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Henning Müller

dblp:93/4446 · DBLP profile ↗
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103ranked-venue papers
12as first author
28since 2021 · last 2026
0000-0001-6800-9878ORCID · verified

Domains — the database's venue-derived domains; a paper can count in several

Graphics, computer vision, multimedia, augmented reality and games · 35 · 9 first-author · 3 since 2021Applied, interdisciplinary, general and emerging computing · 33 · 10 since 2021Databases, data management, data science and information retrieval · 27 · 2 first-author · 12 since 2021Artificial intelligence and machine learning · 22 · 4 first-author · 4 since 2021Human-computer interaction and ubiquitous computing · 4 · 1 since 2021Systems, architecture and hardware · 2 · 1 since 2021Computer networks · 1 · 1 since 2021

Expertise — from the expertise taxonomy: the topics of the expert's papers under the CCF categories. A weight counts papers with recency: 1 for a paper about the topic, 0.3 when the topic is its context, halved every five years.

Databases, data mining, and information retrieval
5 papers
Information retrieval · 87% Web and social media mining · 8% Data mining · 5%
Computer graphics and multimedia
4 papers
Image and video processing · 59% Multimedia analysis and retrieval · 41%
Interdisciplinary, comprehensive, and emerging computing
5 papers
Medical and health informatics · 52% Environmental and earth informatics · 48%
Artificial intelligence
2 papers
Image recognition and object detection · 100%

Topics — the 21 heaviest of 26, each with the papers that count most for it

TopicWeightPapersLastEvidence papers
Information retrieval
retrieval evaluation
0.622021
Benchmarking Image Retrieval Diversification Techniques for Social Media · IEEE Trans. Multim. 2021
Evaluation axes for medical image retrieval systems: the imageCLEF experience · ACM Multimedia 2005
Information retrieval › evaluation
benchmark
0.512021
Benchmarking Image Retrieval Diversification Techniques for Social Media · IEEE Trans. Multim. 2021
Multimedia analysis and retrieval › multimedia retrieval › content-based retrieval
content-based multimedia retrieval
0.312017
Retrieval From and Understanding of Large-Scale Multi-modal Medical Datasets: A Review · IEEE Trans. Multim. 2017
Multimedia analysis and retrieval › image retrieval
medical image retrieval
0.312017
Retrieval From and Understanding of Large-Scale Multi-modal Medical Datasets: A Review · IEEE Trans. Multim. 2017
Image and video processing
texture analysis
0.312017
3D Solid Texture Classification Using Locally-Oriented Wavelet Transforms · IEEE Trans. Image Process. 2017
Image and video processing
wavelet transform
0.312017
3D Solid Texture Classification Using Locally-Oriented Wavelet Transforms · IEEE Trans. Image Process. 2017
Environmental and earth informatics
biodiversity monitoring
0.212016
Crowdsourcing Biodiversity Monitoring: How Sharing your Photo Stream can Sustain our Planet · ACM Multimedia 2016
Information retrieval › document retrieval › domain-specific retrieval
biomedical information retrieval
0.212014
MedIR14: medical information retrieval workshop · SIGIR 2014
Image and video processing › texture analysis
texture classification
0.212014
Rotation-Covariant Texture Learning Using Steerable Riesz Wavelets · IEEE Trans. Image Process. 2014
Information retrieval › image retrieval › web image search
social image retrieval
0.112021
Benchmarking Image Retrieval Diversification Techniques for Social Media · IEEE Trans. Multim. 2021
Web and social media mining
social media analysis
0.112021
Benchmarking Image Retrieval Diversification Techniques for Social Media · IEEE Trans. Multim. 2021
Medical and health informatics › medical imaging
medical image analysis
0.112017
Retrieval From and Understanding of Large-Scale Multi-modal Medical Datasets: A Review · IEEE Trans. Multim. 2017
Information retrieval
query log analysis
0.112016
Crowdsourcing Biodiversity Monitoring: How Sharing your Photo Stream can Sustain our Planet · ACM Multimedia 2016
Medical and health informatics › clinical text processing
clinical information retrieval
0.112014
MedIR14: medical information retrieval workshop · SIGIR 2014
Medical and health informatics › medical imaging › medical image data management
medical image retrieval
0.112005
Evaluation axes for medical image retrieval systems: the imageCLEF experience · ACM Multimedia 2005
Information retrieval
evaluation
0.112005
Evaluation axes for medical image retrieval systems: the imageCLEF experience · ACM Multimedia 2005
Information retrieval
image retrieval
0.012004
Learning from User Behavior in Image Retrieval: Application of Market Basket Analysis · Int. J. Comput. Vis. 2004
Data mining › pattern mining › association rule mining
market basket analysis
0.012004
Learning from User Behavior in Image Retrieval: Application of Market Basket Analysis · Int. J. Comput. Vis. 2004
Data mining
pattern mining
0.012004
Learning from User Behavior in Image Retrieval: Application of Market Basket Analysis · Int. J. Comput. Vis. 2004
Information retrieval
user behavior
0.012004
Learning from User Behavior in Image Retrieval: Application of Market Basket Analysis · Int. J. Comput. Vis. 2004
Multimedia analysis and retrieval › image retrieval
content-based image retrieval
0.012005
Evaluation axes for medical image retrieval systems: the imageCLEF experience · ACM Multimedia 2005

Methods — techniques the papers use, named apart from their topics

crowdsourcing · 0.8computer vision · 0.8hand-crafted features · 0.6deep learning · 0.6multimodal retrieval · 0.5diversity evaluation · 0.5structure tensor · 0.3steerable filterbank · 0.3local alignment · 0.3riesz wavelet transform · 0.2kernel support vector machine · 0.2evaluation axes · 0.2benchmark campaign · 0.2market basket analysis · 0.0
YearPublicationVenuePosition
2026 ImageCLEF 2026: Multimodal Challenges in Medicine, Science, Agritech, and Security
Bogdan Ionescu, Henning Müller, Dan-Cristian Stanciu, Ahmedkhan Radzhabov, Alba Garcia Seco de Herrera, Alexandra-Georgiana Andrei, Alexandra Baicoianu, Ana Neacsu, Andrea M. Storås, Asma Ben Abacha, Benjamin Bracke, Lea Reinartz, Benjamin Lecouteux, Christoph M. Friedrich, Cynthia Sabrina Schmidt, Corneliu Florea, Diandra Fabre, Didier Schwab, Dimitar Dimitrov 0003, Emmanuelle Esperança-Rodier, Mihai Gabriel Constantin, Hendrik Damm, Henning Schäfer, Ivan Koychev, Josiane Mothe, Liviu-Daniel Stefan, Maja J. Hjuler, Mehmet Kurt, Meliha Yetisgen, Michael Riegler 0001, Mihai Dogariu, Mihai Ivanovici, Ming Shan Hee, Mohammad El Sakka, Momina Ahsan, Obioma Pelka, Pål Halvorsen, Preslav Nakov, Raphael Brüngel, Steven Alexander Hicks, Sushant Gautam, Tabea Margareta Grace Pakull, Bahadir Eryilmaz, Vajira Thambawita, Vassili Kovalev, Wen-Wai Yim, Yuri Prokopchuk, Zhuohan Xie
ECIR (4)2
2026 Retrospective Matching Network-Based One-Shot Multi-Object Tracking Method for UAV
abstract
ABSTRACT Multi‐Object Tracking (MOT) is promising for UAV applications but faces challenges such as small targets, occlusions, motion blur, and cluttered backgrounds. This work proposes a one‐shot MOT framework with a retrospective matching architecture for UAV ground tracking. Using FairMOT as the baseline avoids two‐stage redundancy, enhancing UAV deployment efficiency. The lightweight retrospective matching network, comprising feature extraction, sparse graph tracking, and a refinement module, leverages historical information to recover tracking failures, improving continuity and accuracy with low computational cost. Experiments on public benchmarks show superior tracking performance and real‐time efficiency.
Yixiao Tan, Sentao Xu, Manfredo Atzori, Henning Müller
Concurr. Comput. Pract. Exp.6
2026 TransformEEG: Towards improving model generalizability in deep learning-based EEG Parkinson's disease detection
abstract
Electroencephalography (EEG) is establishing itself as an important, low-cost, noninvasive diagnostic tool for the early detection of Parkinson’s Disease (PD). In this context, EEG-based Deep Learning (DL) models have shown promising results due to their ability to discover highly nonlinear patterns within the signal. However, current state-of-the-art DL models suffer from poor generalizability caused by high inter-subject variability. This high variability underscores the need for enhancing model generalizability by developing new architectures better tailored to EEG data. This paper introduces TransformEEG, a hybrid Convolutional-Transformer designed for Parkinson’s disease detection using EEG data. Unlike transformer models based on the EEGNet structure, TransformEEG incorporates a depthwise convolutional tokenizer. This tokenizer is specialized in generating tokens composed by channel-specific features, which enables more effective feature mixing within the self-attention layers of the transformer encoder. To evaluate the proposed model, four public datasets comprising 290 subjects (140 PD patients, 150 healthy controls) were harmonized and aggregated. A 10-outer, 10-inner Nested-Leave-N-Subjects-Out (N-LNSO) cross-validation was performed to provide an unbiased comparison against seven other consolidated EEG deep learning models. TransformEEG achieved the highest balanced accuracy’s median (78.45 %) as well as the lowest interquartile range (6.37 %) across all the N-LNSO partitions. When combined with data augmentation and threshold correction, median accuracy increased to 80.10 %, with an interquartile range of 5.74 %. In conclusion, TransformEEG produces more consistent and less skewed results. It demonstrates a substantial reduction in variability and more reliable PD detection using EEG data compared to the other investigated models. • This work presents TransformEEG, a novel hybrid convolutional-transformer model. • TransformEEG reduces performance variability in Parkinson’s Disease detection. • TransformEEG was evaluated on four public datasets comprising 290 subjects. • Data augmentation further enhance TransformEEG performance. • Classification threshold correction further enhance TransformEEG performance.
Federico Del Pup, Riccardo Brun, Filippo Iotti, Edoardo Paccagnella, Mattia Pezzato, Sabrina Bertozzo, Andrea Zanola, Louis Fabrice Tshimanga, Henning Müller, Manfredo Atzori
Neurocomputing9
2026 Multi-structure segmentation in CBCT volumes: The ToothFairy2 challenge
abstract
Cone-beam computed tomography (CBCT) is widely used for dento-maxillofacial diagnostics and treatment planning, and comprehensive multi-structure segmentation remains time-consuming, limiting large-scale, reproducible research. In this article, we present ToothFairy2, a MICCAI 2024 challenge on multi-structure segmentation in maxillofacial CBCT. The accompanying dataset comprises 530 CBCT volumes (480 public training, 50 hidden test) with expert 3D annotations of 42 classes, including maxilla, mandible, crowns, bridges, implants, inferior alveolar canals, maxillary sinuses, pharynx, and teeth labeled according to the International Tooth Numbering System (FDI). 26 international teams participated in ToothFairy2, and their methods were run and evaluated for voxel-wise multi-class segmentation using a standardized protocol. This report extends the evaluation of teeth to also investigate the current capabilities of tooth detection and FDI numbering. Furthermore, ranking stability was analyzed to assess the robustness of the final challenge outcome. Overall, challenge participants achieved consistently high performance for large, high-contrast structures such as jawbones, pharynx, and most teeth, while maxillary sinuses, dental restorations, and fine structures remain challenging due to class imbalance and metal artifacts. Analysis of tooth-related metrics further revealed that assigning correct FDI numbers was more challenging than delineating individual teeth. By releasing CBCT data, 3D annotations, baseline models, and evaluation code, ToothFairy2 establishes a long-term benchmark to drive the development of automated methods for robust, clinically meaningful multi-structure segmentation in maxillofacial CBCT.
