) of cancer tissue in whole slide imaging (WSI), using an annotated dataset of 150 training images and 50 test images from 200 patients. This paper reviews this challenge and summarizes the top 10 submitted methods for lung cancer segmentation. All methods were evaluated using metrics using the precision, accuracy, sensitivity, specificity, and DICE coefficient (DC). The DC ranged from 0.7354 ±0.1149 to 0.8372 ±0.0858. The DC of the best method was close to the inter-observer agreement (0.8398 ±0.0890). All methods were based on deep learning and categorized into two groups: multi-model method and single model method. In general, multi-model methods were significantly better (p 0.01) than single model methods, with mean DC of 0.7966 and 0.7544, respectively. Deep learning based methods could potentially help pathologists find suspicious regions for further analysis of lung cancer in WSI.

This paper presents a novel algorithm for automatic detection of Glottal Closure Instants (GCI) from the speech signal. Our approach is based on a novel multiscale method that relies on precise estimation of a multiscale parameter at each time instant in the signal domain. This parameter quantifies the degree of signal singularity at each sample from a multi-scale point of view and thus its value can be used to classify signal samples accordingly. We use this property to develop a simple algorithm for detection of GCIs and we show that for the case of clean speech, our algorithm performs almost as well as a recent state-of-the-art method. Next, by performing a comprehensive comparison in presence of 14 different types of noises, we show that our method is more accurate (particularly for very low SNRs). Our method has lower computational times compared to others and does not rely on an estimate of pitch period or any critical choice of parameters.

INTERSPEECH 2012

In an earlier work, we proposed a novel phonetic segmentation method based on speech analysis under the Microcanonical Multiscale Formalism (MMF). The latter relies on the computation of local geometrical parameters, singularity exponents (SE). We showed that SE convey valuable information about the local dynamics of speech that can readily and simply used to detect phoneme boundaries. By performing error analysis of our original algorithm, in this paper we propose a 2-steps technique which better exploits SE to improve the segmentation accuracy. In the first step, we detect the boundaries of the original signal and of a low-pass filtred version, and we consider the union of all detected boundaries as candidates. In the second step, we use a hypothesis test over the local SE distribution of the original signal to select the final boundaries. We carry out a detailed evaluation and comparison over the full training set of the TIMIT database which could be useful to other researchers for comparison purposes. The results show that the new algorithm not only outperforms the original one, but also is significantly much more accurate than state-of-the-art ones.

International audience