The task of Knowledge-Based Question Generation (KBQG) involves generating natural language questions from structured knowledge sources, posing unique challenges in balancing linguistic diversity and semantic relevance. Existing models often focus on maximizing surface-level similarity to ground-truth questions, neglecting the need for diverse syntactic forms and leading to semantic drift during generation. To overcome these challenges, we propose Refine-Reinforced Diverse Question Generation (R2DQG), a two-phase framework leveraging a generation-then-refinement paradigm. The Generator first constructs a diverse set of expressive templates using dependency parse tree similarity, capturing a wide range of syntactic patterns and styles. These templates guide the creation of question drafts, ensuring both diversity and semantic relevance. In the second phase, a Corrector module refines the drafts to mitigate semantic drift and enhance overall coherence and quality. Experiments on public datasets show that R2DQG outperforms state-of-the-art models in generating diverse, contextually accurate questions. Moreover, synthetic datasets generated by R2DQG enhance downstream QA performance, underscoring the practical utility of our approach.

Recent advances in Molecular Graph-Language Models (MGLMs) have demonstrated promising capabilities in molecular understanding tasks. However, existing approaches face critical limitations: (1) shallow alignment methods which employ identical processing modules for both modalities, resulting in compromised expressiveness and catastrophic forgetting of pre-trained language capabilities; and (2) over-reliance on high-level molecular representations that inadequately capture fine-grained structural information essential for comprehensive molecular understanding. To address these challenges, we present DeepMolTex, a novel framework for Deep fusion of Molecular structure and Textual representations across multiple scales. Our approach introduces a Mixture of Modality Experts (MoME) architecture that facilitates deep alignment between molecular graph features and large language models while preserving language capabilities, and a multi-scale graph projector that extracts and aligns molecular features at atom, motif, and molecule levels. Experimental results demonstrate that DeepMolTex significantly outperforms existing methods on fundamental molecular understanding tasks, including molecule description generation and IUPAC name prediction, while effectively preserving the language capabilities of the pre-trained LLM.

Unified Medical Image Segmentation (UMIS) is critical for comprehensive anatomical assessment but faces challenges due to multi-scale structural heterogeneity. Conventional pixel-based approaches, lacking object-level anatomical insight and inter-organ relational modeling, struggle with morphological complexity and feature conflicts, limiting their efficacy in UMIS. We propose Mamba Snake, a novel deep snake framework enhanced by state space modeling for UMIS. Mamba Snake frames multi-contour evolution as a hierarchical state space atlas, effectively modeling macroscopic inter-organ topological relationships and microscopic contour refinements. We introduce a snake-specific vision state space module, the Mamba Evolution Block (MEB), which leverages effective spatiotemporal information aggregation for adaptive refinement of complex morphologies. Energy map shape priors further ensures robust long-range contour evolution in heterogeneous data. Additionally, a dual-classification synergy mechanism is incorporated to concurrently optimize detection and segmentation, mitigating under-segmentation of microstructures in UMIS. Extensive evaluations across five clinical datasets reveal Mamba Snake's superior performance.