Federico Bolelli, Luca Lumetti, Niels van Nistelrooij, Shankeeth Vinayahalingam, Mattia Di Bartolomeo, Kevin Marchesini, Arrigo Pellacani, Ettore Candeloro, Gabriele Rosati, Tong Xi 0001, Fabian Isensee, Yannick Kirchhoff, Lars Krämer, Maximilian Rokuss, Constantin Ulrich, Klaus H. Maier-Hein, Yuxian Jiang, Yusheng Liu 0001, Lisheng Wang, Haoshen Wang, Zhiming Cui 0001, Zhaohong Pan, Xiaokun Liang, Ender Konukoglu, Marek Wodzinski, Henning Müller, Haipeng Mai, Xiaobing Dang, Shrajan Bhandary, Radu Grosu, Stefaan Bergé, Alexandre Anesi, Costantino Grana
Medical Image Anal.29
2026 Multi-class segmentation of aortic branches and zones in computed tomography angiography: The AortaSeg24 challenge
Muhammad Imran 0013, Jonathan R. Krebs, Vishal Balaji Sivaraman, Amarjeet Kumar, Walker R. Ueland, Michael J. Fassler, Lisheng Wang, Maximilian Rokuss, Michael Baumgartner 0001, Yannick Kirchhof, Klaus H. Maier-Hein, Fabian Isensee, Shuolin Liu, Bong Thanh Nguyen, Dong-jin Shin, Park Ji-Woo, Matthew Choi, Kwang-Hyun Uhm, Sung-Jea Ko, Chanwoong Lee, Jaehee Chun, Yun Gu, Zhaohong Pan, Xiaokun Liang, Markus Tiefenthaler, Enrique Almar-Munoz, Matthias Schwab, Mikhail Kotyushev, Rostislav Epifanov, Marek Wodzinski, Henning Müller, Abdul Qayyum 0002, Moona Mazher, Steven A. Niederer, Zhiwei Wang 0002, Kaixiang Yang 0004, Jintao Ren, Stine Sofia Korreman, Yuchong Gao, Hongye Zeng, Jinghua Yue, Fugen Zhou, Alexander Cosman, Muxuan Liang, Gilbert R. Upchurch Jr., Yuyin Zhou, Michol A. Cooper, Wei Shao 0008
Medical Image Anal.42
2026 BONBID-HIE 2023: Lesion Segmentation Challenge in BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy
abstract
Hypoxic Ischemic Encephalopathy (HIE) represents a brain dysfunction, affecting approximately 1 to 5 per 1000 full-term neonates. The precise delineation and segmentation of HIE-related lesions in neonatal brain Magnetic Resonance Images (MRI) are pivotal in advancing outcome predictions, identifying patients at high risk, elucidating neurological manifestations, and assessing treatment efficacies. Despite its importance, the development of algorithms for segmenting HIE lesions from MRI volumes has been impeded by data scarcity. Addressing this critical gap, we organized the first BONBID-HIE challenge with diffusion MRI data (Apparent Diffusion Coefficient (ADC) maps) for HIE lesion segmentation, in conjunction with the MICCAI 2023. Totally 14 algorithms were submitted, employing a gamut of cutting-edge automatic machine-learning-based segmentation algorithms. Our comprehensive analysis of HIE lesion segmentation and submitted algorithms facilitates an in-depth evaluation of the current technological zenith, outlines directions for future advancements, and highlights persistent hurdles. To foster ongoing research and benchmarking, the annotated HIE dataset, developed algorithm dockers, and unified evaluation codes are accessible through a dedicated online platform (https://bonbid-hie2023.grand-challenge.org).
Rina Bao, Anna N. Foster, Ya'Nan Song, Rutvi Vyas, Ankush Kesri, Imad Eddine Toubal, Elham Soltanikazemi, Gani Rahmon, Taci Kucukpinar, Mohamed Almansour, Mai-Lan Ho, Kannappan Palaniappan, Dean Ninalga, Chiranjeewee Prasad Koirala, Sovesh Mohapatra, Gottfried Schlaug, Marek Wodzinski, Henning Müller, David Gage Ellis, Michele R. Aizenberg, M. Arda Aydin, Elvin Abdinli, Gozde Unal, Nazanin Tahmasebi, Kumaradevan Punithakumar, Tian Song 0001, Sara V. Bates, Randy Hirschtick, Patricia Ellen Grant, Yangming Ou
IEEE Trans. Medical Imaging18
2025 ImageCLEF 2025: Multimedia Retrieval in Medical, Social Media and Content Recommendation Applications
Bogdan Ionescu, Henning Müller, Dan-Cristian Stanciu, Ahmad Idrissi-Yaghir, Ahmedkhan Radzhabov, Alba Garcia Seco de Herrera, Alexandra-Georgiana Andrei, Andrea M. Storås, Asma Ben Abacha, Benjamin Bracke, Benjamin Lecouteux, Benno Stein 0001, Cécile Macaire, Christoph M. Friedrich, Cynthia Sabrina Schmidt, Diandra Fabre, Didier Schwab, Dimitar Dimitrov 0003, Emmanuelle Esperança-Rodier, Mihai Gabriel Constantin, Helmut Becker, Hendrik Damm, Henning Schäfer, Ivan Rodkin, Ivan Koychev, Johannes Kiesel, Johannes Rückert, Josep Malvehy, Liviu-Daniel Stefan, Louise Bloch, Martin Potthast, Maximilian Heinrich, Michael Riegler 0001, Mihai Dogariu, Noel Codella, Pål Halvorsen, Preslav Nakov, Raphael Brüngel, Roberto A. Novoa, Rocktim Jyoti Das, Steven Alexander Hicks, Sushant Gautam, Tabea Margareta Grace Pakull, Vajira Thambawita, Vassili Kovalev, Wen-Wai Yim, Zhuohan Xie
ECIR (5)2
2025 LifeCLEF 2025 Teaser: Challenges on Species Presence Prediction and Identification, and Individual Animal Identification
Alexis Joly, Lukás Picek, Stefan Kahl, Hervé Goëau, Lukás Adam, Christophe Botella, Maximilien Servajean, Diego Marcos, César Leblanc, Théo Larcher, Jiri Matas, Klára Janousková, Vojtech Cermák, Kostas Papafitsoros, Robert Planqué, Willem-Pier Vellinga, Holger Klinck, Tom Denton, Pierre Bonnet, Henning Müller
ECIR (5)20
2025 Privacy preserving histopathological image augmentation with Conditional Generative Adversarial Networks
Alexandra-Georgiana Andrei, Mihai Gabriel Constantin, Mara Graziani, Henning Müller, Bogdan Ionescu
Pattern Recognit. Lett.4
2025 Segmenting the Inferior Alveolar Canal in CBCTs Volumes: The ToothFairy Challenge
abstract
In recent years, several algorithms have been developed for the segmentation of the Inferior Alveolar Canal (IAC) in Cone-Beam Computed Tomography (CBCT) scans. However, the availability of public datasets in this domain is limited, resulting in a lack of comparative evaluation studies on a common benchmark. To address this scientific gap and encourage deep learning research in the field, the ToothFairy challenge was organized within the MICCAI 2023 conference. In this context, a public dataset was released to also serve as a benchmark for future research. The dataset comprises 443 CBCT scans, with voxel-level annotations of the IAC available for 153 of them, making it the largest publicly available dataset of its kind. The participants of the challenge were tasked with developing an algorithm to accurately identify the IAC using the 2D and 3D-annotated scans. This paper presents the details of the challenge and the contributions made by the most promising methods proposed by the participants. It represents the first comprehensive comparative evaluation of IAC segmentation methods on a common benchmark dataset, providing insights into the current state-of-the-art algorithms and outlining future research directions. Furthermore, to ensure reproducibility and promote future developments, an open-source repository that collects the implementations of the best submissions was released.
Federico Bolelli, Luca Lumetti, Shankeeth Vinayahalingam, Mattia Di Bartolomeo, Arrigo Pellacani, Kevin Marchesini, Niels van Nistelrooij, Pieter van Lierop, Tong Xi 0001, Yusheng Liu 0001, Rui Xin 0003, Tao Yang 0037, Lisheng Wang, Haoshen Wang, Chenfan Xu, Zhiming Cui 0001, Marek Wodzinski, Henning Müller, Yannick Kirchhoff, Maximilian Rokuss, Klaus H. Maier-Hein, Jae-Hwan Han, Wan Kim, Hong-Gi Ahn, Tomasz Szczepanski, Michal K. Grzeszczyk, Przemyslaw Korzeniowski, Vicent Caselles, Xavier Paolo Burgos-Artizzu, Ferran Prados, Stefaan Bergé, Bram van Ginneken, Alexandre Anesi, Costantino Grana
IEEE Trans. Medical Imaging18
2025 Introduction to the Special Issue on Realistic Synthetic Data: Generation, Learning, Evaluation
abstract
This is the foreword of our special issue volume on Realistic Synthetic Data: Generation, Learning, Evaluation organized with the ACM Transactions on Multimedia Computing, Communications, and Applications. It presents the target of the special issue that relates to synthetic data for various modalities, e.g., signals, images, volumes, audio, etc., controllable generation for learning from synthetic data, transfer learning and generalization of models, causality in data generation, addressing bias, limitations and trustworthiness in data generation, evaluation measures/protocols and benchmarks to assess quality of synthetic content, open synthetic datasets and software tools, and ethical aspects of synthetic data. The call for papers received a record number of 40 submissions out of which 15 were finally accepted for publication. This introduction provides an overview of the topics of each of the articles.
Bogdan Ionescu, Ioannis Patras, Henning Müller, Alberto Del Bimbo
ACM Trans. Multim. Comput. Commun. Appl.3
2024 The CLEF 2024 Monster Track: One Lab to Rule Them All
Nicola Ferro 0001, Julio Gonzalo 0001, Jussi Karlgren, Henning Müller
ECIR (6)4
2024 Advancing Multimedia Retrieval in Medical, Social Media and Content Recommendation Applications with ImageCLEF 2024
Bogdan Ionescu, Henning Müller, Ana-Maria Claudia Dragulinescu, Ahmad Idrissi-Yaghir, Ahmedkhan Radzhabov, Alba Garcia Seco de Herrera, Alexandra-Georgiana Andrei, Alexandru Stan, Andrea M. Storås, Asma Ben Abacha, Benjamin Lecouteux, Benno Stein 0001, Cécile Macaire, Christoph M. Friedrich, Cynthia Sabrina Schmidt, Didier Schwab, Emmanuelle Esperança-Rodier, George Ioannidis, Griffin Adams, Henning Schäfer, Hugo Manguinhas, Ioan Coman, Johanna Schöler, Johannes Kiesel, Johannes Rückert, Louise Bloch, Martin Potthast, Maximilian Heinrich, Meliha Yetisgen, Michael Riegler 0001, Neal Snider, Pål Halvorsen, Raphael Brüngel, Steven Alexander Hicks, Vajira Thambawita, Vassili Kovalev, Yuri Prokopchuk, Wen-Wai Yim
ECIR (6)2
2024 LifeCLEF 2024 Teaser: Challenges on Species Distribution Prediction and Identification
Alexis Joly, Lukás Picek, Stefan Kahl, Hervé Goëau, Vincent Espitalier, Christophe Botella, Benjamin Deneu, Diego Marcos, Joaquim Estopinan, César Leblanc, Théo Larcher, Milan Sulc, Marek Hrúz, Maximilien Servajean, Jiri Matas, Hervé Glotin, Robert Planqué, Willem-Pier Vellinga, Holger Klinck, Tom Denton, Andrew Durso, Ivan Eggel, Pierre Bonnet, Henning Müller
ECIR (6)24
2024 A systematic comparison of deep learning methods for Gleason grading and scoring
abstract
Prostate cancer is the second most frequent cancer in men worldwide after lung cancer. Its diagnosis is based on the identification of the Gleason score that evaluates the abnormality of cells in glands through the analysis of the different Gleason patterns within tissue samples. The recent advancements in computational pathology, a domain aiming at developing algorithms to automatically analyze digitized histopathology images, lead to a large variety and availability of datasets and algorithms for Gleason grading and scoring. However, there is no clear consensus on which methods are best suited for each problem in relation to the characteristics of data and labels. This paper provides a systematic comparison on nine datasets with state-of-the-art training approaches for deep neural networks (including fully-supervised learning, weakly-supervised learning, semi-supervised learning, Additive-MIL, Attention-Based MIL, Dual-Stream MIL, TransMIL and CLAM) applied to Gleason grading and scoring tasks. The nine datasets are collected from pathology institutes and openly accessible repositories. The results show that the best methods for Gleason grading and Gleason scoring tasks are fully supervised learning and CLAM, respectively, guiding researchers to the best practice to adopt depending on the task to solve and the labels that are available.
