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Chris Beecher

dblp:53/4542 · DBLP profile ↗
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1ranked-venue papers
0as first author
0since 2021 · last 2004
—ORCID · unresolved

Domains — the database's venue-derived domains; a paper can count in several

Artificial intelligence and machine learning · 1Databases, data management, data science and information retrieval · 1

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Interdisciplinary, comprehensive, and emerging computing
1 paper
Bioinformatics and computational biology · 100%
Databases, data mining, and information retrieval
1 paper
Data mining · 100%

Topics — the 5 heaviest of 5, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Bioinformatics and computational biology › biomarker discovery
biomarker selection
0.012004
Learning a complex metabolomic dataset using random forests and support vector machines · KDD 2004
Bioinformatics and computational biology
metabolomics
0.012004
Learning a complex metabolomic dataset using random forests and support vector machines · KDD 2004
Data mining › predictive modeling
classification
0.012004
Learning a complex metabolomic dataset using random forests and support vector machines · KDD 2004
Data mining › predictive modeling › classification › ensemble learning
random forest
0.012004
Learning a complex metabolomic dataset using random forests and support vector machines · KDD 2004
Data mining › predictive modeling › classification
support vector machine
0.012004
Learning a complex metabolomic dataset using random forests and support vector machines · KDD 2004

Methods — techniques the papers use, named apart from their topics

variable selection · 0.1support vector machine · 0.1random forest · 0.1outlier detection · 0.1
YearPublicationVenuePosition
2004 Learning a complex metabolomic dataset using random forests and support vector machines
abstract
Metabolomics is the "omics" science of biochemistry. The associated data include the quantitative measurements of all small molecule metabolites in a biological sample. These datasets provide a window into dynamic biochemical networks and conjointly with other "omic" data, genes and proteins, have great potential to unravel complex human diseases. The dataset used in this study has 63 individuals, normal and diseased, and the diseased are drug treated or not, so there are three classes. The goal is to classify these individuals using the observed metabolite levels for 317 measured metabolites. There are a number of statistical challenges: non-normal data, the number of samples is less than the number of metabolites; there are missing data and the fact that data are missing is informative (assay values below detection limits can point to a specific class); also, there are high correlations among the metabolites. We investigate support vector machines (SVM), and random forest (RF), for outlier detection, variable selection and classification. We use the variables selected with RF in SVM and visa versa. The benefit of this study is insight into interplay of variable selection and classification methods. We link our selected predictors to the biochemistry of the disease.
Young Truong, Xiaodong Lin 0004, Chris Beecher
KDD3