We propose a method for concept-based medical image retrieval that is a superset of existing semantic-based image retrieval methods. We conceive of a concept as an incremental and interactive formalization of the user's conception of an object in an image. The premise is that such a concept is closely related to a user's specific preferences and subjectivity and, thus, allows to deal with the complexity and content-dependency of medical image content. We describe an object in terms of multiple continuous boundary features and represent an object concept by the stochastic characteristics of an object population. A population-based incrementally learning technique, in combination with relevance feedback, is then used for concept customization. The user determines the speed and direction of concept customization using a single parameter that defines the degree of exploration and exploitation of the search space. Images are retrieved from a database in a limited number of steps based upon the customized concept. To demonstrate our method we have performed concept-based image retrieval on a database of 292 digitized X-ray images of cervical vertebrae with a variety of abnormalities. The results show that our method produces precise and accurate results when doing a direct search. In an open-ended search our method efficiently and effectively explores the search space.

Information contained in medical images differs considerably from that residing in alphanumeric format. The difference can be attributed to four characteristics: (1) the semantics of medical knowledge extractable from images is imprecise; (2) image information contains form and spatial data, which are not expressible in conventional language; (3) a large part of image information is geometric; (4) diagnostic inferences derived from images rest on an incomplete, continuously evolving model of normality. This paper explores the differentiating characteristics of text versus images and their impact on design of a medical image database intended to allow content-based indexing and retrieval. One strategy for implementing medical image databases is presented, which employs object-oriented iconic queries, semantics by association with prototypes, and a generic schema.

Medical tomographic images are formed by the intersection of the image plane and an object. As the image plane changes, different parts of the object come in view or drop out of view. However, for small changes of the image plane, most parts continue to remain visible and their qualitative embedding in the image remains similar. Therefore, similarity of part embeddings can be used to infer similarity of image planes. Part embeddings are useful features for other vision applications as well. In view of this, a spatial relation called "arrangement" is proposed to describe part embeddings. The relation describes how each part is surrounded by its neighbors. Further, a metric for arrangements is formulated by expressing arrangements in terms of the Voronoi diagram of the parts. Arrangements and their metric are used to retrieve images by image plane similarity in a cardiac magnetic resonance image database. Experiments with the database are reported which (1) validate the observation that similarity of image planes can be inferred from similarity of part embeddings, and (2) compare the performance of arrangement based image retrieval with that of expert radiologists.>

Careful study of medical informatics research and library-resource projects is necessary to increase the productivity of the research and development enterprise. Medical informatics research projects can present unique problems with respect to evaluation. It is not always possible to adapt directly the evaluation methods that are commonly employed in the natural and social sciences. Problems in evaluating medical informatics projects may be overcome by formulating system development work in terms of a testable hypothesis; subdividing complex projects into modules, each of which can be developed, tested and evaluated rigorously; and utilizing qualitative studies in situations where more definitive quantitative studies are impractical.

A qualitative spatial relation called 'arrangement' is proposed. Given an image, the relation describes the sequence in which neighbors of each part are situated around it. The relation captures a perceptual gestalt of the image. An application of the relation to similarity retrieval in medical image databases is discussed. 'Arrangement' is closely related to directional relations and extends the notion of directional relations to parts that have complex shapes. A metric for comparing 'arrangements' is also proposed. The metric is obtained by interpreting 'arrangements' in terms of Voronoi diagrams. The metric enables robust use of the relation in real-world situations.>

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