Juan Pedro Dominguez-Morales, Lourdes Duran-Lopez, Niccolò Marini, Saturnino Vicente Diaz, Alejandro Linares-Barranco, Manfredo Atzori, Henning Müller
Medical Image Anal.7
2024 Multimodal representations of biomedical knowledge from limited training whole slide images and reports using deep learning
abstract
The increasing availability of biomedical data creates valuable resources for developing new deep learning algorithms to support experts, especially in domains where collecting large volumes of annotated data is not trivial. Biomedical data include several modalities containing complementary information, such as medical images and reports: images are often large and encode low-level information, while reports include a summarized high-level description of the findings identified within data and often only concerning a small part of the image. However, only a few methods allow to effectively link the visual content of images with the textual content of reports, preventing medical specialists from properly benefitting from the recent opportunities offered by deep learning models. This paper introduces a multimodal architecture creating a robust biomedical data representation encoding fine-grained text representations within image embeddings. The architecture aims to tackle data scarcity (combining supervised and self-supervised learning) and to create multimodal biomedical ontologies. The architecture is trained on over 6,000 colon whole slide Images (WSI), paired with the corresponding report, collected from two digital pathology workflows. The evaluation of the multimodal architecture involves three tasks: WSI classification (on data from pathology workflow and from public repositories), multimodal data retrieval, and linking between textual and visual concepts. Noticeably, the latter two tasks are available by architectural design without further training, showing that the multimodal architecture that can be adopted as a backbone to solve peculiar tasks. The multimodal data representation outperforms the unimodal one on the classification of colon WSIs and allows to halve the data needed to reach accurate performance, reducing the computational power required and thus the carbon footprint. The combination of images and reports exploiting self-supervised algorithms allows to mine databases without needing new annotations provided by experts, extracting new information. In particular, the multimodal visual ontology, linking semantic concepts to images, may pave the way to advancements in medicine and biomedical analysis domains, not limited to histopathology.
Niccolò Marini, Stefano Marchesin 0001, Marek Wodzinski, Alessandro Caputo, Damian Podareanu, Bryan Cardenas Guevara, Svetla Boytcheva, Simona Vatrano, Filippo Fraggetta, Francesco Ciompi, Gianmaria Silvello, Henning Müller, Manfredo Atzori
Medical Image Anal.12
2024 The ACROBAT 2022 challenge: Automatic registration of breast cancer tissue
abstract
The alignment of tissue between histopathological whole-slide-images (WSI) is crucial for research and clinical applications. Advances in computing, deep learning, and availability of large WSI datasets have revolutionised WSI analysis. Therefore, the current state-of-the-art in WSI registration is unclear. To address this, we conducted the ACROBAT challenge, based on the largest WSI registration dataset to date, including 4,212 WSIs from 1,152 breast cancer patients. The challenge objective was to align WSIs of tissue that was stained with routine diagnostic immunohistochemistry to its H&E-stained counterpart. We compare the performance of eight WSI registration algorithms, including an investigation of the impact of different WSI properties and clinical covariates. We find that conceptually distinct WSI registration methods can lead to highly accurate registration performances and identify covariates that impact performances across methods. These results provide a comparison of the performance of current WSI registration methods and guide researchers in selecting and developing methods.
Philippe Weitz, Masi Valkonen, Leslie Solorzano, Circe Carr, Kimmo Kartasalo, Constance Boissin, Sonja Koivukoski, Aino Kuusela, Dusan Rasic, Yanbo Feng, Sandra Kristiane Sinius Pouplier, Kajsa Ledesma Eriksson, Stephanie Robertson, Christian Marzahl, Chandler Gatenbee, Alexander R. A. Anderson, Marek Wodzinski, Artur Jurgas, Niccolò Marini, Manfredo Atzori, Henning Müller, Daniel Budelmann, Nick Weiss, Stefan Heldmann, Johannes Lotz 0002, Jelmer M. Wolterink, Bruno De Santi, Abhijeet Patil, Amit Sethi, Satoshi Kondo, Satoshi Kasai, Kousuke Hirasawa, Mahtab Farrokh, Neeraj Kumar 0002, Russell Greiner, Leena Latonen, Anne-Vibeke Laenkholm, Johan Hartman, Pekka Ruusuvuori, Mattias Rantalainen
Medical Image Anal.22
2023 ImageCLEF 2023 Highlight: Multimedia Retrieval in Medical, Social Media and Content Recommendation Applications
Bogdan Ionescu, Henning Müller, Ana-Maria Claudia Dragulinescu, Adrian Popescu 0001, Ahmad Idrissi-Yaghir, Alba Garcia Seco de Herrera, Alexandra-Georgiana Andrei, Alexandru Stan, Andrea M. Storås, Asma Ben Abacha, Christoph M. Friedrich, George Ioannidis, Griffin Adams, Henning Schäfer, Hugo Manguinhas, Ihar Filipovich, Ioan Coman, Jérôme Deshayes-Chossart, Johanna Schöler, Johannes Rückert, Liviu-Daniel Stefan, Louise Bloch, Meliha Yetisgen, Michael Riegler 0001, Mihai Dogariu, Mihai Gabriel Constantin, Neal Snider, Nikolaos Papachrysos, Pål Halvorsen, Raphael Brüngel, Serge Kozlovski, Steven Alexander Hicks, Thomas de Lange, Vajira Thambawita, Vassili Kovalev, Wen-Wai Yim
ECIR (3)2
2023 LifeCLEF 2023 Teaser: Species Identification and Prediction Challenges
Alexis Joly, Hervé Goëau, Stefan Kahl, Lukás Picek, Christophe Botella, Diego Marcos, Milan Sulc, Marek Hrúz, Titouan Lorieul, Sara Si-Moussi, Maximilien Servajean, Benjamin Kellenberger, Elijah Cole, Andrew Durso, Hervé Glotin, Robert Planqué, Willem-Pier Vellinga, Holger Klinck, Tom Denton, Ivan Eggel, Pierre Bonnet, Henning Müller
ECIR (3)22
2023 A novel Siamese deep hashing model for histopathology image retrieval
Seyed Mohammad Alizadeh, Mohammad Sadegh Helfroush, Henning Müller
Expert Syst. Appl.3
2022 ImageCLEF 2022: Multimedia Retrieval in Medical, Nature, Fusion, and Internet Applications
Alba Garcia Seco de Herrera, Bogdan Ionescu, Henning Müller, Renaud Péteri, Asma Ben Abacha, Christoph M. Friedrich, Johannes Rückert, Louise Bloch, Raphael Brüngel, Ahmad Idrissi-Yaghir, Henning Schäfer, Serge Kozlovski, Yashin Dicente Cid, Vassili Kovalev, Jon Chamberlain, Adrian F. Clark, Antonio C. de A. Campello Jr., Hugo Schindler, Jérôme Deshayes-Chossart, Adrian Popescu 0001, Liviu-Daniel Stefan, Mihai Gabriel Constantin, Mihai Dogariu
ECIR (2)3
2022 LifeCLEF 2022 Teaser: An Evaluation of Machine-Learning Based Species Identification and Species Distribution Prediction
Alexis Joly, Hervé Goëau, Stefan Kahl, Lukás Picek, Titouan Lorieul, Elijah Cole, Benjamin Deneu, Maximilien Servajean, Andrew Durso, Isabelle Bolon, Hervé Glotin, Robert Planqué, Willem-Pier Vellinga, Holger Klinck, Tom Denton, Ivan Eggel, Pierre Bonnet, Henning Müller, Milan Sulc
ECIR (2)18
2021 An End-to-End 3D ConvLSTM-based Framework for Early Diagnosis of Alzheimer's Disease from Full-Resolution Whole-Brain sMRI Scans
abstract
Alzheimer's Disease (AD) is the most prevailing form of dementia, killing more people than prostate and breast cancers combined. Structural Magnetic Resonance Imaging (sMRI) is widely used for the analysis of progressive brain aggravation and its clinical utility in discriminating AD is well established. Even if an effective cure does not exist yet, early detection is fundamental for slowing down the worsening of symptoms. Thus, the aim of the present work is to propose an end-to-end 3D Convolutional Long Short-Term Memory (ConvLSTM)-based framework for early diagnosis of AD from full-resolution whole-brain sMRI scans. The proposed framework was applied to 427 full-resolution whole-brain sMRI scans belonging to both OASIS and ADNI databases in order to provide a less dataset-specific approach. Results show that our framework is performing well in discriminating AD from Cognitively Normal (CN) patients, reaching a classification accuracy of 86%, sensitivity of 96%, f1-score of 88% and AUC of 93% on the test data. The tests were performed on a scalable GPU cloud service and are publicly available to guarantee reproducibility. Since the proposed framework performs well without domain-specific knowledge from AD as well as computationally-costly processes such as segmentation, it can be applied to other mental disorders using whole-brain sMRI scans as input data.
