Overdraw is inevitable in large-scale scatterplots. Current scatterplot abstraction methods lose features in medium-to-low density regions. We propose a visual abstraction method designed to provide better feature preservation across arbitrary abstraction levels for large-scale scatterplots, particularly in medium-to-low density regions. The method consists of three closely interconnected steps: first, we partition the scatterplot into iso-density regions and equalize visual density; then, we allocate pixels for different classes within each region; finally, we reconstruct the data distribution based on pixels. User studies, quantitative and qualitative evaluations demonstrate that, compared to previous methods, our approach better preserves features and exhibits a special advantage when handling ultra-high dynamic range data distributions.

The overdraw problem of scatterplots seriously interferes with the visual tasks. Existing methods, such as data sampling, node dispersion, subspace mapping, and visual abstraction, cannot guarantee the correspondence and consistency between the data points that reflect the intrinsic original data distribution and the corresponding visual units that reveal the presented data distribution, thus failing to obtain an overlap-free scatterplot with unbiased and lossless data distribution. A dual space coupling model is proposed in this paper to represent the complex bilateral relationship between data space and visual space theoretically and analytically. Under the guidance of the model, an overlap-free scatterplot method is developed through integration of the following: a geometry-based data transformation algorithm, namely DistributionTranscriptor; an efficient spatial mutual exclusion guided view transformation algorithm, namely PolarPacking; an overlap-free oriented visual encoding configuration model and a radius adjustment tool, namelyfrdraw. Our method can ensure complete and accurate information transfer between the two spaces, maintaining consistency between the newly created scatterplot and the original data distribution on global and local features. Quantitative evaluation proves our remarkable progress on computational efficiency compared with the state-of-the-art methods. Three applications involving pattern enhancement, interaction improvement, and overdraw mitigation of trajectory visualization demonstrate the broad prospects of our method.

BACKGROUND: Bioinformatics has gained much attention as a fast growing interdisciplinary field. Several attempts have been conducted to explore the field of bioinformatics by bibliometric analysis, however, such works did not elucidate the role of visualization in analysis, nor focus on the relationship between sub-topics of bioinformatics. RESULTS: First, the hotspot of bioinformatics has moderately shifted from traditional molecular biology to omics research, and the computational method has also shifted from mathematical model to data mining and machine learning. Second, DNA-related topics are bridge topics in bioinformatics research. These topics gradually connect various sub-topics that are relatively independent at first. Third, only a small part of topics we have obtained involves a number of computational methods, and the other topics focus more on biological aspects. Fourth, the proportion of computing-related topics hit a trough in the 1980s. During this period, the use of traditional calculation methods such as mathematical model declined in a large proportion while the new calculation methods such as machine learning have not been applied in a large scale. This proportion began to increase gradually after the 1990s. Fifth, although the proportion of computing-related topics is only slightly higher than the original, the connection between other topics and computing-related topics has become closer, which means the support of computational methods is becoming increasingly important for the research of bioinformatics. CONCLUSIONS: The results of our analysis imply that research on bioinformatics is becoming more diversified and the ranking of computational methods in bioinformatics research is also gradually improving.

Zero-shot classification is a promising paradigm to solve an applicable problem when the training classes and test classes are disjoint. Achieving this usually needs experts to externalize their domain knowledge by manually specifying a class-attribute matrix to define which classes have which attributes. Designing a suitable class-attribute matrix is the key to the subsequent procedure, but this design process is tedious and trial-and-error with no guidance. This paper proposes a visual explainable active learning approach with its design and implementation called semantic navigator to solve the above problems. This approach promotes human-AI teaming with four actions (ask, explain, recommend, respond) in each interaction loop. The machine asks contrastive questions to guide humans in the thinking process of attributes. A novel visualization called semantic map explains the current status of the machine. Therefore analysts can better understand why the machine misclassifies objects. Moreover, the machine recommends the labels of classes for each attribute to ease the labeling burden. Finally, humans can steer the model by modifying the labels interactively, and the machine adjusts its recommendations. The visual explainable active learning approach improves humans' efficiency of building zero-shot classification models interactively, compared with the method without guidance. We justify our results with user studies using the standard benchmarks for zero-shot classification.

Revealing the evolution of science and the intersections among its sub-fields is extremely important to understand the characteristics of disciplines, discover new topics, and predict the future. The current work focuses on either building the skeleton of science, lacking interaction, detailed exploration and interpretation or on the lower topic level, missing high-level macro-perspective. To fill this gap, we design and implement Galaxy Evolution Explorer (Galex), a hierarchical visual analysis system, in combination with advanced text mining technologies, that could help analysts to comprehend the evolution and intersection of one discipline rapidly. We divide Galex into three progressively fine-grained levels: discipline, area, and institution levels. The combination of interactions enables analysts to explore an arbitrary piece of history and an arbitrary part of the knowledge space of one discipline. Using a flexible spotlight component, analysts could freely select and quickly understand an exploration region. A tree metaphor allows analysts to perceive the expansion, decline, and intersection of topics intuitively. A synchronous spotlight interaction aids in comparing research contents among institutions easily. Three cases demonstrate the effectiveness of our system.