Gait analysis is crucial for the diagnosis and monitoring of movement disorders like Parkinson's Disease. While computer vision models have shown potential for objectively evaluating parkinsonian gait, their effectiveness is limited by scarce clinical datasets and the challenge of collecting large and well-labelled data, impacting model accuracy and risk of bias. To address these gaps, we propose GAITGen, a novel framework that generates realistic gait sequences conditioned on specified pathology severity levels. GAITGen employs a Conditional Residual Vector Quantized Variational Autoencoder to learn disentangled representations of motion dynamics and pathology-specific factors, coupled with Mask and Residual Transformers for conditioned sequence generation. GAITGen generates realistic, diverse gait sequences across severity levels, enriching datasets and enabling large-scale model training in parkinsonian gait analysis. Experiments on our new PD-GaM (real) dataset demonstrate that GAITGen outperforms adapted state-of-the-art models in both reconstruction fidelity and generation quality, accurately capturing critical pathology-specific gait features. A clinical user study confirms the realism and clinical relevance of our generated sequences. Moreover, incorporating GAITGen-generated data into downstream tasks improves parkinsonian gait severity estimation, highlighting its potential for advancing clinical gait analysis.

Objective gait assessment in Parkinson’s Disease (PD) is limited by the absence of large, diverse, and clinically annotated motion datasets. We introduce Care-PD, the largest publicly available archive of 3D mesh gait data for PD, and the first multi-site collection spanning 9 cohorts from 8 clinical centers. All recordings (RGB video or motion capture) are converted into anonymized SMPL meshes via a harmonized preprocessing pipeline. Care-PD supports two key benchmarks: supervised clinical score prediction (estimating Unified Parkinson’s Disease Rating Scale, UPDRS, gait scores) and unsupervised motion pretext tasks (2D-to-3D keypoint lifting and full-body 3D reconstruction). Clinical prediction is evaluated under four generalization protocols: within-dataset, cross-dataset, leave-one-dataset-out, and multi-dataset in-domain adaptation.To assess clinical relevance, we compare state-of-the-art motion encoders with a traditional gait-feature baseline, finding that encoders consistently outperform handcrafted features. Pretraining on Care-PD reduces MPJPE (from 60.8mm to 7.5mm) and boosts PD severity macro-F1 by 17\%, underscoring the value of clinically curated, diverse training data. Care-PD and all benchmark code are released for non-commercial research (Code, Data).

Freezing of gait (FOG) is a common and severe symptom of Parkinson’s disease (PD). Due to the complex underlying pathophysiology, FOG is difficult to assess, hampering further insight into this phenomenon. Inertial measurement units (IMUs) may enable FOG assessment during everyday life, but lack of standardization, e.g., the number and position of the IMUs, complicates an objective comparison of automatic FOG assessment algorithms. We propose a multi-stage temporal dilated convolutional model to automatically assess FOG based on IMU data. We collected simultaneous optical motion capture (MoCap) and IMU data of ten people with PD and FOG. We devised a simulation pipeline, i.e., generating IMU data from MoCap data, to objectively compare our approach to two state-of-the-art FOG assessment models. The comparison was performed for five simulated IMU configurations, ranging from 1 to 7 IMUs. The results show that our approach outperforms the two state-of-the-art methods on most of the simulated IMU configurations. The complete lower-body IMU setup of 7 IMUs (pelvis and both sides of the talus, tibia, and femur) enables the best FOG detection performance. Lastly, we show that our model trained by incorporating simulated IMU data enabled significantly improved FOG detection performance than our model trained only with real IMU data. In doing so, we demonstrate that retrospective MoCap datasets can be re-used to train expressive IMU-based FOG assessment models, reducing the required amount of dedicated and labor-intensive IMU data collection experiments.

Human gait is an important indicator of health. Existing gait analysis systems are either expensive, intrusive, or require structured environments such as a clinic or a laboratory. In this research, a low-cost, non-obtrusive, dynamic gait monitoring platform is presented. By utilizing a mobile robot equipped with a Kinect sensor, comprehensive gait information can be extracted. The mobile platform tracks the skeletal joint movements while following the person. The acquired skeletal joint data is filtered to improve detection. Gait parameters such as step length, cadence and gait cycle time are extracted by processing the filtered data. The proposed approach was validated by using a VICON motion capture system. Results show that the proposed system is able to accurately detect gait parameters but requires a calibration procedure. Even though the camera is moving while tracking, the performance is on par with existing works. Step times can be detected with an average accuracy of around 10 milliseconds. Step length can be detected with an average accuracy of a few centimeters.