Selene Tomassini, Nicola Falcionelli, Paolo Sernani, Henning Müller, Aldo Franco Dragoni
CBMS4
2021 The 2021 ImageCLEF Benchmark: Multimedia Retrieval in Medical, Nature, Internet and Social Media Applications
Bogdan Ionescu, Henning Müller, Renaud Péteri, Asma Ben Abacha, Dina Demner-Fushman, Sadid A. Hasan, Mourad Sarrouti, Obioma Pelka, Christoph M. Friedrich, Alba Garcia Seco de Herrera, Janadhip Jacutprakart, Vassili Kovalev, Serge Kozlovski, Vitali Liauchuk, Yashin Dicente Cid, Jon Chamberlain, Adrian F. Clark, Antonio C. de A. Campello Jr., Hassan Moustahfid, Thomas Oliver, Abigail Schulz, Paul Brie, Raul Berari, Dimitri Fichou, Andrei Tauteanu, Mihai Dogariu, Liviu-Daniel Stefan, Mihai Gabriel Constantin, Jérôme Deshayes-Chossart, Adrian Popescu 0001
ECIR (2)2
2021 LifeCLEF 2021 Teaser: Biodiversity Identification and Prediction Challenges
Alexis Joly, Hervé Goëau, Elijah Cole, Stefan Kahl, Lukás Picek, Hervé Glotin, Benjamin Deneu, Maximilien Servajean, Titouan Lorieul, Willem-Pier Vellinga, Pierre Bonnet, Andrew Durso, Rafael Luis Ruiz De Castaneda, Ivan Eggel, Henning Müller
ECIR (2)15
2021 Sharpening Local Interpretable Model-Agnostic Explanations for Histopathology: Improved Understandability and Reliability
Mara Graziani, Iam Palatnik de Sousa, Marley M. B. R. Vellasco, Eduardo Costa da Silva, Henning Müller, Vincent Andrearczyk
MICCAI (3)5
2021 Semi-supervised training of deep convolutional neural networks with heterogeneous data and few local annotations: An experiment on prostate histopathology image classification
abstract
Convolutional neural networks (CNNs) are state-of-the-art computer vision techniques for various tasks, particularly for image classification. However, there are domains where the training of classification models that generalize on several datasets is still an open challenge because of the highly heterogeneous data and the lack of large datasets with local annotations of the regions of interest, such as histopathology image analysis. Histopathology concerns the microscopic analysis of tissue specimens processed in glass slides to identify diseases such as cancer. Digital pathology concerns the acquisition, management and automatic analysis of digitized histopathology images that are large, having in the order of 100′0002 pixels per image. Digital histopathology images are highly heterogeneous due to the variability of the image acquisition procedures. Creating locally labeled regions (required for the training) is time-consuming and often expensive in the medical field, as physicians usually have to annotate the data. Despite the advances in deep learning, leveraging strongly and weakly annotated datasets to train classification models is still an unsolved problem, mainly when data are very heterogeneous. Large amounts of data are needed to create models that generalize well. This paper presents a novel approach to train CNNs that generalize to heterogeneous datasets originating from various sources and without local annotations. The data analysis pipeline targets Gleason grading on prostate images and includes two models in sequence, following a teacher/student training paradigm. The teacher model (a high-capacity neural network) automatically annotates a set of pseudo-labeled patches used to train the student model (a smaller network). The two models are trained with two different teacher/student approaches: semi-supervised learning and semi-weekly supervised learning. For each of the two approaches, three student training variants are presented. The baseline is provided by training the student model only with the strongly annotated data. Classification performance is evaluated on the student model at the patch level (using the local annotations of the Tissue Micro-Arrays Zurich dataset) and at the global level (using the TCGA-PRAD, The Cancer Genome Atlas-PRostate ADenocarcinoma, whole slide image Gleason score). The teacher/student paradigm allows the models to better generalize on both datasets, despite the inter-dataset heterogeneity and the small number of local annotations used. The classification performance is improved both at the patch-level (up to κ=0.6127±0.0133 from κ=0.5667±0.0285), at the TMA core-level (Gleason score) (up to κ=0.7645±0.0231 from κ=0.7186±0.0306) and at the WSI-level (Gleason score) (up to κ=0.4529±0.0512 from κ=0.2293±0.1350). The results show that with the teacher/student paradigm, it is possible to train models that generalize on datasets from entirely different sources, despite the inter-dataset heterogeneity and the lack of large datasets with local annotations.
Niccolò Marini, Juan Sebastian Otálora Montenegro, Henning Müller, Manfredo Atzori
Medical Image Anal.3
2021 Benchmarking Image Retrieval Diversification Techniques for Social Media
abstract
Image retrieval has been an active research domain for over 30 years and historically it has focused primarily on precision as an evaluation criterion. Similar to text retrieval, where the number of indexed documents became large and many relevant documents exist, it is of high importance to highlight diversity in the search results to provide better results for the user. The Retrieving Diverse Social Images Task of the MediaEval benchmarking campaign has addressed exactly this challenge of retrieving diverse and relevant results for the past years, specifically in the social media context. Multimodal data (e.g., images, text) was made available to the participants including metadata assigned to the images, user IDs, and precomputed visual and text descriptors. Many teams have participated in the task over the years. The large number of publications employing the data and also citations of the overview articles underline the importance of this topic. In this paper, we introduce these publicly available data resources as well as the evaluation framework, and provide an in-depth analysis of the crucial aspects of social image search diversification, such as the capabilities and the evolution of existing systems. These evaluation resources will help researchers for the coming years in analyzing aspects of multimodal image retrieval and diversity of the search results.
Bogdan Ionescu, Maia Rohm, Bogdan Boteanu, Alexandru-Lucian Gînsca, Mihai Lupu, Henning Müller
IEEE Trans. Multim.6
2020 ImageCLEF 2020: Multimedia Retrieval in Lifelogging, Medical, Nature, and Internet Applications
Bogdan Ionescu, Henning Müller, Renaud Péteri, Duc-Tien Dang-Nguyen, Liting Zhou, Luca Piras 0001, Michael Riegler 0001, Pål Halvorsen, Minh-Triet Tran, Mathias Lux, Cathal Gurrin, Jon Chamberlain, Adrian F. Clark, Antonio C. de A. Campello Jr., Alba Garcia Seco de Herrera, Asma Ben Abacha, Vivek V. Datla, Sadid A. Hasan, Joey Liu, Dina Demner-Fushman, Obioma Pelka, Christoph M. Friedrich, Yashin Dicente Cid, Serge Kozlovski, Vitali Liauchuk, Vassili Kovalev, Raul Berari, Paul Brie, Dimitri Fichou, Mihai Dogariu, Liviu-Daniel Stefan, Mihai Gabriel Constantin
ECIR (2)2
2020 LifeCLEF 2020 Teaser: Biodiversity Identification and Prediction Challenges
Alexis Joly, Hervé Goëau, Stefan Kahl, Christophe Botella, Rafael Luis Ruiz De Castaneda, Hervé Glotin, Elijah Cole, Julien Champ, Benjamin Deneu, Maximilien Servajean, Titouan Lorieul, Willem-Pier Vellinga, Fabian-Robert Stöter, Andrew Durso, Pierre Bonnet, Henning Müller
ECIR (2)16
2020 Multimodal Latent Semantic Alignment for Automated Prostate Tissue Classification and Retrieval
Juan S. Lara, Victor H. Contreras O., Juan Sebastian Otálora Montenegro, Henning Müller, Fabio A. González 0001
MICCAI (5)4
2020 Medical Image Retrieval: Applications and Resources
abstract
Motivation: Medical imaging is one of the largest data producers in the world and over the last 30 years this production increased exponentially via a larger number of images and a higher resolution, plus totally new types of images. Most images are used only in the context of a single patient and a single time point, besides a few images that are used for publications or in teaching. Data are usually scattered across many institutions and cannot be combined even for the treatment of a single patient. Much knowledge is stored in these medical archives of images and other clinical information and content-based medical image retrieval has from the start aimed at making such knowledge accessible using visual information in combination with text or structured data. With the digitization of radiology that started in the mid 1990s the foundation for broader use was laid out. Problem statement: This keynote presentation aims at giving a historical perspective of how medical image retrieval has evolved from a few prototypes using first only text, then global visual features to the current multimodal systems that can index many types of images in large quantities and use deep learning as a basis for the tools [1,2,3,4]. It also aims at looking at what the place of image retrieval is in medicine, where it is currently still only sparsely used in clinical practice. It seems that it is mainly a tool for teaching and research. Certified medical tools for decision support rather make use of specific approaches for detection and classification. Approach: The presentation follows a systematic review of the domain that includes many examples of systems and approaches that changed over time when better performing tools became available. Medical mage retrieval has evolved strongly, and many tools linked to mage retrieval are now employed as clinical decision support but mainly for detection and classification. Retrieval remains useful but is often integrated with tools and thus has become almost invisible. A second aspect of the presentation includes a presentations of existing data sets and other resources that were difficult to obtain even ten years ago, but that have been shared via repositories such as TCGA (The Cancer Genome Atlas, https://www.cancer.gov/about-nci/organization/ccg/ research/structural-genomics/tcga), TCIA (The Cancer Imaging Archive, https://www.cancerimagingarchive.net), or via scientific challenges such ImageCLEF [5] or listed in the Grand Challenges web page (https://grand-challenge.org). Medical data are now easily accessible in many fields and often even in large quantities. Discussion: Medical retrieval has gone from single text or image retrieval to multimodal approaches [6], really aiming to use all data available for a case, similar to what a physician would do by looking at a patient holistically. The limiting factor in terms of data access is now rather linked to limited manual annotations, as the time of clinicians for annotations is expensive. Global labels for images usually exist with the associated text reports that describe images and outcomes. Still, these weak labels need to be made usable with deep learning approaches that possibly require large amounts of data to generalize well. Conclusions: Medical image retrieval has evolved strongly over the past 30 years and can be integrated with several tools. For real clinical decision support, it is still rarely used, also because the certification process is tedious and commercial benefit is not as easy to show, as with detection or classification in a clear and limited scenario. In terms of research many resources are available that allow advances also in the future. Still, certification and ethical aspects also need to be taken into account to limit risks for individuals.
Henning Müller
ICMR1
2020 Studying Public Medical Images from the Open Access Literature and Social Networks for Model Training and Knowledge Extraction
Henning Müller, Vincent Andrearczyk, Oscar Alfonso Jiménez del Toro, Anjani Dhrangadhariya, Roger Schaer, Manfredo Atzori
MMM (2)1
2020 BIAS: Transparent reporting of biomedical image analysis challenges
abstract
The number of biomedical image analysis challenges organized per year is steadily increasing. These international competitions have the purpose of benchmarking algorithms on common data sets, typically to identify the best method for a given problem. Recent research, however, revealed that common practice related to challenge reporting does not allow for adequate interpretation and reproducibility of results. To address the discrepancy between the impact of challenges and the quality (control), the Biomedical Image Analysis ChallengeS (BIAS) initiative developed a set of recommendations for the reporting of challenges. The BIAS statement aims to improve the transparency of the reporting of a biomedical image analysis challenge regardless of field of application, image modality or task category assessed. This article describes how the BIAS statement was developed and presents a checklist which authors of biomedical image analysis challenges are encouraged to include in their submission when giving a paper on a challenge into review. The purpose of the checklist is to standardize and facilitate the review process and raise interpretability and reproducibility of challenge results by making relevant information explicit.
Lena Maier-Hein, Annika Reinke, Michal Kozubek 0001, Anne L. Martel, Tal Arbel, Matthias Eisenmann, Allan Hanbury, Pierre Jannin, Henning Müller, Sinan Onogur, Julio Saez-Rodriguez, Bram van Ginneken, Annette Kopp-Schneider, Bennett A. Landman
Medical Image Anal.9
2020 Guest Editorial: Information Fusion for Medical Data: Early, Late, and Deep Fusion Methods for Multimodal Data
abstract
The papers in this special section examine important current topics on multimodal data fusion in the medical context. All clinical data, including genomic and proteomic, play a role in the diagnosis and in particular in the treatment planning and follow-up. This is true for all types of data analyses whether in classification, regression, retrieval, clustering, or other. The interaction between several types of information is not always well understood. Experienced clinicians automatically and even unconsciously add multiple sources of information into their decision process, but machine learning tools often concentrate on single information sources. This special issue presents five examples where several data sources are fused. The papers give several examples of fusion techniques and also the results obtained in quite different application scenarios.
Inês Domingues, Henning Müller, Andrés Ortiz 0001, Belur V. Dasarathy, Pedro H. Abreu, Vince D. Calhoun
IEEE J. Biomed. Health Informatics2
2019 ImageCLEF 2019: Multimedia Retrieval in Lifelogging, Medical, Nature, and Security Applications
Bogdan Ionescu, Henning Müller, Renaud Péteri, Duc-Tien Dang-Nguyen, Luca Piras 0001, Michael Riegler 0001, Minh-Triet Tran, Mathias Lux, Cathal Gurrin, Yashin Dicente Cid, Vitali Liauchuk, Vassili Kovalev, Asma Ben Abacha, Sadid A. Hasan, Vivek V. Datla, Joey Liu, Dina Demner-Fushman, Obioma Pelka, Christoph M. Friedrich, Jon Chamberlain, Adrian F. Clark, Alba Garcia Seco de Herrera, Narciso García, Ergina Kavallieratou, Carlos R. del-Blanco, Carlos Cuevas, Nikos Vasilopoulos, Konstantinos Karampidis
ECIR (2)2
2019 LifeCLEF 2019: Biodiversity Identification and Prediction Challenges
Alexis Joly, Hervé Goëau, Christophe Botella, Stefan Kahl, Marion Poupard, Maximilien Servajean, Hervé Glotin, Pierre Bonnet, Willem-Pier Vellinga, Robert Planqué, Jan Schlüter, Fabian-Robert Stöter, Henning Müller
ECIR (2)13
2019 Late fusion of deep learning and handcrafted visual features for biomedical image modality classification
abstract
Much of medical knowledge is stored in the biomedical literature, collected in archives like PubMed Central that continue to grow rapidly. A significant part of this knowledge is contained in images with limited metadata available which makes it difficult to explore the visual knowledge in the biomedical literature. Thus, extraction of metadata from visual content is important. One important piece of metadata is the type of the image, which could be one of the various medical imaging modalities such as X‐ray, computed tomography or magnetic resonance images and also of general graphs that are frequent in the literature. This study explores a late, score‐based fusion of several deep convolutional neural networks with a traditional hand‐crafted bag of visual words classifier to classify images from the biomedical literature into image types or modalities. It achieved a classification accuracy of 85.51% on the ImageCLEF 2013 modality classification task, which is better than the best visual methods in the challenge that the data were produced for, and similar compared to mixed methods that make use of both visual and textual information. It achieved similarly good results of 84.23 and 87.04% classification accuracy before and after augmentation, respectively, on the related ImageCLEF 2016 subfigure classification task.
Sheng Long Lee, Mohammad Reza Zare, Henning Müller
IET Image Process.3
2019 Fusing learned representations from Riesz Filters and Deep CNN for lung tissue classification
Ranveer Joyseeree, Juan Sebastian Otálora Montenegro, Henning Müller, Adrien Depeursinge
Medical Image Anal.3
2018 Distributed Container-Based Evaluation Platform for Private/Large Datasets
abstract
The rise of big data and artificial intelligence techniques such as deep learning has lead to an exponential increase in stored data in various fields, including medical imaging, genetics and financial trading. Sharing these increasing amounts of data for research is challenging, as privacy risks increase with the increased size of data. Physically moving very large datasets to researchers is inconvenient, as download or sending physical hard disks are not optimal. Research on sensitive data is often not possible, as sharing is not legal. The popularity of container-based technologies such as Docker has revolutionized the way applications are deployed, due to their self-sufficient, light-weight and portable nature. In this paper, we propose a novel distributed platform using containers for simple execution and evaluation of research applications on the data owner's infrastructure, bringing the algorithms to the data. This approach avoids the cumbersome transfer of large datasets and can help circumventing problems linked to non-shareable data by providing a sandboxed execution environment with read-only access to the data. At no point the data leave the data owner's site, giving researchers access to their evaluation results, only, and not the data themselves. The presented proof-of-concept confirms the feasibility of a distributed container-based evaluation platform for large and/or sensitive data. This has several advantages, including execution of code instead of submission of result files and availability of otherwise inaccessible data. The container architecture allows for minimal computational overhead, no software dependency management on the infrastructure, distributed runtime environment and isolation of processes from the underlying host system. A version addressing various identified architectural and security-related challenges has the potential to be deployed in a production setting and therefore allows researchers to gain insights from previously inaccessible data. One goal is to target hospitals with increasingly strong local infrastructure for storage and computation, needed for artificial intelligence based decision support (genetics and imaging).
Ivan Eggel, Roger Schaer, Henning Müller
ISPDC3
2018 From Local to Global: A Holistic Lung Graph Model
Yashin Dicente Cid, Oscar Alfonso Jiménez del Toro, Alexandra Platon, Henning Müller, Pierre-Alexandre Poletti
MICCAI (2)4
2018 How to Exploit Weaknesses in Biomedical Challenge Design and Organization
Annika Reinke, Matthias Eisenmann, Sinan Onogur, Marko Stankovic 0002, Patrick Godau, Peter M. Full, Hrvoje Bogunovic, Bennett A. Landman, Oskar Maier, Bjoern Menze, Gregory C. Sharp, Korsuk Sirinukunwattana, Stefanie Speidel, Fons van der Sommen, Guoyan Zheng, Henning Müller, Michal Kozubek 0001, Tal Arbel, Andrew P. Bradley, Pierre Jannin, Annette Kopp-Schneider, Lena Maier-Hein
MICCAI (4)16
2018 Subdiv17: a dataset for investigating subjectivity in the visual diversification of image search results
abstract
In this paper, we present a new dataset that facilitates the comparison of approaches aiming at the diversification of image search results. The dataset was explicitly designed for general-purpose, multi-topic queries and provides multiple ground truth annotations to allow for the exploration of the subjectivity aspect in the general task of diversification. The dataset provides images and their metadata retrieved from Flickr for around 200 complex queries. Additionally, to encourage experimentations (and cooperations) from different communities such as information and multimedia retrieval, a broad range of pre-computed descriptors is provided. The proposed dataset was successfully validated during the MediaEval 2017 Retrieving Diverse Social Images task using 29 submitted runs.
Maia Rohm, Bogdan Ionescu, Alexandru-Lucian Gînsca, Rodrygo L. T. Santos, Henning Müller
MMSys5
2018 Large-scale retrieval for medical image analytics: A comprehensive review
Zhongyu Li 0002, Xiaofan Zhang 0002, Henning Müller, Shaoting Zhang 0001
Medical Image Anal.3
2017 Semi-automatic Training of an Object Recognition System in Scene Camera Data Using Gaze Tracking and Accelerometers
Matteo Cognolato, Mara Graziani, Francesca Giordaniello, Gianluca Saetta, Franco Bassetto, Peter C. Brugger, Barbara Caputo, Henning Müller, Manfredo Atzori
ICVS8
2017 Shangri-La: A medical case-based retrieval tool
abstract
Large amounts of medical visual data are produced in hospitals daily and made available continuously via publications in the scientific literature, representing the medical knowledge. However, it is not always easy to find the desired information and in clinical routine the time to fulfil an information need is often very limited. Information retrieval systems are a useful tool to provide access to these documents/images in the biomedical literature related to information needs of medical professionals. Shangri–La is a medical retrieval system that can potentially help clinicians to make decisions on difficult cases. It retrieves articles from the biomedical literature when querying a case description and attached images. The system is based on a multimodal retrieval approach with a focus on the integration of visual information connected to text. The approach includes a query–adaptive multimodal fusion criterion that analyses if visual features are suitable to be fused with text for the retrieval. Furthermore, image modality information is integrated in the retrieval step. The approach is evaluated using the ImageCLEFmed 2013 medical retrieval benchmark and can thus be compared to other approaches. Results show that the final approach outperforms the best multimodal approach submitted to ImageCLEFmed 2013.
Alba Garcia Seco de Herrera, Roger Schaer, Henning Müller
J. Assoc. Inf. Sci. Technol.3
2017 3D Solid Texture Classification Using Locally-Oriented Wavelet Transforms
abstract
Many image acquisition techniques used in biomedical imaging, material analysis, and structural geology are capable of acquiring 3-D solid images. Computational analysis of these images is complex but necessary since it is difficult for humans to visualize and quantify their detailed 3-D content. One of the most common methods to analyze 3-D data is to characterize the volumetric texture patterns. Texture analysis generally consists of encoding the local organization of image scales and directions, which can be extremely diverse in 3-D. Current state-of-the- art techniques face many challenges when working with 3-D solid texture, where most approaches are not able to consistently characterize both scale and directional information. 3-D Riesz- wavelets can deal with both properties. One key property of Riesz filterbanks is steerability, which can be used to locally align the filters and compare textures with arbitrary (local) orientations. This paper proposes and compares three novel local alignment criteria for higher-order 3-D Riesz-wavelet transforms. The estimations of local texture orientations are based on higher- order extensions of regularized structure tensors. An experimental evaluation of the proposed methods for the classification of synthetic 3-D solid textures with alterations (such as rotations and noise) demonstrated the importance of local directional information for robust and accurate solid texture recognition. These alignment methods improved the accuracy of the unaligned Riesz descriptors up to 0.63, from 0.32 to 0.95 over 1 in the rotated data, which is better than all other techniques that are published and tested on the same database.
Yashin Dicente Cid, Henning Müller, Alexandra Platon, Pierre-Alexandre Poletti, Adrien Depeursinge
IEEE Trans. Image Process.2
2017 Retrieval From and Understanding of Large-Scale Multi-modal Medical Datasets: A Review
abstract
Content-based multimedia retrieval (CBMR) has been an active research domain since the mid 1990s. In medicine visual retrieval started later and has mostly remained a research instrument and less a clinical tool. The limited size of data sets due to privacy constraints is often mentioned as reason for these limitations. Nevertheless, much work has been done in CBMR, including the availability of increasingly large data sets and scientific challenges. Annotated data sets and clinical data for images have now become available and can be combined for multi-modal retrieval. Much has been learned on user behavior and application scenarios. This text is motivated by the advances in medical image analysis and the availability of public large data sets that often include clinical data. It is a systematic review of recent work (concentrating on the period 2011-2017) on multi-modal CBMR and image understanding in the medical domain, where image understanding includes techniques such as detection, localization, and classification for leveraging visual content. With the objective of summarizing the current state of research for multimedia researchers outside the medical field, the text provides ways to get data sets and identifies current limitations and promising research directions. The text highlights advances in the past six years and a trend to use larger scale training data and deep learning approaches that can replace/complement hand-crafted features. Using images alone will likely only work in limited domains but combining multiple sources of data for multi-modal retrieval has the biggest chances of success, particularly for clinical impact.
Henning Müller, Devrim Ünay
IEEE Trans. Multim.1
2016 ChaLearn Joint Contest on Multimedia Challenges Beyond Visual Analysis: An overview
abstract
This paper provides an overview of the Joint Contest on Multimedia Challenges Beyond Visual Analysis. We organized an academic competition that focused on four problems that require effective processing of multimodal information in order to be solved. Two tracks were devoted to gesture spotting and recognition from RGB-D video, two fundamental problems for human computer interaction. Another track was devoted to a second round of the first impressions challenge of which the goal was to develop methods to recognize personality traits from short video clips. For this second round we adopted a novel collaborative-competitive (i.e., coopetition) setting. The fourth track was dedicated to the problem of video recommendation for improving user experience. The challenge was open for about 45 days, and received outstanding participation: almost 200 participants registered to the contest, and 20 teams sent predictions in the final stage. The main goals of the challenge were fulfilled: the state of the art was advanced considerably in the four tracks, with novel solutions to the proposed problems (mostly relying on deep learning). However, further research is still required. The data of the four tracks will be available to allow researchers to keep making progress in the four tracks.
Hugo Jair Escalante, Víctor Ponce-López, Jun Wan 0001, Michael Riegler 0001, Albert Clapés, Sergio Escalera, Isabelle Guyon, Xavier Baró, Pål Halvorsen, Henning Müller, Martha A. Larson
ICPR11
2016 Crowdsourcing Biodiversity Monitoring: How Sharing your Photo Stream can Sustain our Planet
abstract
Large scale biodiversity monitoring is essential for sustainable development (earth stewardship). With the recent advances in computer vision, we see the emergence of more and more effective identification tools allowing to set-up large-scale data collection platforms such as the popular [email protected] initiative that allow to reuse interaction data. Although it covers only a fraction of the world flora, this platform is already being used by more than 300K people who produce tens of thousands of validated plant observations each year. This explicitly shared and validated data is only the tip of the iceberg. The real potential relies on the millions of raw image queries submitted by the users of the mobile application for which there is no human validation. People make such requests to get information on a plant along a hike or something they find in their garden but not know anything about. Allowing the exploitation of such contents in a fully automatic way could scale up the world-wide collection of implicit plant observations by several orders of magnitude, which can complement the explicit monitoring efforts. In this paper, we first survey existing automated plant identification systems through a five-year synthesis of the PlantCLEF benchmark and an impact study of the [email protected] platform. We then focus on the implicit monitoring scenario and discuss related research challenges at the frontier of computer science and biodiversity studies. Finally, we discuss the results of a preliminary study focused on implicit monitoring of invasive species in mobile search logs. We show that the results are promising but that there is room for improvement before being able to automatically share implicit observations within international platforms.
Alexis Joly, Hervé Goëau, Julien Champ, Samuel Dufour-Kowalski, Henning Müller, Pierre Bonnet
ACM Multimedia5
2016 Div150Multi: a social image retrieval result diversification dataset with multi-topic queries
abstract
In this paper we introduce a new dataset, Div150Multi, that was designed to support shared evaluation of diversification techniques in different areas of social media photo retrieval and related areas. The dataset comes with associated relevance and diversity assessments performed by trusted annotators. The data consists of around 300 complex queries represented via 86,769 Flickr photos, around 27M photo links for around 6,000 users, metadata, Wikipedia pages and content descriptors for text and visual modalities, including state of the art deep features. To facilitate distribution, only Creative Commons content allowing redistribution was included in the dataset. The proposed dataset was validated during the 2015 Retrieving Diverse Social Images Task at the MediaEval Benchmarking.
Bogdan Ionescu, Alexandru-Lucian Gînsca, Bogdan Boteanu, Mihai Lupu, Adrian Popescu 0001, Henning Müller
MMSys6
2016 GPU-Accelerated Texture Analysis Using Steerable Riesz Wavelets
abstract
Visual pattern recognition is a key research topic in the field of image processing and computer vision. Texture analysis based on steerable Riesz wavelets is powerful, but requires computing pixel-wise operations resulting in a run time in the order of days when large volumes of data are processed. To overcome this limitation we propose a Graphics Processing Unit (GPU) based solution. A standard CPU version is used as starting point for the development of baseline GPU versions. To further increase the performance, and to overcome compute and memory limitations we apply a series of optimization techniques, leading to five versions in total. The best performing GPU solution ensures a speed-up of 93× for the parallelized section of the application and of 29.6× for the entire application. Furthermore, we show that a higher Riesz order and/or a higher image resolution further increases the speed-up.
Anamaria Vizitiu, Lucian Mihai Itu, Ranveer Joyseeree, Adrien Depeursinge, Henning Müller, Constantin Suciu
PDP5
2016 Medical Information Search Workshop (MEDIR)
abstract
No abstract available.
Steven Bedrick, Lorraine Goeuriot, Gareth J. F. Jones, Anastasia Krithara, Henning Müller, Georgios Paliouras
SIGIR5
2016 Medical image modality classification using discrete Bayesian networks
Jacinto Arias, Jesus Martínez-Gómez, José A. Gámez 0001, Alba Garcia Seco de Herrera, Henning Müller
Comput. Vis. Image Underst.5
2016 Medical information retrieval: introduction to the special issue
Lorraine Goeuriot, Gareth J. F. Jones, Liadh Kelly, Henning Müller, Justin Zobel
Inf. Retr. J.4
2016 Evaluating multimodal relevance feedback techniques for medical image retrieval
abstract
Medical image retrieval can assist physicians in finding information supporting their diagnosis and fulfilling information needs. Systems that allow searching for medical images need to provide tools for quick and easy navigation and query refinement as the time available for information search is often short. Relevance feedback is a powerful tool in information retrieval. This study evaluates relevance feedback techniques with regard to the content they use. A novel relevance feedback technique that uses both text and visual information of the results is proposed. The two information modalities from the image examples are fused either at the feature level using the Rocchio algorithm or at the query list fusion step using a common late fusion rule. Results using the ImageCLEF 2012 benchmark database for medical image retrieval show the potential of relevance feedback techniques in medical image retrieval. The mean average precision (mAP) is used as the evaluation metric and the proposed method outperforms commonly-used methods. The baseline without feedback reached 16 % whereas the relevance feedback with 20 images reached up to 26.35 % with three steps and when using 100 images up to 34.87 % in four steps. Most improvements occur in the first two steps of relevance feedback and then results start to become relatively flat. This might also be due to only using positive feedback as negative feeback often also improves results after more steps. The effect of relevance feedback in automatically spelling corrected and translated queries is investigated as well. Results without mistakes were better than spell-corrected results but the spelling correction more than double results over non-corrected retrieval. Multimodal relevance feedback has shown to be able to help visual medical information retrieval. Next steps include integrating semantics into relevance feedback techniques to benefit from the structured knowledge of ontologies and experimenting on the fusion of text and visual information.
Dimitrios Markonis, Roger Schaer, Henning Müller
Inf. Retr. J.3
2016 How users search and what they search for in the medical domain - Understanding laypeople and experts through query logs
João R. M. Palotti, Allan Hanbury, Henning Müller, Charles E. Kahn Jr.
Inf. Retr. J.3
2016 Result diversification in social image retrieval: a benchmarking framework
Bogdan Ionescu, Adrian Popescu 0001, Anca-Livia Radu, Henning Müller
Multim. Tools Appl.4
2016 A 3-D Riesz-Covariance Texture Model for Prediction of Nodule Recurrence in Lung CT
abstract
This paper proposes a novel imaging biomarker of lung cancer relapse from 3-D texture analysis of CT images. Three-dimensional morphological nodular tissue properties are described in terms of 3-D Riesz-wavelets. The responses of the latter are aggregated within nodular regions by means of feature covariances, which leverage rich intra- and inter-variations of the feature space dimensions. When compared to the classical use of the average for feature aggregation, feature covariances preserve spatial co-variations between features. The obtained Riesz-covariance descriptors lie on a manifold governed by Riemannian geometry allowing geodesic measurements and differentiations. The latter property is incorporated both into a kernel for support vector machines (SVM) and a manifold-aware sparse regularized classifier. The effectiveness of the presented models is evaluated on a dataset of 110 patients with non-small cell lung carcinoma (NSCLC) and cancer recurrence information. Disease recurrence within a timeframe of 12 months could be predicted with an accuracy of 81.3-82.7%. The anatomical location of recurrence could be discriminated between local, regional and distant failure with an accuracy of 78.3-93.3%. The obtained results open novel research perspectives by revealing the importance of the nodular regions used to build the predictive models.
Pol Cirujeda, Yashin Dicente Cid, Henning Müller, Daniel L. Rubin, Todd A. Aguilera, Billy W. Loo, Maximilian Diehn, Xavier Binefa, Adrien Depeursinge
IEEE Trans. Medical Imaging3
2016 Cloud-Based Evaluation of Anatomical Structure Segmentation and Landmark Detection Algorithms: VISCERAL Anatomy Benchmarks
abstract
Variations in the shape and appearance of anatomical structures in medical images are often relevant radiological signs of disease. Automatic tools can help automate parts of this manual process. A cloud-based evaluation framework is presented in this paper including results of benchmarking current state-of-the-art medical imaging algorithms for anatomical structure segmentation and landmark detection: the VISCERAL Anatomy benchmarks. The algorithms are implemented in virtual machines in the cloud where participants can only access the training data and can be run privately by the benchmark administrators to objectively compare their performance in an unseen common test set. Overall, 120 computed tomography and magnetic resonance patient volumes were manually annotated to create a standard Gold Corpus containing a total of 1295 structures and 1760 landmarks. Ten participants contributed with automatic algorithms for the organ segmentation task, and three for the landmark localization task. Different algorithms obtained the best scores in the four available imaging modalities and for subsets of anatomical structures. The annotation framework, resulting data set, evaluation setup, results and performance analysis from the three VISCERAL Anatomy benchmarks are presented in this article. Both the VISCERAL data set and Silver Corpus generated with the fusion of the participant algorithms on a larger set of non-manually-annotated medical images are available to the research community.
Oscar Alfonso Jiménez del Toro, Henning Müller, Markus Krenn, Katharina Grünberg, Abdel Aziz Taha, Marianne Winterstein, Ivan Eggel, Antonio Foncubierta-Rodríguez, Orcun Goksel, András Jakab, Georgios Kontokotsios, Georg Langs, Bjoern Menze, Tomas Salas Fernandez, Roger Schaer, Anna Walleyo, Marc-André Weber, Yashin Dicente Cid, Tobias Gass, Mattias P. Heinrich, Fucang Jia, Fredrik Kahl, Razmig Kéchichian, Dominic Mai, Assaf B. Spanier, Graham Vincent, Chunliang Wang, Daniel Wyeth, Allan Hanbury
IEEE Trans. Medical Imaging2
2015 Workshop Multimodal Retrieval in the Medical Domain (MRMD) 2015
Henning Müller, Oscar Alfonso Jiménez del Toro, Allan Hanbury, Georg Langs, Antonio Foncubierta-Rodríguez
ECIR1
2015 Combining Unsupervised Feature Learning and Riesz Wavelets for Histopathology Image Representation: Application to Identifying Anaplastic Medulloblastoma
Juan Sebastian Otálora Montenegro, Angel Cruz-Roa, John Edison Arevalo Ovalle, Manfredo Atzori, Anant Madabhushi, Alexander R. Judkins, Fabio A. González 0001, Henning Müller, Adrien Depeursinge
MICCAI (1)8
2015 Div150Cred: A social image retrieval result diversification with user tagging credibility dataset
abstract
In this paper we introduce a new dataset and its evaluation tools, Div150Cred, that was designed to support shared evaluation of diversification techniques in different areas of social media photo retrieval and related areas. The dataset comes with associated relevance and diversity assessments performed by human annotators. The data consists of 300 landmark locations represented via 45,375 Flickr photos, 16M photo links for around 3,000 users, metadata, Wikipedia pages and content descriptors for text and visual modalities. To facilitate distribution, only Creative Commons content was included in the dataset. The proposed dataset was validated during the 2014 Retrieving Diverse Social Images Task at the MediaEval Benchmarking Initiative.
Bogdan Ionescu, Adrian Popescu 0001, Mihai Lupu, Alexandru-Lucian Gînsca, Bogdan Boteanu, Henning Müller
MMSys6
2015 Comparing image search behaviour in the ARRS GoldMiner search engine and a clinical PACS/RIS
Maria De-Arteaga, Ivan Eggel, Bao H. Do, Daniel L. Rubin, Charles E. Kahn Jr., Henning Müller
J. Biomed. Informatics6
2014 Khresmoi Professional: Multilingual, Multimodal Professional Medical Search
Liadh Kelly, Sebastian Dungs, Sascha Kriewel, Allan Hanbury, Lorraine Goeuriot, Gareth J. F. Jones, Georg Langs, Henning Müller
ECIR8
2014 Benchmarking result diversification in social image retrieval
abstract
This article addresses the issue of retrieval result diversification in the context of social image retrieval and discusses the results achieved during the MediaEval 2013 benchmarking. 38 runs and their results are described and analyzed in this text. A comparison of the use of expert vs. crowdsourcing annotations shows that crowdsourcing results are slightly different and have higher inter observer differences but results are comparable at lower cost. Multimodal approaches have best results in terms of cluster recall. Manual approaches can lead to high precision but often lower diversity. With this detailed results analysis we give future insights on this matter.
Bogdan Ionescu, Adrian Popescu 0001, Henning Müller, María Menéndez-Blanco, Anca-Livia Radu
ICIP3
2014 Gesture Interaction for Content-based Medical Image Retrieval
abstract
Large amounts of medical images are being produced to help physicians in diagnosis and treatment planning. These images are then archived in PACS (Picture Archival and Communication Systems) and usually they are only reused in the context of the same patient during further visits. Medical image retrieval systems allow medical professionals to search for images in institutional archives, the Internet or in the scientific literature. The goal of the search can be in diagnosis but often as well for teaching and research. A large body of research has investigated efficient and effective algorithms to retrieve a set of images to fulfil a specific information need. However, much less research has been done on studying simple and engaging interaction for users of medical image retrieval systems. In this paper we propose an intuitive and engaging web--based interface targeted to be used by a large range of users with gesture control. This interface allows users to retrieve medical images by accessing a system called Parallel Distributed Image Search Engine (ParaDISE), a text-- and content--based image retrieval system. Accepting search with keywords and example images, this interface uses simple gestures to get random example images and mark examples as positive and negative relevance feedback with results being updated after each interaction.
Antoine Widmer, Roger Schaer, Dimitrios Markonis, Henning Müller
ICMR4
2014 A Visual Information Retrieval System for Radiology Reports and the Medical Literature
Dimitrios Markonis, Rene Donner, Markus Holzer 0003, Thomas Schlegl, Sebastian Dungs, Sascha Kriewel, Georg Langs, Henning Müller
MMM (2)8
2014 Div400: a social image retrieval result diversification dataset
abstract
In this paper we propose a new dataset, Div400, that was designed to support shared evaluation in different areas of social media photo retrieval, e.g., machine analysis (re-ranking, machine learning), human-based computation (crowdsourcing) or hybrid approaches (relevance feedback, machine-crowd integration). Div400 comes with associated relevance and diversity assessments performed by human annotators. 396 landmark locations are represented via 43,418 Flickr photos and metadata, Wikipedia pages and content descriptors for text and visual modalities. To facilitate distribution, only Creative Commons content was included in the dataset. The proposed dataset was validated during the 2013 Retrieving Diverse Social Images Task at the MediaEval Benchmarking Initiative for Multimedia Evaluation.
Bogdan Ionescu, Anca-Livia Radu, María Menéndez-Blanco, Henning Müller, Adrian Popescu 0001, Babak Loni
MMSys4
2014 MedIR14: medical information retrieval workshop
abstract
Medical information is accessible from diverse sources including the general web, social media, journal articles, and hospital records; information searchers can be patients and their families, researchers, practitioners and clinicians. Challenges in medical information retrieval include: diversity of users and user knowledge and expertise; variations in the format, reliability, and quality of biomedical and medical information; the multi-modal nature of much of the data; and the need for accuracy and reliability of medical information. The aim of the workshop is to bring together researchers interested in medical information search with the goal of identifying specific challenges that need to be addressed to advance the state-of-the-art.
Lorraine Goeuriot, Gareth J. F. Jones, Liadh Kelly, Henning Müller, Justin Zobel
SIGIR4
2014 Three-dimensional solid texture analysis in biomedical imaging: Review and opportunities
Adrien Depeursinge, Antonio Foncubierta-Rodríguez, Dimitri Van De Ville, Henning Müller
Medical Image Anal.4
2014 Retrieval of high-dimensional visual data: current state, trends and challenges ahead
Antonio Foncubierta-Rodríguez, Henning Müller, Adrien Depeursinge
Multim. Tools Appl.2
2014 Rotation-Covariant Texture Learning Using Steerable Riesz Wavelets
abstract
We propose a texture learning approach that exploits local organizations of scales and directions. First, linear combinations of Riesz wavelets are learned using kernel support vector machines. The resulting texture signatures are modeling optimal class-wise discriminatory properties. The visualization of the obtained signatures allows verifying the visual relevance of the learned concepts. Second, the local orientations of the signatures are optimized to maximize their responses, which is carried out analytically and can still be expressed as a linear combination of the initial steerable Riesz templates. The global process is iteratively repeated to obtain final rotation-covariant texture signatures. Rapid convergence of class-wise signatures is observed, which demonstrates that the instances are projected into a feature space that leverages the local organizations of scales and directions. Experimental evaluation reveals average classification accuracies in the range of 97% to 98% for the Outex_TC_00010, the Outex_TC_00012, and the Contrib_TC_00000 suites for even orders of the Riesz transform, and suggests high robustness to changes in images orientation and illumination. The proposed framework requires no arbitrary choices of scales and directions and is expected to perform well in a large range of computer vision applications.
Adrien Depeursinge, Antonio Foncubierta-Rodríguez, Dimitri Van De Ville, Henning Müller
IEEE Trans. Image Process.4
2013 Epileptogenic Lesion Quantification in MRI Using Contralateral 3D Texture Comparisons
Oscar Alfonso Jiménez del Toro, Antonio Foncubierta-Rodríguez, María Isabel Vargas Gómez, Henning Müller, Adrien Depeursinge
MICCAI (2)4
2012 Multiscale Lung Texture Signature Learning Using the Riesz Transform
Adrien Depeursinge, Antonio Foncubierta-Rodríguez, Dimitri Van De Ville, Henning Müller
MICCAI (3)4
2012 Mobile Medical Visual Information Retrieval
abstract
In this paper, we propose mobile access to peer-reviewed medical information based on textual search and content-based visual image retrieval. Web-based interfaces designed for limited screen space were developed to query via web services a medical information retrieval engine optimizing the amount of data to be transferred in wireless form. Visual and textual retrieval engines with state-of-the-art performance were integrated. Results obtained show a good usability of the software. Future use in clinical environments has the potential of increasing quality of patient care through bedside access to the medical literature in context.
Adrien Depeursinge, Samuel Duc, Ivan Eggel, Henning Müller
IEEE Trans. Inf. Technol. Biomed.4
2012 Near-Affine-Invariant Texture Learning for Lung Tissue Analysis Using Isotropic Wavelet Frames
abstract
We propose near-affine-invariant texture descriptors derived from isotropic wavelet frames for the characterization of lung tissue patterns in high-resolution computed tomography (HRCT) imaging. Affine invariance is desirable to enable learning of nondeterministic textures without a priori localizations, orientations, or sizes. When combined with complementary gray-level histograms, the proposed method allows a global classification accuracy of 76.9% with balanced precision among five classes of lung tissue using a leave-one-patient-out cross validation, in accordance with clinical practice.
Adrien Depeursinge, Dimitri Van De Ville, Alexandra Platon, Antoine Geissbühler, Pierre-Alexandre Poletti, Henning Müller
IEEE Trans. Inf. Technol. Biomed.6
2011 Lung Texture Classification Using Locally-Oriented Riesz Components
Adrien Depeursinge, Antonio Foncubierta-Rodríguez, Dimitri Van De Ville, Henning Müller
MICCAI (3)4
2011 Special Section: Grid and Pervasive Computing 2009
Massimo Cafaro, Henning Müller, Nabil Abdennadher
Future Gener. Comput. Syst.2
2010 The ImageCLEF Medical Retrieval Task at ICPR 2010 - Information Fusion
abstract
An increasing number of clinicians, researchers, educators and patients routinely search for medical information on the Internet as well as in image archives. However, image retrieval is far less understood and developed than text-based search. The ImageCLEF medical image retrieval task is an international benchmark that enables researchers to assess and compare techniques for medical image retrieval using standard test collections. Although text retrieval is mature and well researched, it is limited by the quality and availability of the annotations associated with the images. Advances in computer vision have led to methods for using the image itself as search entity. However, the success of purely content-based techniques has been limited and these systems have not had much clinical success. On the other hand a combination of text- and content-based retrieval can achieve improved retrieval performance if combined effectively. Combining visual and textual runs is not trivial based on experience in ImageCLEF. The goal of the fusion challenge at ICPR is to encourage participants to combine visual and textual results to improve search performance. Participants were provided textual and visual runs, as well as the results of the manual judgments from ImageCLEFmed 2008 as training data. The goal was to combine textual and visual runs from 2009. In this paper, we present the results from this ICPR contest.
Henning Müller, Jayashree Kalpathy-Cramer
ICPR1
2010 Information Fusion for Combining Visual and Textual Image Retrieval
abstract
In this paper, classical approaches such as maximum combinations (combMAX), sum combinations (comb-SUM) and the product of the maximum and a non-zero number (combMNZ) were employed and the trade-off between two fusion effects (chorus and dark horse effects) was studied based on the sum of n maximums. Various normalization strategies were tried out. The fusion algorithms are evaluated using the best four visual and textual runs of the ImageCLEF medical image retrieval task 2008 and 2009. The results show that fused runs outperform the best original runs and multi-modality fusion statistically outperforms single modality fusion. The logarithmic rank penalization shows to be the most stable normalization. The dark horse effect is in competition with the chorus effect and each of them can produce best fusion performance depending on the nature of the input data.
Xin Zhou 0002, Adrien Depeursinge, Henning Müller
ICPR3
2010 Asymmetric-margin support vector machines for lung tissue classification
abstract
This paper concerns lung tissue classification using asymmetric-margin support vector machine (ASVM) to handle the imbalance of the positive and negative classes in a one-against-all multiclass classification problem. The hyperparameters of the algorithm are obtained using an optimization of the upper bound of the leave-one-out error of the ASVM. The ASVM is applied on the dataset with its original distribution and oversampled so that the ratio of the examples is equal to the prevalence of patients having the tissue in the database. The two versions of the ASVM models were compared with a model build with a conventional SVM. The ASVM improved the results obtained with a conventional SVM. The incorporation of prior knowledge concerning the prevalence of the patients improved the results obtained with ASVM.
Jimison Iavindrasana, Adrien Depeursinge, Gilles Cohen, Antoine Geissbühler, Henning Müller
IJCNN5
2010 Fusing visual and clinical information for lung tissue classification in high-resolution computed tomography
Adrien Depeursinge, Daniel Racoceanu, Jimison Iavindrasana, Gilles Cohen, Alexandra Platon, Pierre-Alexandre Poletti, Henning Müller
Artif. Intell. Medicine7
2010 Special issue on image and video retrieval evaluation
Allan Hanbury, Henning Müller, Paul D. Clough
Comput. Vis. Image Underst.2
2008 Lung Tissue Classification in HRCT Data Integrating the Clinical Context
abstract
In this paper, we investigate the influence of the clinical context of high–resolution computed tomography (HRCT) images of the chest on tissue classification. Evaluation of the classification performance is based on high–quality visual data extracted from clinical routine. The clinical attributes with highest information gain ratio show to be relevant and consistent for the classification of lung tissue patterns. A combination of visual and clinical attributes allowed a mean of 93% correct predictions of testing instances among the five classes of lung tissue with optimized support vector machines (SVM), which represents a significant benefit of 8% compared to a pure visually–based classification.
Adrien Depeursinge, Jimison Iavindrasana, Gilles Cohen, Alexandra Platon, Pierre-Alexandre Poletti, Henning Müller
CBMS6
2008 Using the Grid for Enhancing the Performance of a Medical Image Search Engine
abstract
In this paper we show how grid computing can be used to improve the operation of a medical image search system. The paper introduces the basic principles of a content-based image retrieval (CBIR) system and identifies the computationally challenging tasks in the system. For the computationally challenging tasks an efficient design is proposed that uses distributed grid computing to carry out the image processing in a distributed and efficient way. The algorithms of the search system are executed by using a real medical image collection as input and a grid computing infrastructure to provide the needed computing power. Finally, the results show how the image processing task that required tens of hours to complete can be processed by using only a fraction of the originally required computing time.
Mikko Juhani Pitkänen, Xin Zhou 0002, Antti Eero Johannes Hyvärinen, Henning Müller
CBMS4
2008 @neurIST - Towards a System Architecture for Advanced Disease Management through Integration of Heterogeneous Data, Computing, and Complex Processing Services
abstract
This paper presents the system architecture of the @neurIST project, which aims at supporting the research and treatment of cerebral aneurysms by bringing together heterogeneous data, computing and complex processing services. The architecture is generic enough to adapt it to the treatment of other diseases beyond cerebral aneurysms. The paper describes the generic requirements of the system and presents the architecture, applications and middleware technologies used to realise the system and highlights the innovations in @neurIST.
Hariharan Rajasekaran, Luigi Lo Iacono, Peer Hasselmeyer, Jochen Fingberg, Paul E. Summers, Siegfried Benkner, Gerhard Engelbrecht, Antonio Arbona, Alessandro Chiarini, Christoph M. Friedrich, Martin Hofmann-Apitius, Kai Kumpf, Bob Moore, Philippe Bijlenga, Jimison Iavindrasana, Henning Müller, Rod D. Hose, Robert Dunlop, Alejandro F. Frangi
CBMS16
2008 Automatic medical image annotation in ImageCLEF 2007: Overview, results, and discussion
Thomas Deselaers, Thomas M. Deserno, Henning Müller
Pattern Recognit. Lett.3
2008 Editorial to the Special Issue on Medical Image Annotation in ImageCLEF 2007
Thomas Deselaers, Henning Müller, Thomas M. Deserno
Pattern Recognit. Lett.2
2008 Hierarchical classification using a frequency-based weighting and simple visual features
Xin Zhou 0002, Adrien Depeursinge, Henning Müller
Pattern Recognit. Lett.3
2007 Medical Visual Information Retrieval: State of the Art and Challenges Ahead
abstract
Today's medical institutions produce enormous amounts of data on patients, including multimedia data, which is increasingly produced in digital form. These data in their clinical context contain much information and experience that is currently not being used up to its full potential. Through the digital form the data has become accessible for automatic analysis and treatment for a variety of applications. At the same time, the variety of images produced can be confusing even for trained specialists causing an information overload exists for many medical doctors. This suggests that content-based image retrieval can be a valuable tool for helping manage these data and access the right information at the right time. This article gives a short state of the art of content-based medical image retrieval followed by a description of the medGIFT project on image retrieval with its main components. Then, several challenges are used to illustrate areas where much more work is currently needed to advance biomedical image retrieval. This shows that we have now progresses beyond the phase, where medical doctors transfer a database to computer scientists to only evaluate their algorithms. We conclude that visual information retrieval can have a real impact in the medical field if the techniques can adapt to this rapidly changing field and get integrated into the workflow in radiology and other medical fields.
Henning Müller, Xin Zhou 0002, Adrien Depeursinge, Mikko Juhani Pitkänen, Jimison Iavindrasana, Antoine Geissbühler
ICME1
2007 The CLEF 2005 Automatic Medical Image Annotation Task
Thomas Deselaers, Henning Müller, Paul D. Clough, Hermann Ney, Thomas M. Deserno
Int. J. Comput. Vis.2
2006 Model Formulation: Advancing Biomedical Image Retrieval: Development and Analysis of a Test Collection
abstract
OBJECTIVE: Develop and analyze results from an image retrieval test collection. METHODS: After participating research groups obtained and assessed results from their systems in the image retrieval task of Cross-Language Evaluation Forum, we assessed the results for common themes and trends. In addition to overall performance, results were analyzed on the basis of topic categories (those most amenable to visual, textual, or mixed approaches) and run categories (those employing queries entered by automated or manual means as well as those using visual, textual, or mixed indexing and retrieval methods). We also assessed results on the different topics and compared the impact of duplicate relevance judgments. RESULTS: A total of 13 research groups participated. Analysis was limited to the best run submitted by each group in each run category. The best results were obtained by systems that combined visual and textual methods. There was substantial variation in performance across topics. Systems employing textual methods were more resilient to visually oriented topics than those using visual methods were to textually oriented topics. The primary performance measure of mean average precision (MAP) was not necessarily associated with other measures, including those possibly more pertinent to real users, such as precision at 10 or 30 images. CONCLUSIONS: We developed a test collection amenable to assessing visual and textual methods for image retrieval. Future work must focus on how varying topic and run types affect retrieval performance. Users' studies also are necessary to determine the best measures for evaluating the efficacy of image retrieval systems.
William R. Hersh, Henning Müller, Jeffery R. Jensen, Jianji Yang, Paul N. Gorman, Patrick Ruch
J. Am. Medical Informatics Assoc.2
2005 Evaluation axes for medical image retrieval systems: the imageCLEF experience
abstract
Content--based image retrieval in the medical domain is an extremely hot topic in medical imaging as it promises to help better managing the large amount of medical images being produced. Applications are mainly expected in the field of medical teaching files and for research projects, where performance issues and speed are less critical than in the field of diagnostic aid. Final goal with most impact will be the use as a diagnostic aid in a real--world clinical setting.Other applications of image retrieval and image classification can be the automatic annotation of images with basic concepts or the control of DICOM header information.ImageCLEF is part of the Cross Language Evaluation Forum (CLEF). Since 2004, a medical image retrieval task has been added. Goal is to create databases of a realistic and useful size and also query topics that are based on real--world needs in the medical domain but still correspond to the limited capabilities of purely visual retrieval at the moment. Goal is to direct the research onto real applications and towards real clinical problems to give researchers who are not directly linked to medical facilities a possibility to work on the interesting problem of medical image retrieval based on real data sets and problems. The missing link between computer science research departments and clinical routine is one of the biggest problems that becomes evident when reading much of the current literature on medical image retrieval. Most databases are extremely small, the treated problems often far from clinical reality, and there is no integration of the prototypes into a hospital infrastructure. Only few retrieval articles specifically mention problems related to the DICOM format (Digital Imaging and Communications in Medicine) and the sheer amount of data that needs to be treated in an image archive ( > 30.000 images per day in the Geneva radiology).This article develops the various axes that can be taken into account for medical image retrieval system evaluation. First, the axes are developed based on current challenges and experiences from ImageCLEF. Then, the resources developed for ImageCLEF are listed and finally, the application of the axes is explained to show the bases of the ImageCLEFmed evaluation campaign. This article will only concentrate on the medical retrieval tasks, the non-medical tasks will only shortly be mentioned.
Henning Müller, Paul D. Clough, William R. Hersh, Thomas Deselaers, Thomas M. Deserno, Antoine Geissbühler
ACM Multimedia1
2005 Evaluating user interactions with clinical information systems: A model based on human-computer interaction models
Christelle Despont-Gros, Henning Müller, Christian Lovis
J. Biomed. Informatics2
2004 Learning from User Behavior in Image Retrieval: Application of Market Basket Analysis
Henning Müller, Thierry Pun, David McG. Squire
Int. J. Comput. Vis.1
2003 A Framework for Benchmarking in CBIR
Henning Müller, Wolfgang Müller 0001, Stéphane Marchand-Maillet, Thierry Pun, David McG. Squire
Multim. Tools Appl.1
2001 Automated Benchmarking In Content-Based Image Retrieval
abstract
Benchmarking has always been a crucial problem in content-based image retrieval (CBIR). A key issue is the lack of a common access method to retrieval systems, such as SQL for relational databases. The Multimedia Retrieval Mark-up Language (MRML) solves this problem by standardizing access to CBIR systems (CBIRSs). Other difficult problems are also shortly addressed, such as obtaining relevance judgments and choosing a database for performance comparison. In this article we present a fully automated benchmark for CBIRSs based on MRML, which can be adapted to any image database and almost any kind of relevance judgment. The test evaluates theperformance of positive and negative relevance feedback, which can be generated automatically from the relevance judgments. To illustrate our purpose, a freely available, non-copyright image collection is used to evaluate our CBIRS, Viper. All scripts described here are also freely available for download.
Henning Müller, Wolfgang Müller 0001, David McG. Squire
ICME1
2001 Evaluating image browsers using structured annotation
abstract
Abstract In this article we address the problem of benchmarking image browsers. Image browsers are systems that help the user in finding an image from scratch, as opposed to query by example (QBE), where an example image is needed. The existence of different search paradigms for image browsers makes it difficult to compare image browsers. Currently, the only admissible way of evaluation is by conducting large‐scale user studies. This makes it difficult to use such an evaluation as a tool for improving browsing systems. As a solution, we propose an automatic image browser benchmark that uses structured text annotation of the image collection for the simulation of the user's needs. We apply such a benchmark on an example system.
Wolfgang Müller 0001, Stéphane Marchand-Maillet, Henning Müller, David McG. Squire, Thierry Pun
J. Assoc. Inf. Sci. Technol.3
2001 Performance evaluation in content-based image retrieval: overview and proposals
Henning Müller, Wolfgang Müller 0001, David McG. Squire, Stéphane Marchand-Maillet, Thierry Pun
Pattern Recognit. Lett.1
2000 Strategies for Positive and Negative Relevance Feedback in Image Retrieval
abstract
Relevance feedback has been shown to be a very effective tool for enhancing retrieval results in text retrieval. It has also been increasingly used in content-based image retrieval and very good results have been obtained. However, too much negative feedback may destroy a query as good features get negative weightings. This paper compares a variety of strategies for positive and negative feedback. The performance evaluation of feedback algorithms is a hard problem. To solve this, we obtain judgments from several users and employ an automated feedback scheme. We then evaluate different techniques using the same judgements. Using automated feedback, the ability of a system to adapt to the user's needs can be measured very effectively. Our study highlights the utility of negative feedback, especially over several feedback steps.
Henning Müller, Wolfgang Müller 0001, Stéphane Marchand-Maillet, Thierry Pun, David McG. Squire
ICPR1
2000 Content-based query of image databases: inspirations from text retrieval
David McG. Squire, Wolfgang Müller 0001, Henning Müller, Thierry Pun
Pattern Recognit. Lett.3
1998 A three-generation model for teleradiology
abstract
This paper proceeds from the definition of teleradiology. It identifies three different generations of teleradiology systems and includes those systems that are not regarded as teleradiology systems by the authors. A list of requirements pertinent to users of first-generation teleradiology systems is introduced. Most of the requirements have been realized in a new generation teleradiology system called CHILI.
Uwe Engelmann, Andre Schröter, Ulrike Baur, Oliver Werner, Markus Schwab, Henning Müller, Hans-Peter Meinzer
IEEE Trans. Inf. Technol. Biomed.6